Somya Ranjan Panda’s research while affiliated with GIET University and other places

Drug-resistant infection is becoming more common, which makes it essential to use modern analytical techniques to find and isolate novel bioactive chemicals from medicinal plants. Throughout ancient times, people utilised plants to preserve and enhance food, heal illnesses, provide medical treatment, and avert epidemics. Plant extracts can attach the protein domain and alter their interaction with other proteins or domain, thus influencing their biological activity. It allows the herbs to demonstrate their efficacy as host-related cellular immunological responses. Due to the enormous diversity of secondary metabolites found in medicinal plant extracts, this extract may offer an alternative supply of agents that modulate resistance. Recent research has scientifically confirmed the antimicrobial properties of several plants, which were not emphasized earlier. This review focuses on the potential chemical properties of plant-derived compounds and their mechanism of antimicrobial action. The emphasis is on the present difficulties and the outlook for medicinal plants’ antimicrobial properties in future. The present review explores potential role and applications of several plant-derived products in treating antimicrobial disease for defended human health and animals. It intensifies the desirable application of conventional plant products of phytocompound.

Tuberculosis (TB), caused by the bacterial organism Mycobacterium tuberculosis, has remained a persistent global health challenge, profoundly impacted millions of lives and posed a significant threat to public health worldwide. Despite notable strides in medical research, TB continues to be a formidable issue, particularly in underdeveloped nations. The existing arsenal of tuberculosis treatment options is notably limited, and the emergence of multi- and extensively drug-resistant TB strains further complicates the situation. The escalating costs of new pharmaceuticals and the adverse effects associated with current prescription treatments have prompted a compelling need to explore alternative approaches. In response, attention has increasingly turned towards investigating natural substances as supplementary treatment options. Derived from diverse biological sources, these natural products, including plant extracts, microbial metabolites, and compounds from marine origins, are gaining popularity as potential complements or substitutes for established anti-mycobacterial interventions. This exploration represents a promising avenue for addressing the complexities of TB treatment while considering cost-effectiveness and mitigating adverse drug reactions.