Sridevi Hanaganahalli Basavaiah's research while affiliated with Manipal Academy of Higher Education and other places

... Over the next years, CPD were made available in more analyzer brands [8][9][10] and the number of disease states where neutrophil CPD are considered useful nowadays includes neonatal and adult sepsis [8,[11][12][13], postoperative infection [14], tuberculosis [15], myelodysplastic syndrome [16,17], acute and chronic leukemia [18][19][20] and transplant engraftment [21,22]. Lymphocyte CPD can provide additional information in viral infection [23], lymphocytosis [24][25][26] and tropical infections like dengue [27,28]. The significance of monocyte CPD was boosted by the Covid-19 pandemic, as monocyte volume distribution width (MDW) was found to have prognostic value ...

... Also, mathematical models to assess the effects of mosquito resistance to insecticides have been proposed and analyzed (Barbosa and Hastings, 2012;Birget and Koella, 2015; Barbosa et al., 2018;Mohammed-Awel et al., 2018Ngonghala et al., 2020). Although there is overwhelming evidence of asymptomatic malaria transmission (i.e., transmission of the malaria disease by humans with malaria parasite burden, but who do not exhibit clinical symptoms of malaria) in different parts of the world (Bousema et al., 2004;Eke et al., 2006;Lindblade et al., 2013;Lopez-Perez et al., 2015;Sáenz et al., 2017;Tiono et al., 2014;Jiram et al., 2019;Chaumeau et al., 2019;Ramaswamy et al., 2020;Sumner et al., 2021), only few mathematical models have attempted to quantify the impact of asymptomatic infection on malaria spread and persistence through a separate asymptomatic human carrier class (e.g., Filipe et al. (2007) and Aguilar and Gutierrez (2020)). The existence of asymptomatic infectious humans complicates disease control efforts. ...

... While distinguishing between T-lymphoblastic leukemia (T-ALL) and mature T-cell neoplasms is usually very straightforward with the presence of immature markers such as CD1a, CD34, and TdT in the former, there have been unusual cases of T-prolymphocytic leukemia, T-PLL seen with lack of surface CD3 and CD45 that can make the diagnosis more difficult (26,27). Similarly, there have been reports of mature T-cell neoplasms aberrantly expressing immature markers, such as CD1a (28,29). ...

... 21,30 Studies have suggested that the persistence of paraprotein after treatment may be indicative of progression to MM and it is the only independent adverse prognostic factor for myeloma free survival. 31,32 Histopathologically, it is necessary to differentiate SPB from plasmablastic lymphoma (PBL), reactive inflammatory lesions (plasma cell gingivitis), non-Hodgkin's lymphoma and melanoma which presents a diagnostic challenge to clinicians. 1,8 Features such as neoplastic cells exhibiting abundant cytoplasm, vesicular chromatin and central nuclei with prominent nucleoli are commonly observed in PBL. ...

... The literature is also unclear as to the optimal treatment regimens for the combined presentation of CD5+ DLBCL with leukemic transformation. An increasing number of case reports separately detail both DLBCL with leukemic transformation [7][8][9][10][11] and CD5 positivity [4,12], but mentions of dual presentation have been limited, as have case series and larger studies [5][6]. The authors of these reports, where treatment is discussed, ultimately favor an anthracycline-based treatment regimen, often paired with rituximab, though R-hyper-CVAD with alternating IT MTX/cytarabine [13] has also been reported. ...

... Another Indian study similarly reported a megaloblastic blood picture in malaria cases. 16 We did not find any pigment. ...

... First of all, there are difficulties in pathologic interpretation on biopsy samples, particularly in the distinctions between benign papillomas, papilloma with ADH/DCIS and papillary carcinomas. These problems mainly arise in overlapping morphological features and, sometimes, immunohistochemistry staining could be not helpful [34]. Second, there may be a risk of underestimation of malignancy or atypia due to sampling error. ...