Sandra R Merchant's research while affiliated with Louisiana State University and other places

Publications (7)

Article
Adverse food reactions (AFR) are a common problem that may cause cutaneous and/or gastrointestinal signs in dogs and cats. They comprise food intolerance, food intoxication, and food allergy. Response to a dietary elimination trial and recurrence of signs during dietary provocation remain the centerpiece of diagnosis and management of dogs and cats...
Article
Full-text available
The in vitro activity of 10 cephalosporin antimicrobial agents against 75 isolates of methicillin-susceptible Staphylococcus pseudintermedius derived from dogs was assessed. The lowest minimal inhibitory concentration for 90% of strains (MIC90) values obtained were for cephalothin, cefovecin, and cefazolin (0.12 ug/mL), followed by ceftiofur and ce...
Article
This double-blinded noninferiority clinical trial evaluated the use of oral fluconazole for the treatment of Malassezia dermatitis in dogs by comparing it with use of an accepted therapeutic agent, ketoconazole. Dogs presenting with Malassezia dermatitis were treated with either fluconazole or ketoconazole in addition to cephalexin for concurrent b...
Article
This study evaluated the middle ear microbial flora and antimicrobial susceptibility patterns from dogs with otitis media. Antimicrobial susceptibility patterns were obtained on 164 micro-organisms from 107 ears of 82 dogs with otitis media that presented to Louisiana State University over a 12-year period. The most common micro-organisms isolated...
Article
Skin biopsies are a viable diagnostic tool in avian dermatology, however, the thinness of avian skin makes it difficult to prevent rolling and contraction of skin biopsy specimens during collection and fixation. The difficulty orienting such rolled samples during processing ultimately interferes with the establishment of a histopathological diagnos...
Article
Draining tracts and nodules in the dog and cat can present a diagnostic challenge to the veterinarian. A systematic approach and a complete list of differential diagnoses are needed to define the underlying disease, so that appropriate therapeutic management can be instituted and prognosis can be discussed with the owner. The purpose of this articl...

Citations

... A low prevalence (4.2%) of P. aeruginosa was found in the urine of dogs suffering bladder infection, according to other authors which isolated Pseudomonas spp. in 2% [27], 1.3% [28], and 3.7% [29] of canine urinary tract infections. Instead, a discrete presence (32.6%) of P. aeruginosa was recorded in dogs with clinical signs of otitis, slightly higher if compared to the previous studies which reported a prevalence of 27% [30] and 23% [31]. Furthermore, in the skin and soft-tissue specimens, we found a higher prevalence of P. aeruginosa (15.4%) in comparison to the frequency isolation of 7.5% [30] and 10.6% [32] described by other studies. ...
... In the first phase of the study, 58 samples of pet food were analyzed and 46 of them were negative, while 12 samples (20.7% of total samples) showed a concentration level of histamine ranging from 1.5 to 30.1 mg/kg. The data are reported in Table 4. Chunks with tuna <LOQ [31] Mackerel with seaweed <LOQ [3] Chunks with tuna <LOQ [32] Tuna for kittens <LOQ [4] Minced tuna <LOQ [33] Sardines with shrimps <LOQ [5] Tuna <LOQ [34] Sardines with white fish <LOQ [6] With tuna 28.7 [35] Tuna with rice <LOQ [7] Tuna 29.6 [36] With tuna <LOQ [8] Tuna Japan style <LOQ [37] With tuna <LOQ [9] Tuna <LOQ [38] With tuna <LOQ [10] Pacific tuna in jelly <LOQ [39] Chunks with grilled tuna <LOQ [11] Tuna fillet in water and rice <LOQ [40] Tuna with mackerel <LOQ [12] Natural tuna <LOQ [41] Tuna with mackerel <LOQ [13] Chunks with trout 30.1 [42] Tuna <LOQ [14] Mackerel <LOQ [43] Savory cake with tuna <LOQ [15] Mousse with oceanic fish <LOQ [44] With tuna fillets and anchovies 4.3 [16] Tuna with rice <LOQ [45] Tuna <LOQ [17] Mackerel <LOQ [46] Tuna and vitamin premix <LOQ [18] Tonggol tuna fillet <LOQ [47] Tuna with aloe <LOQ [19] Skipjack tuna fillet <LOQ [48] Pacific tuna <LOQ [20] Tuna fillet and seaweed <LOQ [49] Tuna 13.3 [21] With tuna 1.5 [50] Tuna <LOQ [22] Pink tuna with mackerel <LOQ [51] Chunks with trout <LOQ [23] Pacific tuna with ocean fish 3.9 [52] Chunk with oceanic fish <LOQ [24] Pink tuna <LOQ [53] With tuna 20.2 [25] Tuna with rice and green beans <LOQ [54] With sardines in jelly 10.8 [26] Tuna with rice <LOQ [55] With tuna 11.9 [27] Tuna <LOQ [56] With mackerel in jelly with tomato <LOQ [28] Tuna with vegetables <LOQ [57] With tuna in sauce 2.3 [29] Mackerel in water <LOQ [58] With tuna fillets and anchovies <LOQ 1 As stated on the label on the basis of ingredients. How ingredients may be included in the product name depends on the percentage of that ingredient in the product and the use of certain descriptors. ...
... In non-MRSP isolates, a high proportion of isolates were susceptible to cephalosporins, which could be used as empirical treatment. Our findings have clinical relevance as amoxicillin-clavulanic acid and trimethoprim-sulfamethoxazole are considered as the first-choice antimicrobials for empirical UTI treatments of dogs (20), and cephalosporins are generally effective treatment options for Staphylococcus pseudintermedius infections (46). These findings highlight the importance of conducting an antimicrobial susceptibility test before starting UTI treatments. ...
... Due to its high concentration and persistence within the stratum corneum, pulse therapy of ITZ is used with 7 days on, 7 days off, 7 days on, or twice weekly administration [421,423]. Terbinafine [423][424][425][426] and FCZ [427] have been prescribed in single case reports and clinical trials are warranted before treatment recommendations can be made. Even if clinical evidence indicates the efficacy of azole for the control of skin infections, the common recurrence of skin disorders requires the recognition of underlying diseases or the use of prophylaxis systems for the management of these infections in animals [2]. ...
... Pentoxifylline (PTX) is a member of the class of drugs that inhibit nonselectively phosphodiesterase (PDE) enzymes, referred to as PDE inhibitors (Marks et al., 2001;Scott et al., 2001). It also decreases fibronectin, reduces the production of cytokines (tumor necrosis factor-alpha, interleukin-1, interleukin -6, and interleukin-8), decreases leukocyte response to interleukins, impairs T-lymphocyte binding to keratinocytes, decreases fibroblastic activity and with long-term use, may decrease fibrosis (Samlaska & Winfield, 1994;Bruyazeel et al., 1995). ...
... The terms fistula and draining tract are used to explain abnormal passages between internal organs or cavities, or leading from an organ or cavity to the skin (4,19,20). The differential diagnosis of fistula in dogs includes bacterial, fungal, and parasitic infections, as well as neoplastic changes, foreign bodies, and inflammatory and systemic conditions (11,24). A previous report showed that 15 of the 25 cases diagnosed as fistula were because of foreign bodies (19). ...
... Initially done to improve histopathological evaluation of avian skin that Use of translucent self-adhesive tape attached to skin biopsy sites before obtaining skin biopsies by using a standard skin biopsy punch instrument to prevent rolling and contraction of skin biopsy specimens during collection and fixation. (46) ...