Sarah Karimnia’s research while affiliated with Johannes Gutenberg University Mainz and other places

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Publications (8)


Genetische Analyse der Skelette der Rondellanlage von Pömmelte-Zackmünde, Sachsen-Anhalt
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July 2019

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12 Reads

Sarah Karimnia

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Der Erfolg molekulargenetischer Untersuchungen an archäologischen Skelettresten ist maßgeblich von der Erhaltung der menschlichen Überreste abhängig. Trotz schlechter Knochenerhaltung wurden im Fall von Pömmelte-Zackmünde an vier Individuen aDNA-Analysen durchgeführt. Die vorläufigen Ergebnisse belegen zwar für alle Individuen die gleiche mitochondriale Haplogruppe U, ließen sich jedoch nicht näher eingrenzen bzw. unabhängig reproduzieren. Mit den in den letzten Jahren entwickelten neuen Methoden wird dies ggf. in Zukunft noch gelingen.

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Eine Neunfachbestattung der Salzmünder Kultur am eponymen Fundplatz Salzmünde

December 2017

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1,206 Reads

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2 Citations

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Christian Meyer

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Björn Schlenker

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[...]

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Susanne Friederich

Lombards on the Move – An Integrative Study of the Migration Period Cemetery at Szólád, Hungary

November 2014

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4,032 Reads

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81 Citations

In 2005 to 2007 45 skeletons of adults and subadults were excavated at the Lombard period cemetery at Szólád (6th century A.D.), Hungary. Embedded into the well-recorded historical context, the article presents the results obtained by an integrative investigation including anthropological, molecular genetic and isotopic (δ15N, δ13C, 87Sr/86Sr) analyses. Skeletal stress markers as well as traces of interpersonal violence were found to occur frequently. The mitochondrial DNA profiles revealed a heterogeneous spectrum of lineages that belong to the haplogroups H, U, J, HV, T2, I, and K, which are common in present-day Europe and in the Near East, while N1a and N1b are today quite rare. Evidence of possible direct maternal kinship was identified in only three pairs of individuals. According to enamel strontium isotope ratios, at least 31% of the individuals died at a location other than their birthplace and/or had moved during childhood. Based on the peculiar 87Sr/86Sr ratio distribution between females, males, and subadults in comparison to local vegetation and soil samples, we propose a three-phase model of group movement. An initial patrilocal group with narrower male but wider female Sr isotope distribution settled at Szólád, whilst the majority of subadults represented in the cemetery yielded a distinct Sr isotope signature. Owing to the virtual absence of Szólád-born adults in the cemetery, we may conclude that the settlement was abandoned after approx. one generation. Population heterogeneity is furthermore supported by the carbon and nitrogen isotope data. They indicate that a group of high-ranking men had access to larger shares of animal-derived food whilst a few individuals consumed remarkable amounts of millet. The inferred dynamics of the burial community are in agreement with hypotheses of a highly mobile lifestyle during the Migration Period and a short-term occupation of Pannonia by Lombard settlers as conveyed by written sources.



Fig. 2. Ward clustering, genetic distances, and test of population continuity. Haplogroup frequencies of HGC, the nine Mittelelbe-Saale cultures (see Fig. 1 for abbreviations), and a CEM (n = 500) (table S5) were used for hierarchical Ward clustering (A). Cluster significance is given as percent of reproduced clusters on 10,000 bootstrap replicates. We computed genetic distances (F st ) (table S6) on the basis of HVS-I sequences (nucleotide position 16,059 to 16,400) between all cultures (B) and pools of Early/Middle and Late Neolithic/EBA cultures (C). The shading indicates the degree of genetic distance between the cultures ranging from white (small distances and high similarities) to green (large distances and dissimilarities). Significant differences are indicated by + (after 10,000 permutations and post-hoc Benjamini-Hochberg correction) (table S6). The upper diagonal (D) summarizes the results of the test of population continuity to evaluate possible effects of genetic drift. The P values (table S8) describe the probability that changes in haplogroup frequencies between two populations cannot be explained by genetic drift alone [white areas, nonsignificant; green areas, significant (13)]. 
Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity

October 2013

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2,029 Reads

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401 Citations

Science

The processes that shaped modern European mitochondrial DNA (mtDNA) variation remain unclear. The initial peopling by Palaeolithic hunter-gatherers ~42,000 years ago and the immigration of Neolithic farmers into Europe ~8000 years ago appear to have played important roles but do not explain present-day mtDNA diversity. We generated mtDNA profiles of 364 individuals from prehistoric cultures in Central Europe to perform a chronological study, spanning the Early Neolithic to the Early Bronze Age (5500 to 1550 calibrated years before the common era). We used this transect through time to identify four marked shifts in genetic composition during the Neolithic period, revealing a key role for Late Neolithic cultures in shaping modern Central European genetic diversity.




Citations (4)


... The application of the mass grave definition excludes many other burial contexts with multiple individuals that may also reflect the sudden death of several people in a short period of time, due to devastating events such as infectious diseases or famine. Multiple burials are in general more often known from the later Neolithic periods, for example, from Corded Ware (final Neolithic) or Salzmünde contexts (late Neolithic) (Alt et al., 2017;Dresely, 2004). One exception is the multiple grave located in the vicinity of the Michelsberg earthwork Bruchsal-Aue (4250-3650 cal. ...

Reference:

Infectious diseases and Neolithic transformations: Evaluating biological and archaeological proxies in the German loess zone between 5500 and 2500 BCE
Eine Neunfachbestattung der Salzmünder Kultur am eponymen Fundplatz Salzmünde

... We also sequenced reads of a capture set consisting 3,000 nuclear single nucleotide polymorphisms (SNPs; see Materials and Methods) and whole mitochondrial DNAs (mtDNAs) of all individuals. The shotgun-and the capture-sequenced samples ultimately resulted in an average ∼144k SNPs/individual using the 1240k SNP panel for genotype calling (Mathieson et al. 2015 Sr/ 86 Sr isotope analyses; the latter is routinely used to trace individual mobility (Alt et al. 2014). ...

Lombards on the Move – An Integrative Study of the Migration Period Cemetery at Szólád, Hungary

... In examinations of mass graves, the identification of perimortem injuries, besides age and sex of the dead, also plays an important role in the interpretation of the overall feature, since (natural) catastrophes or epidemics can also lead to large numbers of bodies being buried simultaneously [68][69][70]. In cases where the mass grave is linked to an historically documented battle, information regarding injury types and patterns can assist in reconstructing the course of the battle and the nature of the specific warfare (e.g. ...

Eine komplexe Mehrfachbestattung der Salzmünder Kultur.

... This problem does not affect the work reported here, because we use only ancient genetic data. Haplogroup studies using ancient DNA have yielded very important and sound observations, such as a clear genetic discontinuity between local HGs and the first farmers in central Europe 24 , a resurgence of HG lineages during the middle Neolithic in the same region 25 , etc. Moreover, the usefulness of single genetic markers has been shown by several recent ancient DNA studies, for example, analyzing mt haplogroup K 20 and Y-chromosome haplogroup H2 26 in the Early Neolithic, mt haplogroup H in the Middle and Late Neolithic 27 , mt haplogroups A2 and C1 in pre-contact Caribbean islanders 28 , etc. ...

Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity

Science