Sandra R Merchant's research while affiliated with Louisiana State University and other places
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Publications (7)
Adverse food reactions (AFR) are a common problem that may cause cutaneous and/or gastrointestinal signs in dogs and cats. They comprise food intolerance, food intoxication, and food allergy. Response to a dietary elimination trial and recurrence of signs during dietary provocation remain the centerpiece of diagnosis and management of dogs and cats...
The in vitro activity of 10 cephalosporin antimicrobial agents against 75 isolates of methicillin-susceptible Staphylococcus pseudintermedius derived from dogs was assessed. The lowest minimal inhibitory concentration for 90% of strains (MIC90) values obtained were for cephalothin, cefovecin, and cefazolin (0.12 ug/mL), followed by ceftiofur and ce...
This double-blinded noninferiority clinical trial evaluated the use of oral fluconazole for the treatment of Malassezia dermatitis in dogs by comparing it with use of an accepted therapeutic agent, ketoconazole. Dogs presenting with Malassezia dermatitis were treated with either fluconazole or ketoconazole in addition to cephalexin for concurrent b...
This study evaluated the middle ear microbial flora and antimicrobial susceptibility patterns from dogs with otitis media. Antimicrobial susceptibility patterns were obtained on 164 micro-organisms from 107 ears of 82 dogs with otitis media that presented to Louisiana State University over a 12-year period. The most common micro-organisms isolated...
Skin biopsies are a viable diagnostic tool in avian dermatology, however, the thinness of avian skin makes it difficult to prevent rolling and contraction of skin biopsy specimens during collection and fixation. The difficulty orienting such rolled samples during processing ultimately interferes with the establishment of a histopathological diagnos...
Draining tracts and nodules in the dog and cat can present a diagnostic challenge to the veterinarian. A systematic approach and a complete list of differential diagnoses are needed to define the underlying disease, so that appropriate therapeutic management can be instituted and prognosis can be discussed with the owner. The purpose of this articl...
Citations
... Further cultivation of the isolated S. epidermidis on certain MSA media allowed for the isolation and identification of S. epidermidis. S. epidermidis was streaked on MSA, incubated at 37 • C for 24 h to determine colony appearance, and identified when a pink colony appeared on MSA [38], as shown in Figure 9. ...
Reference: antibiotics-11-01270-v2
... The disease is idiopathic, but genetic factors are thought to have a role in the development of CD (Verlinden et al. 2006). GSI has been seen in a small number of dogs, but not in cats (Gaschen & Merchant 2011). The diseased pups came from a single-family line of Irish Setters and a group of Border Terriers, and the ailment may be shown in puppies as young as three months old. ...
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... In non-MRSP isolates, a high proportion of isolates were susceptible to cephalosporins, which could be used as empirical treatment. Our findings have clinical relevance as amoxicillin-clavulanic acid and trimethoprim-sulfamethoxazole are considered as the first-choice antimicrobials for empirical UTI treatments of dogs (20), and cephalosporins are generally effective treatment options for Staphylococcus pseudintermedius infections (46). These findings highlight the importance of conducting an antimicrobial susceptibility test before starting UTI treatments. ...
... It has been demonstrated that M. pachydermatis isolates can become resistant during treatment with FLZ by inducing resistance in vitro to this antifungal [41]. Thus, the clinical utility of this azole in dogs and cats is questionable [8,42]. Bernardo et al. [43] found a M. pachydermatis isolate resistant to AMB. ...
... In dogs, the maximal plasma concentration can be obtained within 1 h after oral dosing. Humans have also experienced similar findings 34,35 . In our investigation, the PTX was loaded with Pluronic F127 gel and administered locally to the periphery of grafting. ...
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... It is important to note that this polymer is nonabsorbable; an absorbable implant might provide a reduced risk of late infection. 32 There are several limitations to this study. Assessment of the implant was subjective and it is possible that implants assessed as intact or partially intact were not functional. ...
... Initially done to improve histopathological evaluation of avian skin that Use of translucent self-adhesive tape attached to skin biopsy sites before obtaining skin biopsies by using a standard skin biopsy punch instrument to prevent rolling and contraction of skin biopsy specimens during collection and fixation. (46) ...
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