Sidharth Mohanty’s research while affiliated with Apollo Hospitals and other places

Recurrent respiratory papillomatosis (RRP) is a benign lesion seen in the respiratory airway caused by human papillomatosis virus (HPV).RRP can affects children to young adults. Most of the childhood RRP occur at birth which contaminated from birth canals of the mother. In adult ages, the infections transmitted via sexual route. The lesions are often seen as exophytic nodules, mostly in the larynx and occasionally at the nasopharynx, tracheobronchial trees and lung parenchyma. This disease is often unpredictable and varies from spontaneous remission to aggressive persistent or recurrence in nature.RRP has chance for malignant transformation to squamous cell carcinoma although it is a rare happening. The diagnosis is confirmed by histopathological study. Presently there is no definite treatment for RRP available. Surgery is the treatment of choice along with several adjuvant therapies available. The aim of this review article is to describe the detail etiology, epidemiology, clinical presentations, investigations and treatment of RRP.

Superior semicircular canal dehiscence syndrome (SSCDS) is a rare and recently described inner ear lesion presenting with disequilibrium and associated with dehiscence of the bony covering of SSC. SSCDS patients may present with a variety of vestibular or auditory symptoms or both. Patients present with vertigo induced by sound or pressure. The diagnosis of SSCDS depends on the demonstration of a defect in the bony wall of the roof of the SSC. A high-resolution computed tomography is helpful for diagnosis. It is usually treated by plugging of dehiscence. The aim of this review article is to discuss the etiopathology, clinical presentation, investigations, and recent treatment of SSCDS.

Objective: This double-blind randomized trial was conducted to compare the efficacy of selective nerve blocks over intravenous use of morphine during mastoid surgery. Materials and methods: A total of 50 patients between the ages 25 to 45. years were divided into two groups as per the anaesthetic techniques used; nerve block group (N) and intravenous morphine group (M). After induction of general anaesthesia and before surgical incision: Group N patients (nerve block group) were given Great Auricular Nerve (GAN) and Auriculo-Temporal Nerve (ATN) block with 0.25% bupivacaine. Group M patients (morphine group) received 0.1. mg/kg morphine. In the post anaesthesia care unit (PACU), Visual Analogue Scale (VAS) was used to assess post operative pain, Ramsay Sedation Scale (RSS) for sedation and post operative nausea and vomiting (PONV) impact scale score. Results: VAS scores and requirement of rescue analgesics in the PACU was significantly less in the N Group for first 3. h. The group N patients had a less frequent incidence of vomiting requiring intervention and were ready to be discharged from hospital after 3. h of surgery. Conclusion: Combination of GAN and ATN block with general anaesthesia is an uncomplicated, effective and well tolerated method for the safe conduct of mastoid surgery.

There are different anatomical situations inside the nasal cavity leading to rhinogenic contact point headache (RCPH), where each contact point has its own characteristics. The precise excision of contact points by endoscopic approach in patients with RCPH is very effective and could be done carefully in selected patients. This review presents an overview of the current aspects in pathophysiology, clinical profile, and management of RCPH.

Objective Paediatric rigid bronchoscopy is always a challenging situation for anaesthetist and surgeon. Maintaining adequate ventilation and oxygenation is difficult as pulmonary gas exchange is reduced due to obstruction of airway by foreign body (FB). This study evaluates safe and effective anaesthesia during paediatric rigid bronchoscopy. Study design A retrospective study. Methods We report a study of nine children who had undergone rigid bronchoscopy by use of spontaneous ventilation with fentanyl, propofol, dexamethasone, midazolam and sevoflurane without the use of muscle relaxant. Results Fentanyl, propofol, dexamethasone, midazolam and sevoflurane can be safely used in paediatric rigid bronchoscopy. No side effects are seen during and after the procedure. Conclusion Spontaneous ventilation is usually the preferred method where propofol is combined with midazolam, fentanyl, dexamethasone and sevoflurane for safe and effective anaesthesia in children for rigid bronchoscopy.