Sarah N. Evanega’s research while affiliated with Cornell University and other places

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (1)


FIGURE 1 | Climate change will negatively impact food systems.
FIGURE 2 | Gene editing improvements for land sparing in orange, nutrition in blue, abiotic stress tolerance in red, and disease in green. (A,B) MSTN gene edits in livestock enhance muscle yields in a variety of organisms. (B) CRISPR/Cas9 mediated MSTN edited red sea bream (left) and wild type (right) (Kishimoto et al., 2018). Edited red sea bream exhibited 16% skeletal muscle mass increases on average. (C) TALEN enabled MSTN edited cow (right) and wild type (left) exhibit increased overall mass and greater muscle mass (Proudfoot et al., 2015). (C) CRISPR/Cas9 promoter editing of tomato CLV3, S, SP facilitated novel variation and enhancements to fruit size, floral architecture and overall architecture in tomato. Edited tomato (right) exhibits enlarged fruit size and increased locule number (Rodríguez-Leal et al., 2017). (D) CRISPR/Cas9 edited LCYε enhanced beta-carotene accumulation in edited banana (right) relative to wild type (left) by nearly six fold in some lines (Kaur et al., 2020). (E) CRISPR/Cas9 mediated editing of G0S2 in chicken (right) accumulates less abdominal and gastrointestinal fat (Park et al., 2019). (F) Improvements to saline tolerance in rice. Knockout of OsRR22 enhances yield in high saline environments. Wild type (left) and edited rice (right) grown in 0.75% saline solution. Wild type plants are 13% shorter than edited plants in saline conditions (Zhang A. et al., 2019). (G) CD163 locus edited by CRISPR/Cas9 yielded gene edited pigs that are entirely resistant to porcine reproductive and respiratory virus when challenged with the virus (Whitworth et al., 2014, 2016). (H) bsr-k1 edited rice in field (right) greatly outperforms wild type (left) after being challenged with rice blast. Edited lines performed 50% better than wild type in field after inoculation (Zhou X. et al., 2018).
FIGURE 3 | Overview of gene editing innovation emergence over time and species. (A) Annual count of gene editing innovations since 2009. (B) Proportion of gene editing innovations (B) in crops and livestock (C) a diverse array of crops (D) a diverse array of livestock.
Summary of gene-editing applications for abiotic stress.
Summary of gene-editing applications for disease tolerance.

+2

Application of Gene Editing for Climate Change in Agriculture
  • Article
  • Full-text available

September 2021

·

746 Reads

·

111 Citations

Nicholas G. Karavolias

·

Wilson Horner

·

·

Sarah N. Evanega

Climate change imposes a severe threat to agricultural systems, food security, and human nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to improve performance across a range of traits. Many of the targeted phenotypes include attributes that could be beneficial for climate change adaptation. Here, we present examples of emerging gene editing applications and research initiatives that are aimed at the improvement of crops and livestock in response to climate change, and discuss technical limitations and opportunities therein. While only few applications of gene editing have been translated to agricultural production thus far, numerous studies in research settings have demonstrated the potential for potent applications to address climate change in the near future.

Download

Citations (1)


... Studies have explored these concerns, suggesting that with appropriate regulatory and monitoring regimes, the negative effects can be minimized, thus allowing the benefits of GMOs to be harnessed without compromising safety and environmental integrity [46]. In the 2020s, a new "gene revolution," whereby DNA can be genetically edited without splicing in genes from a separate organism, so-called "genome-editing", has emerged to enhance the resilience and nutritional content of various crops, by combatting biotic and abiotic stresses, helping mitigate the effects of climate change on agriculture [47]. The potential benefits of gene-edited crops include higher yields, improved resistance to pests and pathogens, and reduced reliance on pesticides. ...

Reference:

Getting (ECO)Ready: Does EU Legislation Integrate Up-to-Date Scientific Data for Food Security and Biodiversity Preservation Under Climate Change?
Application of Gene Editing for Climate Change in Agriculture