Satya Nath Doley’s research while affiliated with Gauhati University and other places

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Publications (2)


(Print) www.rjptonline.org 0974-360X (Online) Antibacterial Evaluation of some traditionally used medicinal plants and their Formulations for treatment of Gastro Intestinal Disorders
  • Article
  • Full-text available

June 2023

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148 Reads

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1 Citation

Research Journal of Pharmacy and Technology

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Even though modern medicinal system is well developed and easily accessible, the rural people still continues to depend upon traditional medicinal system for curing various ailments. Several cases of fast recovery and many cases of death due to wrong treatment was observed during the year 2018-19 in rural villages of Nagaon district of Assam, India. The objective of this study was to evaluate the efficacy of some medicinal plants and their formulations used by traditional healer for treatment of gastrointestinal disorders. The information was collected by interaction with the traditional healers and altogether 14 plant species were documented for preparation of six different formulations. Antibacterial evaluation against E. coli, P. aeruginosa and S. aureus revealed that formulation prepared from freshly prepared plant materials showed better efficacy than formulations obtained from traditional healers. Again, organic solvents extracts showed greater antibacterial activity than the aqueous extracts. Amongst the solvents, the polar organic solvent methanol showed greater inhibitory effect as compared to other non polar organic solvents, ethanol and hexane. GC-MS analysis of the potent plant extracts showed presence of several bioactive compounds like tumerone, curlone, hexadecanoic acid, oleic acid, eicosanoic acid, erucic acid and isopimaric acid which have earlier reports of having significant antibacterial activities.

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Growth of Pleurotus ostreatus on different substrates (a) T1 = rice straw, (b) T2 = sugarcane bagasse, (c) T3 = wood chips, (d) T4 = wood flakes, (e) T5 = citronella bagasse (Cymbopogon nardus), (f) T6 = sawdust, (g) T7 = leaf litter (Monoon longifolium), (h) T8 = rice straw + sugarcane bagasse (50% + 50%), (i) T9 = rice straw + wood chips (60% + 40%), (j) T10 = wood flakes + sawdust (50% + 50%), (k) T11 = wood flakes + sugarcane bagasse (80% + 20%), (l) T12 = wood flakes + sugarcane bagasse + woodchips (35% + 35% + 30%), (m−n) T13 = rice straw + wood flakes + sawdust (50% + 40% + 10%), and T14 = Citronella bagasse + sugarcane bagasse + wood flakes + wood chips (25% each).
Effect of substrates on the mycelial growth of Pleurotus ostreatus. Treatments followed with the same letter are not significantly different by LSD (Least Significance Difference) test at a 5% level of significance.
Effect of different substrates and substrate combinations on yield of Pleurotus ostreatus. Treatments followed with the same letter are not significantly different by LSD (Least Significance Difference) test at a 5% level of significance.
Evaluation of different lignocellulosic-wastes and their combinations on growth and yield of Oyster mushroom (Pleurotus ostreatus)

April 2023

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363 Reads

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2 Citations

Studies in fungi

Lignocellulose wastes are generated in huge amounts by various sectors like agriculture, forestry, and industry but only a small portion of these wastes are utilized and a major portion is left unused. In this study, seven different lignocellulosic wastes and their combinations in different percentages were determined for the growth and yield of Pleurotus ostreatus. The maximum growth and yield of P. ostreatus were observed on a substrate made of rice straw, with a total yield of 399.70 gm per kg of substrate. The least growth and yield were recorded on a substrate made of wood flakes and sugarcane bagasse (80% + 20%), with a total yield of 13.54 gm per kg of substrate. Rice straw showed the highest biological efficiency (B.E) of 39.40, whereas wood flakes and sugarcane bagasse (80% + 20%) had the lowest B.E. of 1.35. Other substrates had a moderate effect, and citronella bagasse (Cymbopogon nardus), which was used as a substrate for the first time, gave a biological efficiency of 39.39 gm per kg substrate. The results showed a significant effect of substrates on mean yield and biological efficiency. Our study revealed that lignocellulosic waste can be profitably utilized for mushroom cultivation and could be one of the most economical and eco-friendly techniques.