Sandra F Simmons’s research while affiliated with Vanderbilt University and other places

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Publications (176)


Mentored Quality Improvement Strategies to Enhance Deprescribing During COVID-19: A Case Series of Three Nursing Homes
  • Article

June 2025

The Senior Care Pharmacist

Kristina M. Niehoff

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April Hanlotxomphou

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Mattie Brady

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[...]

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Sunil Kripalani

Background In post-acute and long-term care (PALTC) facilities, challenges exist to optimizing medication management. During the COVID-19 pandemic, nursing homes (NHs) sought ways to streamline medication administration and deprescribe medications. Objective This quality improvement (QI) initiative aimed to implement medication-related projects in three NHs. Methods Each NH was assigned a nurse practitioner (NP) QI mentor who led the facilities through the QI efforts using validated tools during the COVID-19 pandemic. Each facility selected their medication-related topic of interest. The QI efforts were implemented by the NH staff including the director of nursing, providers, and consultant pharmacists. Results Two facilities focused on general medication deprescribing, and the third facility focused specifically on antipsychotic deprescribing. Successful deprescribing interventions occurred in all three facilities; however, they did not achieve all QI goals. Conclusion Successful deprescribing can occur using mentored implementation of QI tools. However, it is imperative to have key stakeholders within NHs who are supportive and engaged in the deprescribing process, such as facility staff (leadership and front-line staff), facility providers, consultant pharmacists, and residents/families.


An Objective Method to Determine Nurse Staffing for an Acute Care for Elders ( ACE ) Hospital Unit: Discrete Event Simulation

May 2025

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2 Reads

Journal of the American Geriatrics Society

Background Many hospitals have acute care for elders (ACE) units or engage in programs to enhance care for older inpatients. However, few studies have objectively evaluated nurse staffing models to support care for older inpatients. Methods This study applied discrete event simulation (DES) to an ACE unit to objectively evaluate registered nurse (RN) and nursing assistant (NA) staffing allocations. Research staff collected standardized, objective data related to nursing tasks and time requirements to model the ACE unit clinical care environment and evaluate varying RN and NA staffing allocations on measures of nursing workload, care quality, and care efficiency. Results On a 22‐bed ACE unit, 85% of patients were aged 65 or older, 37% had cognitive impairment, and 89% required toileting and/or mobility assistance. Nurse care routines were interrupted frequently by unscheduled patient care requests, with an average frequency of 6.1 (±1.6) requests per hour. DES was used to simulate four different RN and NA staffing allocations. Results showed the most common staffing (four RNs and one NA) resulted in the highest nursing workload rates (89% and 88% for RNs and NAs, respectively) and the highest rate of predicted care omissions (6.2%). Additionally, RNs were predicted to help with 83% of NA care tasks related to toileting and mobility assistance. Alternative allocations of four RNs and three NAs or five RNs and two NAs resulted in more feasible workload rates, lower rates of care omissions, and less reliance on RNs for NA care tasks. Conclusions DES provides an objective method to identify nurse staffing needs for an ACE hospital unit. This approach can be used to safely evaluate the potential impact of varying nurse staffing allocations. The DES model for the ACE unit is adaptable to other types of hospital units that care for older patients.


FEASIBILITY AND ACCEPTABILITY OF IMPLEMENTING DEPRESCRIBING IN POST-ACUTE HOME HEALTH CARE

December 2024

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10 Reads

Innovation in Aging

Polypharmacy is common in home health care (HHC), but no deprescribing intervention has been tested in HHC. In a prior study, we identified essential components of deprescribing by interviewing patients, primary, acute and post-acute care providers, pharmacists, and HHC nurses in 12 U.S. states. This study assessed the feasibility and acceptability of deprescribing in HHC through the collaboration of an HHC nurse and a pharmacist to conduct home medication review, deprescribing assessment, primary care provider discussion, patient education, deprescribing implementation, and safety monitoring. In 11 patients who received HHC following hospital discharge, we assessed feasibility and acceptability of deprescribing through surveys and qualitative interviews with patients, providers, and study interventionists. Patients received deprescribing components over 3-4 home visits. On average, the HHC nurse spent 1 hour/home visit/patient, the pharmacist spent 1 hour on deprescribing assessment/patient, and the provider spent 5 minutes / patient to review and implement deprescribing recommendations. Over 70% of deprescribing recommendations were accepted by providers, with 30% not accepted mostly due to patient preference. Providers found deprescribing “very feasible,” but noted barriers such as time constraints and patient preferences. The HHC nurse found deprescribing components “very feasible,” citing the multidisciplinary approach as a facilitator but noting communication challenges with providers. Providers and patients both generally reported that deprescribing components were helpful and led to patients feeling empowered. In conclusion, deprescribing components were feasible in HHC and highly acceptable to patients and providers. Effective communication between patients, HHC nurses, and providers is crucial for deprescribing in HHC.





