Sudhaa Sharma's research while affiliated with Department of Education,Government of Jammu and Kashmir and other places
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Publications (39)
Preliminary data depicts a much greater prevalence and high case-fatality rate in advanced age males as compared to age-matched women with severe acute respiratory syndrome-coronavirus-2 infections with high morbidity, mortality, high referral, and admission to intensive care unit with severe sequelae. However, the literature search revealed both f...
Women are likely to suffer from sleep disorders more in comparison to men during menopause and with advancing age. The incidence of sleep disorders ranges from 16% to 47% at peri-menopause and 35%–60% at postmenopause. Insomnia with or without associated anxiety or low lying depression and Mood disorder is most common associated manifestations. Sle...
Aims and objectives:
The aim of this study is to compare the effect of clonazepam and nortryptiline on menopausal symptoms in above 40 years women.
Materials and methods:
A prospective, randomized, open-label comparative study was conducted in a tertiary care teaching hospital for 1 year. Patients were randomized into two groups. Both the groups...
Aims and objectives:
The aim of this study is to compare the effect of clonazepam and nortriptyline on rate, frequency, and severity of restless leg syndrome (RLS) in above 40 years women suffering from RLS.
Materials and methods:
A prospective, randomized, open-label comparative study was conducted at a tertiary care teaching hospital for 1 yea...
Introduction
Restless legs syndrome (RLS) is a neurological disorder characterized by an urge to move the legs usually accompanied by unpleasant leg sensations. RLS also impacts health related quality of life (QOL) in patients suffering from it. Further, it affects women more than men. Although a voluminous literature of studies is available evalua...
Introduction: Oral antihyperglycaemic prescription trends keep
on changing and thus the drug prescription trend study may prove
to be powerful exploratory tool for health care providers.
Aim: To investigate trends in prescriptions of oral
antihyperglycaemic drugs (OHDs) among postmenopausal women
suffering from T2DM in India and evaluate the ration...
Zidovudine is an important component of first-line antiretroviral treatment regimens used to manage HIV and tuberculosis (TB) co-infection. Nail pigmentation is documented both in adult as well as pediatric HIV patients, but to the best of our knowledge, it has not been reported in 45-year-old women of HIV/TB co-infection. Such an adverse drugs rea...
Bisphosphonates (BP) are the mainstay of treatment for osteoporosis. Subtrochanteric or diaphyseal fractures have been reported with long term use of BP, which raised world-wide debate on two aspects, i.e., for how long the BP is to be given and potential advantages/role of BP drug holidays. BP accumulates in bone with some persistent protective ef...
Aim and Objective:
To evaluate prevalence of Vitamin D deficiency and establish any correlation between diabetes and vitamin D deficiency among postmenopausal women.
Materials and Methods:
The 25-hydroxy vitamin D [25 (OH) D] concentrations were measured by competitive in-vitro quantitative immunoassay. The subjects were classified as vitamin D-de...
Aim of Study:
The aim of this study is to evaluate antihypertensive drug prescription patterns, rationality and adherence to Joint National Committee (JNC-7) hypertension (HT) treatment recommendations among Indian postmenopausal women (PMW).
Materials and Methods:
An observational and cross-sectional prospective prescription audit study was carri...
![Table 2 ].](publication/261140208/figure/tbl1/AS:601616122130435@1520447869053/93-46_Q320.jpg)
The aim of the following study is to evaluate the effect of life-style modification on postmenopausal (PM) overweight and obese Indian women in a randomized controlled 24 week study.
Two groups were formed Group I (n = 30) was designated as intervention (dietary and exercise group) and Group II (n = 24) served as control. Comparison of weight, wais...
The aim of the following study is to evaluate adherence and compliance of postmenopausal osteoporotic patients for different regimens of bisphosphonates (BP).
A prospective observational randomized comparative 1 year study was undertaken to evaluate the adherence/compliance rates of most commonly prescribed daily alendronate (ALN), weekly risedrona...
Osteoporosis and obesity are worldwide health problems. Interestingly, both are associated with significant morbidity and mortality. Both the diseases have common linkage as bone marrow mesenchymal stromal cells are the common precursors for both osteoblasts and adipocytes. Aging may shift composition of bone marrow by increasing adipocytes, osteoc...
Fondaparinux sodium is a synthetic, sulfated pentasaccharide, selective factor Xa inhibitor, a safe and effective antithrombotic agent indicated for preventing thrombus formation in patients with acute coronary syndromes, including those with ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), or unstable angina. Major bleeding...
The present observational, cross-sectional prospective study was conducted during the period of 1 year in one of the rural health centers to study prevalence of conventional cardiovascular disease risk factors (CVRFs) in postmenopausal women.
Five hundred consecutive postmenopausal women were screened for detailed information regarding common menop...
The review summarizes recent findings with respect to pathophysiological role of calcitonin gene-related peptide (CGRP), in postmenopausal symptoms and diseases, which has opened horizons in understanding pathophysiology of menopause in a better way. Current evidences strongly propose a need to develop CGRP receptor antagonists, which may prove ben...
Current H1N1 virus has been found to contain a unique combination of genes from pig, bird and human flu viruses. This peculiar recombinant influenza virus is entirely new and has not been seen before (1). This creates an almost universal vulnerability to infection in nearly all people. Therefore, the emergence of H1N1 infection among humans present...
