Sumita D. Paul's research while affiliated with Massachusetts General Hospital and other places

... A larger multi-centre study, with stratified sampling may help to resolve some of these issues, and it is acknowledged that both geographical and individual consultant factors may confound treatment decisions. For instance there may be a proclivity to perform interventional cardiology in certain regions and/or that individual cardiologists may be referred particular patients, and have preferences for particular treatments [23]. More detailed analysis of such factors with a larger study sample may help to unravel how such factors confound treatment decision processes. ...

... Despite the higher procedural complications and 30-day readmission, the mean length of stay and hospital charges were less in women. Previous reports on sex difference in predictors of length of stay included diabetes, prior CABG or prior coronary angioplasty in men, and age alone in women [28]. Higher burden of comorbidities in men may have contributed to the increased length of stay. ...

... The main benefit of these systems is that they do not need extensive training or a computer to be calculated. There are many scoring systems in use today such as SAPS III [365], which predicts the mortality of ICU patients, QRISK2 [366] which is a prediction score for cardiovascular diseases, and Eagle score [367] which gives a probability for a patient dying during heart surgery. ...

... Perioperative MI is associated with high mortality ranging from 26-70% [1][2][3][4][5][6][7]. Therefore, it is imperative to identify patients who are at risk for untoward outcomes after surgery by using a systematic stepwise strategic preoperative evaluation such as that put forward in the guidelines of the ACC/AHA task force [8][9][10][11]. ...

... Tất cả bệnh nhân đều có bệnh lý kèm theo: tăng huyết áp (90%), đái tháo đường (56%) hoặc rối loạn chuyển hóa mỡ (30%),... Điều này làm tăng nguy cơ chu phẫu. Sự cố tim mạch có thể xảy ra 70-80% trong 4 năm sau phẫu thuật bắc cầu (7) . ...

... In cardiovascular disease, a validated difference exists in disease presentation, progress, and outcome between the sexes. [17][18][19] In the presence of carotid artery disease, women have less benefit from CEA compared with men. [1][2][3][4] The underlying pathophysiologic mechanisms that explain these sexspecific differences are poorly understood. ...

... Paul e cols. 17 também demonstraram que o tempo de aparecimento de 21 avaliaram, com a eletrocardiografia dinâmica, trinta pacientes com doença coronária estável e teste ergométrico positivo, também encontrando FC menor no aparecimento da isquemia na eletrocardiografia (98,0±20,5 versus 124,0±17,0 bpm). Embora haja a influência dos fatores determinantes do consumo de oxigênio na gênese dos episódios isquêmicos às atividades habituais, como se depreende do que ocorre durante o teste de esforço, também a sua variação, e não apenas seu valor absoluto, pode determinar isquemia, como se observa na eletrocardiografia de 24 horas. ...

... 6,7 The elderly are a vulnerable group due to the physiological characteristics of aging, their lifestyles and socioeconomic conditions, and their comorbidities. 8,9 Advanced age is considered to be a risk factor for cardiovascular death, which increases with age, making ACS one of the main causes of death in the elderly. 10,11 Treatment in this population has been a matter of debate, since most studies and clinical trials exclude people over the age of 80. 12 This occurs with myocardial revascularization, an option which is generally unavailable for the most elderly, due solely to their age. ...

... Selected 30 male and female individuals' samples (14 critical CAD patients and 16 non-CAD controls) were included in the study. Critical CAD has been defined as ≥ 70% stenosis in ≥ 1 coronary artery while non-CAD is defined as ≤ 20% stenosis in coronary arteries [13]. Following angiography, the Gensini and SYNTAX scores (version 2.28, www. ...

... Our study was comparable to the Italian study in observing a higher prevalence of adverse risk factors among syncope patients hospitalized compared with among patients discharged but further extends this finding specifically to patient's sex. Although, our cohort consisted of patients with a primary discharge diagnosis of syncope, prior studies have found older age and cardiac comorbidities are related to cardiac causes of syncope that are more frequently observed among men whereas noncardiac causes of syncope are often found in women (34)(35)(36). Men have been found to have worse cardiac event-free survival (33) than women who are hospitalized, and male sex has been identified as an independent predictor of inhospital or short-term all-cause mortality among hospitalized cohorts (13,27,37,38). After adjusting for confounders, we also found male sex, compared with female sex, is associated with a 1. patients. ...