# Santiago Segarra's research while affiliated with Rice University and other places

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## Publications (176)

We develop a theory of limits for sequences of dense abstract simplicial complexes, where a sequence is considered convergent if its homomorphism densities converge. The limiting objects are represented by stacks of measurable [0,1]-valued functions on unit cubes of increasing dimension, each corresponding to a dimension of the abstract simplicial...

This paper looks at the task of network topology inference, where the goal is to learn an unknown graph from nodal observations. One of the novelties of the approach put forth is the consideration of prior information about the density of motifs of the unknown graph to enhance the inference of classical Gaussian graphical models. Dealing with the d...

We develop a framework for incorporating edge-dependent vertex weights (EDVWs) into the hypergraph minimum s - t cut problem. These weights are able to reflect different importance of vertices within a hyperedge, thus leading to better characterized cut properties. More precisely, we introduce a new class of hyperedge splitting functions that we ca...

The COVID-19 pandemic has emphasized the importance of accurate detection of known and emerging pathogens. However, robust characterization of pathogenic sequences remains an open challenge. To address this need we developed SeqScreen, which accurately characterizes short nucleotide sequences using taxonomic and functional labels and a customized s...

Characterizing metagenomes via kmer-based, database-dependent taxonomic classification has yielded key insights into underlying microbiome dynamics. However, novel approaches are needed to track community dynamics and genomic flux within metagenomes, particularly in response to perturbations. We describe KOMB, a novel method for tracking genome lev...

Solving the optimal symbol detection problem in multiple-input multiple-output (MIMO) systems is known to be NP-hard. Hence, the objective of any detector of practical relevance is to get reasonably close to the optimal solution while keeping the computational complexity in check. In this work, we propose a MIMO detector based on an annealed versio...

Higher-order networks have so far been considered primarily in the context of studying the structure of complex systems, i.e., the higher-order or multi-way relations connecting the constituent entities. More recently, a number of studies have considered dynamical processes that explicitly account for such higher-order dependencies, e.g., in the co...

Distributed scheduling algorithms for throughput or utility maximization in dense wireless multi-hop networks can have overwhelmingly high overhead, causing increased congestion, energy consumption, radio footprint, and security vulnerability. For wireless networks with dense connectivity, we propose a distributed scheme for link sparsification wit...

Optimal symbol detection in multiple-input multiple-output (MIMO) systems is known to be an NP-hard problem. Hence, the objective of any detector of practical relevance is to get reasonably close to the optimal solution while keeping the computational complexity in check. In this work, we propose a MIMO detector based on an annealed version of Lang...

Graph filtering is the cornerstone operation in graph signal processing (GSP). Thus, understanding it is key in developing potent GSP methods. Graph filters are local and distributed linear operations, whose output depends only on the local neighborhood of each node. Moreover, a graph filter's output can be computed separately at each node by carry...

We consider the problem of estimating the topology of multiple networks from nodal observations, where these networks are assumed to be drawn from the same (unknown) random graph model. We adopt a graphon as our random graph model, which is a nonparametric model from which graphs of potentially different sizes can be drawn. The versatility of graph...

We develop a novel graph-based trainable framework to maximize the weighted sum energy efficiency (WSEE) for power allocation in wireless communication networks. To address the non-convex nature of the problem, the proposed method consists of modular structures inspired by a classical iterative suboptimal approach and enhanced with learnable compon...

We develop a framework for incorporating edge-dependent vertex weights (EDVWs) into the hypergraph minimum s-t cut problem. These weights are able to reflect different importance of vertices within a hyperedge, thus leading to better characterized cut properties. More precisely, we introduce a new class of hyperedge splitting functions that we call...

We propose a data-driven approach for power allocation in the context of federated learning (FL) over interference-limited wireless networks. The power policy is designed to maximize the transmitted information during the FL process under communication constraints, with the ultimate objective of improving the accuracy and efficiency of the global F...

In wireless multi-hop networks, delay is an important metric for many applications. However, the max-weight scheduling algorithms in the literature typically focus on instantaneous optimality, in which the schedule is selected by solving a maximum weighted independent set (MWIS) problem on the interference graph at each time slot. These myopic poli...

