Seema Rai's research while affiliated with Manipal Academy of Higher Education and other places

Publications (5)

Article
Improved antioxidant status helps to minimize the oxidative damage and thus can delay the risk of developing many chronic age related, free radical induced damage in diseases like diabetes, cancer, neurodegenerative diseases. We tried to evaluate the antioxidant potential of Costus igneus (CI) leaves in ethanol induced peroxidative damage in albino...
Article
Full-text available
Mucuna pruriens commonly known as cowhage plant has been claimed to possess various beneficial effects like anti-parkinsonian, anti-tumor, neuroprotective, antioxidant, anti-diabetic and antidepressant activities. Previous studies have reported that Mucuna pruriens contains L-DOPA and 5-hydroxy tryptophan (5-HT) as a major constituent with higher c...
Article
Objectives: To evaluate the acute oral toxicity of VTH pills in wistar rats Methods: The study was conducted in two phases: initial and continuation phase. In the initial phase there were two groups: control and test, with ten rats (5 male and 5 female) in each group. The control group received 2% gum acacia (vehicle) 10mg/kg; the test group receiv...
Article
Full-text available
Objectives: To evaluate the acute oral toxicity of VTH pills in wistar rats Methods: The study was conducted in two phases: initial and continuation phase. In the initial phase there were two groups: control and test, with ten rats (5 male and 5 female) in each group. The control group received 2% gum acacia (vehicle) 10mg/kg; the test group receiv...

Citations

... Mucuna pruriens L. (MP) has stood out among herbal medicines as a possible alternative for treating obesity, since it has a rich nutritional composition, 19,20 in addition to hypoglycemic, 21 hypolipidemic, 22 antioxidant, 23 anti-inflammatory 24 and anxiolytic effects. 25 However, such effects of MP have been reported in the literature in non-obese animals and humans, and our research group recently demonstrated weight loss, anxiolytic and antidepressant effects of MP in obese rats 16 for the first time in the literature. Considering the possible influence of MP treatment on the intestine-brain axis of obese rats, this study aimed to assess consumption and food preference, intestinal health, and somatic, biochemical and histological parameters of obese rats treated with MP. ...