Stephen Spreiter’s research while affiliated with Stanford University and other places

We reevaluated six patients in whom the diagnosis of orthostatic proteinuria was made by Thomas Addis 42 to 50 years ago. Three had died of nonrenal causes (pulmonary carcinoma, myocardial infarction, and trauma) 42, 45, and 50 years after diagnosis; no renal disease was ever detected in any of these three. The other three are alive 42 to 45 years later, without proteinuria and with apparently normal renal function, although one initially had an extremely severe disease process with decreased renal function. Three of the five men had transitory urinary-tract infections within the past decade. Thus, one can expect long-term survival of patients with postural proteinuria.