Power allocation is one of the fundamental problems in wireless networks and a wide variety of algorithms address this problem from different perspectives. A common element among these algorithms is that they rely on an estimation of the channel state, which may be inaccurate on account of hardware defects, noisy feedback systems, and environmental...

Optimal symbol detection in multiple-input multiple-output (MIMO) systems is known to be an NP-hard problem. Recently, there has been a growing interest to get reasonably close to the optimal solution using neural networks while keeping the computational complexity in check. However, existing work based on deep learning shows that it is difficult t...

The Word Adjacency Network (WAN) method is a newly invented method for attributing the authorship of texts based on internal evidence about the proximities of high-frequency words in those texts. The method has been the subject of mathematically rigorous explanations in scientific journals and here is offered instead a relatively non-technical acco...

Graph neural networks (GNNs) have achieved superior performance on node classification tasks in the last few years. Commonly, this is framed in a transductive semi-supervised learning setup wherein the entire graph, including the target nodes to be labeled, is available for training. Driven in part by scalability, recent works have focused on the i...

Particle filtering is used to compute good nonlinear estimates of complex systems. It samples trajectories from a chosen distribution and computes the estimate as a weighted average. Easy-to-sample distributions often lead to degenerate samples where only one trajectory carries all the weight, negatively affecting the resulting performance of the e...

Learning graphs from sets of nodal observations represents a prominent problem formally known as graph topology inference. However, current approaches are limited by typically focusing on inferring single networks, and they assume that observations from all nodes are available. First, many contemporary setups involve multiple related networks, and...

Graph convolutional neural networks (GCNNs) are popular deep learning architectures that, upon replacing regular convolutions with graph filters (GFs), generalize CNNs to irregular domains. However, classical GFs are prone to numerical errors since they consist of high-order polynomials. This problem is aggravated when several filters are applied i...

A fundamental problem in signal processing is to denoise a signal. While there are many well-performing methods for denoising signals defined on regular supports, such as images defined on two-dimensional grids of pixels, many important classes of signals are defined over irregular domains such as graphs. This paper introduces two untrained graph n...

We develop wavelet representations for edge-flows on simplicial complexes, using ideas rooted in combinatorial Hodge theory and spectral graph wavelets. We first show that the Hodge Laplacian can be used in lieu of the graph Laplacian to construct a family of wavelets for higher-order signals on simplicial complexes. Then, we refine this idea to co...

We study the problem of optimal power allocation in single-hop multi-antenna ad-hoc wireless networks. A standard technique to solve this problem involves optimizing a tri-convex function under power constraints using a block-coordinate-descent (BCD) based iterative algorithm. This approach, termed WMMSE, tends to be computationally complex and tim...

Efficient scheduling of transmissions is a key problem in wireless networks. The main challenge stems from the fact that optimal link scheduling involves solving a maximum weighted independent set (MWIS) problem, which is known to be NP-hard. For practical link scheduling schemes, centralized and distributed greedy heuristics are commonly used to a...

We provide a complete taxonomic characterization of robust hierarchical clustering methods for directed networks following an axiomatic approach. We begin by introducing three practical properties associated with the notion of robustness in hierarchical clustering: linear scale preservation, stability, and excisiveness. Linear scale preservation en...

We consider the problem of estimating a network's eigenvector centrality only from data on the nodes, with no information about network topology. Leveraging the versatility of graph filters to model network processes, data supported on the nodes is modeled as a graph signal obtained via the output of a graph filter applied to white noise. We seek t...

Higher-order networks have so far been considered primarily in the context of studying the structure of complex systems, i.e., the higher-order or multi-way relations connecting the constituent entities. More recently, a number of studies have considered dynamical processes that explicitly ac- count for such higher-order dependencies, e.g., in the...

Key to successfully deal with complex contemporary datasets is the development of tractable models that account for the irregular structure of the information at hand. This paper provides a comprehensive and unifying view of several sampling, reconstruction, and recovery problems for signals defined on irregular domains that can be accurately repre...

