Sharma Yk’s scientific contributions

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Publications (2)


Table 1 : Effect of Therapy on Criterias of Assessment
A CLINICAL STUDY TO EVALUATE THE BOWEL REGULATORY POTENTIAL OF SHRIPHALADI KHANDA-AN AYURVEDIC FORMULATION
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February 2015

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582 Reads

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Sharma Yk

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Manglesh Rajesh

Lifestyle of humans has changed substantially in this modernized world. Technology has given easy access to almost everything under our fingers, but has led to reduced physical activity leading to increased incidence of lifestyle related disorders. Recent trends have shown people taking high amount of calories from animal products, sugars, fats & refined food items. Consumption of fibers in the diet has reduced. Young generation is more into the habit of junk food. Further level of stress has increased both at personal and professional life. All these factors are having ill effects on every organ system of body. Due to these lifestyle changes gastrointestinal symptoms like constipation, heartburn, abdominal discomfort & diarrhea are frequently encountered in clinical practice. Constipation is a common prevalent problem in general population with prevalence 2-28%. Constipation is associated with significantly impaired quality of life and psychological distress, as well as increased health care costs and impaired work productivity. Constipation has been defined as a frequency of defecation less than three times per week with subjective complaints of excessive straining, hard stools, lower abdominal fullness and a sense of incomplete evacuation. Different classes of laxatives have various limitations in one or another form. Hence present study was planned to evaluate the bowel regulatory potential of a herbal formulation Shriphaladi khanda. The trial drug was found to be an effective, clinically safe and non habit forming herbal formulation with good palatability.

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Clinical Evaluation of Shilajatu in Diabetes Mellitus

January 2015

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2,435 Reads

The incidence of diabetes mellitus is increasing rapidly because of changes in dietetic habits and life style. Continuous research is being done by scientists of various fields in order to achieve an effective cure of the disease. A great deal of work has also been done by Ayurvedic research scholars on various herbal and mineral drugs to find an effective treatment for Prameha. Shilajatu is one such drug which has been described for the management of Prameha in Ayurveda texts. The present study was conducted to clinically assess the efficacy of Shilajatu in the management of Prameha. Twenty two diabetic patients were selected for the study. The results were assessed in terms of symptomatic relief on the basis of scoring system, laboratory investigations including fasting blood glucose, post prandial blood glucose, glycosylated Hb, urine sugar, and a Questionnaire on Quality of Life. Statistically highly significant improvement (p <0.001) was observed on FBS and PPBS. Statistically significant improvement was observed on urine sugar and glycosylated haemoglobin with p <0.05 and p<0.01 respectively. In terms of subjective parameters also, highly significant improvement, with p <0.001 was observed in Shaithilya, Mukha Sosha, Sandhi Shoola, Prabhuta Mutrata, Pipasa and Kshudha. Highly significant improvement was observed in quality of life statistically with p <0.001. The study revealed that Shilajatu can be used as a drug in the management of Prameha.