Siyang Wang's scientific contributions

Publications (5)

Article
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Background: Since postoperative pulmonary complications are one of the main causes of morbidity and mortality in patients undergoing lung resection surgery, we performed a meta-analysis to compare the incidence of postoperative pulmonary complications and hospital death, and the length of hospital stay in patients who received nonintubated or intu...
Article
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Background Acute renal injury (AKI) is a common renal complication after cardiac surgery. The aim of this study was to determine the effect of perioperative statin therapy (PST) on postoperative renal outcome in patients undergoing cardiac procedures. Methods We searched for the reports that evaluating the effect of PST on renal outcomes after car...
Article
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Remote ischemic preconditioning (RIPC) may attenuate acute kidney injury (AKI). However, results of studies evaluating the effect of RIPC on AKI after cardiac surgery have been controversial and contradictory. The aim of this meta-analysis is to examine the association between RIPC and AKI after on-pump cardiac surgery. The authors searched relevan...
Article
Full-text available
Objective To determine whether patients with severe sepsis or septic shock could benefit from a strict and early goal-directed therapy (EGDT) protocol recommended by Surviving Sepsis Campaign (SSC) Guidelines. Methods MEDLINE/PubMed, EMBASE/OVID and Cochrane Central Register of Controlled Trials (CENTRAL) were searched between March 1983 and March...

Citations

... Surgical factors that may necessitate conversion to GETA include poor maneuverability of instruments due to excessive respiratory movement of the lung and mediastinum, patient movement, pleural adhesions preventing lung collapse, and bleeding. Anesthesia-related factors that require conversion to GETA include intractable hypoxia, hypercarbia, and hemodynamic instability [43]. This is why the anesthesia team has to be vigilant in monitoring these patients. ...
... and other meta-analyses, with 1 suggesting that although the class, on the whole, may not provide benefit, rosuvastatin may increase risk. 77 80,81 A large, retrospective, observational study provided further contention with preoperative use associated with a lower incidence of all-stage CSA-AKI compared with control (31% v 36%, p < 0.001). 82 Currently, there is no renal indication for use, but continuation until surgery is appropriate and further evidence is required. ...
... but no impact on RRT requirement. 201 However, a similar-sized meta-analysis (21 trials, n = 5,262) found no reduced CSA-AKI incidence (a co-primary outcome), and a Cochrane Database Systematic Review (primary outcome, 28 studies, n = 6,851) found similar, reporting a minimal impact for one AKI criteria alone (Acute Kidney Injury Network: risk ratio 0.76 [0.57-1.0]). 202,203 In contrast, another RCT (the RenalRIPC study) reported reductions in CSA-AKI and major adverse kidney events with RIPC compared with a sham intervention (AKI: 38% v 53%, p = 0.02; major adverse kidney events: 14% v 25%, p = 0.03). ...
... Hence, a crystalloid bolus of 40% of the circulating blood volume (or 66% of the circulating plasma volume) within 1 hour of presentation to the ED should be reconsidered. [6][7][8] Deeper understanding of the underlying complex pathology (like primary and secondary organ dysfunction, the often-impaired cardiac function and the pronounced venous vasoplegia) has raised concerns about the validity of evidence base of the mandatory 30 mL/kg crystalloid resuscitation. [9][10][11][12][13] To the best of our knowledge, no systematic review has been published in either emergency or prehospital settings investigating the optimal rate/ volume of fluid resuscitation for adult patients screened positive for sepsis. ...