Sourav Banerjee’s scientific contributions

There are many small or undeveloped countries whose economy depends on agricultural production. A healthy agriculture production depends on various factors like soil quality, water, fertilizer, skilled labor, and many more. Fertilizer is the most crucial things that influence agricultural production. A fertilizer is a kind of chemical or natural substance that is helpful in crop production. However, to achieve quick agricultural yields we usually used chemical fertilizer which is very responsive to biofertilizer but the chemical fertilizer is not as eco-friendly as biofertilizer. Biofertilizer are natural fertilizes which are living microbial inoculants of bacteria, algae, fungi alone or in combination and they augment the availability of nutrients to the plants. Mycorrhizal fungi preferentially withdraw minerals from organic matter for the plant whereas cyanobacteria are characterized by the property of nitrogen fixation. The role of biofertilizer in agriculture assumes special significance, particularly in the present context of increased cost of chemical fertilizer and their hazardous effects on soil health. Agricultural fertilizers are essential for proper crop growth and yield. Chemical fertilizers have recently been used by farmers to increase yield and speed up the process. Natural biofertilizer, on the other hand, not only have a higher yield but are also safe for humans. The benefits of biofertilizer include low cost, enhanced nutrient availability, improved soil fertility, protect plants from soil-borne pathogens, sustainable agricultural production, enhanced biotic and abiotic stress tolerance, promote phytohormone production, improve soil health, causing less environmental pollution, and its continued use improves the fertility of soil considerably.

A gynecological malignancy with a high mortality rate and a variety of forms, ovarian cancer is challenging to identify early and prevent. Numerous studies have examined the expression profile of microRNAs (miRNAs) in tissue and serum samples of patients to discover pertinent biomarkers for ovarian cancer. Functional tests also demonstrated that a number of miRNAs had oncogenic or suppressive effects. Despite the invention of various biological markers, mostly mRNA and protein, ovarian cancer mortality remains a problem due to late detection, which is related to low specificities and sensitivities. Recent advancements in expression biology have turned towards this compulsive direction for cancer diagnosis and prognosis; focusing on identification and development of specific and sensitive biomarkers, such as microRNAs (miRNAs). A number of miRNAs, including miR-23b, miR- 146b, miR-200-a/b/c, miR-630, miR-31 influence the epithelial-mesenchymal transition pathway, modulating ovarian cancer cell invasiveness. MiRNAs have such a broad range of functions in ovarian cancer that they have been recommended as potential treatment strategies in the future. In this review, we discuss the role of various micro RNAs and the genes they target in the pathogenesis of ovarian cancer, as well as the potential applications of these molecules as biomarkers.