Süliová J’s research while affiliated with University of Veterinary Medicine in Košice and other places

... No case of post-vaccination rabies was detected using monoclonal antibodies (Durove et al., 1996;Ondrejka et al., 1997). In the following years, vaccination was only performed in 19 districts over an area of 14 517 square kilometres in 1997. ...

Reference:

A review of rabies elimination in Europe

... – Serological examination – the rabies antibodies titres in mice sera were detected by ELISA method using the ELISA kit developed in our laboratory (Bení{ek et al., 1989; Süliová et al., 1994). Statistical evaluation of results of rabies antibody titres was carried out by Student t-test. ...

Reference:

Injectious rabies vaccines effectiveness evaluation: Alternatives

... No case of post-vaccination rabies was detected using monoclonal antibodies (Durove et al., 1996;Ondrejka et al., 1997). In the following years, vaccination was only performed in 19 districts over an area of 14 517 square kilometres in 1997. ...

Reference:

A review of rabies elimination in Europe

... Rabies virus (RABV) is a negative sense single-stranded RNA virus with a typical bullet shape belonging to the genus Lyssavirus. RABV causes encephalitis in humans with a fatality rate of nearly 100% [1,2]. Dog bites from rabid animals are the most common cause of infection in humans. ...

Reference:

IMT504: A New and Potent Adjuvant for Rabies Vaccines Permitting Significant Dose Sparing

... Group III cattle vaccinated intradermally had reached the antibody titre of >2.5 IU/ml on 28 th day post vaccination as that of Group II cattle vaccinated intramuscularly but the immune response in Group I (sc) cattle was lower than other two groups. This  nding is in accordance with Madar et al. (1998) who found the immune response of intradermal vaccination was as effective as standard intramuscular vaccination. ...

Reference:

Vaccination studies against rabies in farm and pet animals using different immunization routes

... An adjuvant of the oil-in-water type (O/W) (Süliova et al., 1999), based on fully metabolisable (Bomford, 1981) isopropyl palmitate (IPP) – isopropylester of palmitic acid was developed in our laboratory. This adjuvant has excellent properties (Bení{ek et al., 1999); however, its disadvantage is that it can be used only for resuscitation of lyophilised vaccines and not for potentiation of liquid inactivated vaccines. The only permitted adjuvant except aluminium compounds in human medicine is the MF59 formulation, an adjuvant of O/W type based on squalene as lipid component and detergents Tween 80 and Span 85. ...

Reference:

A new rabies vaccine with an experimental adjuvant for domestic animals

... The development of new vaccine adjuvants (combined adjuvants) has been hampered by their unacceptable reactogenicity [6]. We prepared in our laboratory an emulsion of oil-in-water type based on esters of fatty acids, namely izopropylester of palmitic acid with the use of block co-polymer Poloxamer 105 (pluronic polyol) as an emulsifier with marked adjuvant activity [7,8]. Pluronic polyols are a family of non-ionic surfactants currently used as drug carriers for antibiotic , anti-inflammatory and anti-neoplastic agents [9]. ...

Reference:

Experimental squalene adjuvant: II. Harmlessness and local reactogenity

... To overcome this issue, selection of a powerful adjuvant has become of prime importance [7]. Aluminum hydroxide gel, the most common adjuvant, has been principally employed [8,9]. Recently, various adjuvants for use in animal vaccines have been developed to promote the maturation of bone marrow-derived dendritic cells, thus inducing strong immune responses [10]. ...

Reference:

Immunogenicity of an inactivated rabies vaccine for animals derived from the recombinant ERAGS strain