Contemporary data is often supported by an irregular structure, which can be conveniently captured by a graph. Accounting for this graph support is crucial to analyze the data, leading to an area known as graph signal processing (GSP). The two most important tools in GSP are the graph shift operator (GSO), which is a sparse matrix accounting for th...

Key to successfully deal with complex contemporary datasets is the development of tractable models that account for the irregular structure of the information at hand. This paper provides a comprehensive view of several sampling, reconstruction, and recovery problems for signals defined on irregular domains that can be accurately represented by a g...

With the increasing popularity of graph-based methods for dimensionality reduction and representation learning, node embedding functions have become important objects of study in the literature. In this paper, we take an axiomatic approach to understanding node embedding methods, first stating three properties for embedding dissimilarity networks,...

A widely established set of unsupervised node embedding methods can be interpreted as consisting of two distinctive steps: i) the definition of a similarity matrix based on the graph of interest followed by ii) an explicit or implicit factorization of such matrix. Inspired by this viewpoint, we propose improvements in both steps of the framework. O...

Modern benchtop DNA synthesis techniques and increased concern of emerging pathogens have elevated the importance of screening oligonucleotides for pathogens of concern. However, accurate and sensitive characterization of oligonucleotides is an open challenge for many of the current techniques and ontology-based tools. To address this gap, we have...

In this tutorial, we provide a didactic treatment of the emerging topic of signal processing on higher-order networks. Drawing analogies from discrete and graph signal processing, we introduce the building blocks for processing data on simplicial complexes and hypergraphs, two common higher-order network abstractions that can incorporate polyadic r...

We study the problem of optimal power allocation in a single-hop ad hoc wireless network. In solving this problem, we depart from classical purely model-based approaches and propose a hybrid method that retains key modeling elements in conjunction with data-driven components. More precisely, we put forth a neural network architecture inspired by th...

Graph search is one of the most successful algorithmic trends in near neighbor search. Several of the most popular and empirically successful algorithms are, at their core, a simple walk along a pruned near neighbor graph. Such algorithms consistently perform at the top of industrial speed benchmarks for applications such as embedding search. Howev...

The graph convolutional network (GCN) is a go-to solution for machine learning on graphs, but its training is notoriously difficult to scale in terms of both the size of the graph and the number of model parameters. These limitations are in stark contrast to the increasing scale (in data size and model size) of experiments in deep learning research...

We consider the construction of neural network architectures for data on simplicial complexes. In studying maps on the chain complex of a simplicial complex, we define three desirable properties of a simplicial neural network architecture: namely, permutation equivariance, orientation equivariance, and simplicial awareness. The first two properties...

We propose a novel method to co-cluster the vertices and hyperedges of hypergraphs with edge-dependent vertex weights (EDVWs). In this hypergraph model, the contribution of every vertex to each of its incident hyperedges is represented through an edge-dependent weight, conferring the model higher expressivity than the classical hypergraph. In our m...

This tutorial paper presents a didactic treatment of the emerging topic of signal processing on higher-order networks. Drawing analogies from discrete and graph signal processing, we introduce the building blocks for processing data on simplicial complexes and hypergraphs, two common abstractions of higher-order networks that can incorporate polyad...

We provide a complete taxonomic characterization of robust hierarchical clustering methods for directed networks following an axiomatic approach. We begin by introducing three practical properties associated with the notion of robustness in hierarchical clustering: linear scale preservation, stability, and excisiveness. Linear scale preservation en...

Using graphs to model irregular information domains is an effective approach to deal with some of the intricacies of contemporary (network) data. A key aspect is how the data, represented as graph signals, depend on the topology of the graph. Widely-used approaches assume that the observed signals can be viewed as outputs of graph filters (i.e., po...

Background
Sudden unexpected death in epilepsy (SUDEP) is a leading cause of premature death in patients with epilepsy. If timely assessment of SUDEP risk can be made, early interventions for optimized treatments might be provided. One of the biomarkers being investigated for SUDEP risk assessment is postictal generalized EEG suppression [postictal...