JK Science celebrates successful decade of publishing unbiased and quality research. It is a multi-disciplinary,peer reviewed, open access medical journal being published quarterly from Jammu, J&K India.
The present observational, cross sectional study was carried out in urban women (n=117) from Jammu withnatural menopause to evaluate menopausal symptoms in women above the age of 40 belonging to the middlesocioeconomic strata from Jammu (extreme northern India) as well as to evaluate the correlation of age onthese symptoms by interviewing regarding...
Pregnancy in most cases, is associated with remission of rheumatoid arthritis (RA), but a quarter of patients continue to have active disease or even worsening of the disease and most patients who improve, relapse in the postpartum period. The pathophysiology of this improvement in disease activity during pregnancy remains unknown, but hormonal, ce...
Pregnancy in most cases, is associated with remission of rheumatoid arthritis (RA), but a quarter of patients continue to have active disease or even worsening of the disease and most patients who improve, relapse in the postpartum period. The pathophysiology of this improvement in disease activity during pregnancy remains unknown, but hormonal, ce...
Unethical Publication Practice is a global problem.
Journals at large are facing a huge problem of unethical
practices in the publication. JK Science strongly
discourages such practices and aims to bring this serious
issue in notice.
Osteoporosis is a major public health problem, associated with substantial morbidity and socio-economic burden. An early detection can help in reducing the fracture rates and overall socio-economic burden in such patients.
The present study was carried out to screen the bone status (osteopenia and osteoporosis) above the age of 25 years in urban wo...
BACKGROUND: Osteoporosis is a major public health problem, associated with substantial morbidity and socioeconomic burden. An early detection can help in reducing the fracture rates and overall socioeconomic burden in such patients. AIM: The present study was carried out to screen the bone status (osteopenia and osteoporosis) above the age of 25 ye...
Citations
... Instead, we added clonazepam before taking olanzapine as it was a safe drug for these patients and effective in treating RLS. 3,16 ...
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... There are no randomized placebo-controlled clinical trials that assess the effectiveness of benzodiazepines for RLS/WED [100]. One randomized open-label trial showed that clonazepam, compared with nortriptyline, improved quality of life from RLS/WED in middle-aged women [101]. There are additional risks of dependence and tolerance, sedation, drowsiness, and falling. ...
... Zidovudine is one of the first-line antiretroviral therapy (ART) regimen drug used to treat human immunodeficiency virus (HIV) infected patients [1][2][3]. Nail pigmentation associated with zidovudine therapy is seen in adults and children's, mainly dark-skinned patients [4]. This grayish blue discoloration of the nails seems to be reversible and comparatively dose-dependent [5][6][7]. ...
... However, the findings of the current study is in consonance with the conclusion of other studies that showed that metformin is the most prescribed drug for both genders in monotherapy and fixed-dose combination therapy, with a higher percentage for females than males (Arnetz, Ekberg, Alvarsson, 2014). Moreover, it was observed that the pattern of antidiabetic prescription for female patients in this study matched the results of another study conducted in Indian where the pattern was in the order of biguanides followed by sulfonylureas (Sharma, Tandon, Roshi Mahajan, 2016). ...
Reference: download (1)
... The concept of a "drug holiday" has been proposed to potentially reduce the incidence of the rare adverse events associated with long-term anti-resorptive therapy [99]. However, the recommendation for drug holidays is still a matter of debate [100], especially since there is a dearth of data from India. However, the Endocrine Society guidelines 2020 do recommend a drug holiday in selected groups of patients [59]. ...
... The Prevalance of vitamin D deficiency collected from previous epideomological studes. [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] Diagnostic cut-offs of levels of serum Vitamin D status mentioned in table 1. ...
... [2] Epidemiological studies demonstrate that prevalence of hypertension is increasing rapidly among urban and rural populations in India. [3][4][5][6] Selection of an evidence-based therapy with safety and low cost has important economic implications. Clinical pharmacists can play a role in pharmaceutical cost management by providing an outlook to the physicians for prescribing cost-effective choices of drugs when it is clinically appropriate. ...
... In a study assessing treatment algorithms in patients with osteoporosis in India, most clinicians preferred bisphosphonates as the first line of therapy [84]. However, in another study that aimed explicitly to evaluate the treatment adherence and compliance of postmenopausal osteoporotic women for different regimens of bisphosphonates in Indian postmenopausal women, the authors found that an adherence rate of 56% was found with the monthly regimens, 36% for weekly regimens, and 32% for daily regimens [85]. Herein lies the paramount importance of continuous monitoring and vigilant follow-up. ...
... On the other hand, these interventions were not based on self-management and CBT and did not specify the extent of the effect of the interventions in the analysis of their data to allow an accurate comparison. This study was also consistent with the research by Tandon et al. [33] and Moradi et al. [34] but was not consistent with the Sekendiza et al. study [35]. The passive educational method was used in these studies, such as lecturing or using booklets and pamphlets or only in a specific dimension of lifestyle, such as physical activity was considered. ...
... This is an indication that obesity is protective against the disease, even though previous studies have suggested otherwise. 31 Previous data have shown that osteoporosis and obesity are related based on how obesity is defined (ie, based on body mass index or body weight, which makes it protective, or according to the percentage of body fat, which makes it a risk factor). 32 It should be noted that we used BMI to define obesity following the Health Promotion Administration guidelines. ...
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