We study the role of the constraint set in determining the solution to low-rank, positive semidefinite (PSD) matrix sensing problems. The setting we consider involves rank-one sensing matrices: In particular, given a set of rank-one projections of an approximately low-rank PSD matrix, we characterize the radius of the set of PSD matrices that satis...

We study the problem of adaptive contention window (CW) design for random-access wireless networks. More precisely, our goal is to design an intelligent node that can dynamically adapt its minimum CW (MCW) parameter to maximize a network-level utility knowing neither the MCWs of other nodes nor how these change over time. To achieve this goal, we a...

We study the temporal reconstruction of epidemics evolving over networks. Given partial or aggregated temporal information of the epidemic, our goal is to estimate the complete evolution of the spread leveraging the topology of the network but being agnostic to the precise epidemic model. We overcome this lack of model awareness through a data-driv...

A fundamental problem in the design of wireless networks is to efficiently schedule transmission in a distributed manner. The main challenge stems from the fact that optimal link scheduling involves solving a maximum weighted independent set (MWIS) problem, which is NP-hard. For practical link scheduling schemes, distributed greedy approaches are c...

We study the problem of optimal power allocation in a single-hop ad hoc wireless network. In solving this problem, we propose a hybrid neural architecture inspired by the algorithmic unfolding of the iterative weighted minimum mean squared error (WMMSE) method, that we denote as unfolded WMMSE (UWMMSE). The learnable weights within UWMMSE are param...

This article provides an overview of the current landscape of signal processing (SP) on directed graphs (digraphs). Directionality is inherent to many real-world (information, transportation, biological) networks, and it should play an integral role in processing and learning from network data. We thus lay out a comprehensive review of recent advan...

We consider the problem of sequential graph topology change-point detection from graph signals. We assume that signals on the nodes of the graph are regularized by the underlying graph structure via a graph filtering model, which we then leverage to distill the graph topology change-point detection problem to a subspace detection problem. We demons...

Inferring graph structure from observations on the nodes is an important and popular network science task. Departing from the more common inference of a single graph and motivated by social and biological networks, we study the problem of jointly inferring multiple graphs from the observation of signals at their nodes (graph signals), which are ass...

We consider the problem of inferring the unobserved edges of a graph from data supported on its nodes. In line with existing approaches, we propose a convex program for recovering a graph Laplacian that is approximately diagonalizable by a set of eigenvectors obtained from the second-order moment of the observed data. Unlike existing work, we incor...

We study the problem of optimal power allocation in a single-hop ad hoc wireless network. In solving this problem, we depart from classical purely model-based approaches and propose a hybrid method that retains key modeling elements in conjunction with data-driven components. More precisely, we put forth a neural network architecture inspired by th...

We consider the problem of estimating a network's eigenvector centrality only from data on the nodes, with no information about network topology. Leveraging the versatility of graph filters to model network processes, data supported on the nodes is modeled as a graph signal obtained via the output of a graph filter applied to white noise. We seek t...

Networks and data supported on graphs have become ubiquitous in the sciences and engineering. This paper studies the 'blind' community detection problem, where we seek to infer the community structure of a graph model given the observation of independent graph signals on a set of nodes whose connections are unknown. We model each observation as fil...

This paper provides an overview of the current landscape of signal processing (SP) on directed graphs (digraphs). Directionality is inherent to many real-world (information, transportation, biological) networks and it should play an integral role in processing and learning from network data. We thus lay out a comprehensive review of recent advances...

Background
Taxonomic classification of microbiomes has provided tremendous insight into the underlying genome dynamics of microbial communities but has relied on known microbial genomes contained in curated reference databases.
Methods
We propose K-core graph decomposition as a novel approach for tracking metagenome dynamics that is taxonomy-obliv...

This paper studies the problem of jointly estimating multiple network processes driven by a common unknown input, thus effectively generalizing the classical blind multi-channel identification problem to graphs. More precisely, we model network processes as graph filters and consider the observation of multiple graph signals corresponding to output...