Figure. Specialty-Level Variation in the Proportion of Physicians Participating in the Veterans Health Administration's Community Care Network, 2019
Physicians and Specialties in the Veterans Health Administration’s Community Care Network
  • Article
  • Full-text available

May 2024

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11 Reads

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2 Citations

JAMA Network Open

This cross-sectional study of data from the US Veterans Health Administration examines the availability of services provided through community care networks by specialty and clinical characteristics.

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Emergency department visits and hospital readmissions after a deprescribing intervention among hospitalized older adults

May 2024

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23 Reads

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3 Citations

Journal of the American Geriatrics Society

Background Deprescribing is the planned/supervised method of dose reduction or cessation of medications that might be harmful, or no longer be beneficial. Though benefits of deprescribing are debatable in improving clinical outcomes, it has been associated with decreased number of potentially inappropriate medications, which may potentially reduce the risk of adverse events among hospitalized older adults. With unclear evidence for deprescribing in this population, this study aimed to examine time‐to‐first unplanned healthcare utilization, which included 90‐day emergency department (ED) visits or hospital readmission and associated predictors, during a deprescribing intervention. Methods A secondary data analysis of a clinical trial (Shed‐MEDS NCT02979353) was performed. Cox regression was used to compare the time‐to‐first 90‐day ED visit/readmission/death from hospital discharge for the intervention and control groups. Additionally, we performed exploratory analysis of predictors (comorbidities, functional health status, drug burden index (DBI), hospital length of stay, health literacy, food insecurity, and financial burden) associated with the time‐to‐first 90‐day ED visit/readmission/death. Results The hazard of first 90‐day ED visits/readmissions/death was 15% lower in the intervention versus the control group (95% CI: 0.61–1.19, p = 0.352, respectively); however, this difference was not statistically significant. For every additional number of comorbidities (Hazard ratio (HR): 1.12, 95% CI: 1.04–1.21) and each additional day of hospital length of stay (HR: 1.04, 95% CI: 1.01–1.07) were significantly associated with a higher hazard of 90‐day ED visit/readmission/death in the intervention group; whereas for each unit of increase in pre‐hospital DBI score (HR: 1.08 and HR 1.16, respectively) was significantly associated with a higher hazard of 90‐day ED visit/readmission/death in the control group. Conclusions The intervention and control groups had comparable time‐to‐first 90‐day ED visit/readmission/death during a deprescribing intervention. This finding suggests that deprescribing did not result in a higher risk of ED visit/readmission/death during the 90‐day period following hospital discharge.




Citations (79)


... Numerous studies have demonstrated its effectiveness in improving access to care [4][5][6], ensuring continuity [7,8] and quality of care [9,10], increasing patient satisfaction [11][12][13][14][15], and reducing costs [16][17][18] and wait times [2,[19][20][21][22]. Moreover, internet-based clinical support initiatives between novice and expert professionals are being implemented in both urban [23][24][25] and rural [26,27] settings specifically to address challenges related to the shortage of qualified health care workers. ...

Reference:

Barriers to and Facilitators of Implementing Overnight Nursing Teleconsultation in Small, Rural Long-Term Care Facilities: Qualitative Interview Study
Strategies to Evaluate New Models of Nursing Care to Meet Hospital Staffing and Patient Care Needs
  • Citing Article
  • June 2024

Nurse Leader

... This program is known as "community care" (CC) [28,29]. The CC network is broad and includes nearly a half million physicians nationwide, including 57.6% of all physicians that participate in Medicare [30]. ...

Physicians and Specialties in the Veterans Health Administration’s Community Care Network

JAMA Network Open

... Multidisciplinary approaches, including physicians, nurses, and computerized decision-support systems, also worked well to aid deprescribing success [8,13,14].This study also reinforces that there is strong evidence that deprescribing interventions reduces the medication burden. Some studies show a decrease in emergency department visits following deprescribing [15], while others report no significant change in hospitalization rates [16,17]. These discrepancies may be due to variations in study populations, medications, and intervention durations. ...

Emergency department visits and hospital readmissions after a deprescribing intervention among hospitalized older adults
  • Citing Article
  • May 2024

Journal of the American Geriatrics Society

... Unclear and uncoordinated roles among disciplines complicated effective interdisciplinary practice essential for deprescribing. 46 Individuals such as physicians, nurses, pharmacists and older people prioritized different factors in deprescribing. 44 For instance, a small proportion of nurses (13.8%) and physicians (12.2%) were willing to discontinue antipsychotics with shared willingness in only 4.2% of cases, indicating differing evaluations of the same person by nurses and physicians. ...

Challenges in Deprescribing Among Older Adults in Post-Acute Care Transitions to Home
  • Citing Article
  • October 2023

Journal of the American Medical Directors Association

... These findings align with studies suggesting that insufficient deprescribing training contributes to physician reluctance [35]. Unlike long-term care settings, where deprescribing is integrated into routine practice, hospital environments often prioritise immediate treatment needs, limiting deprescribing opportunities [36]. Moreover, Beliefs about Consequences influenced physicians' engagement with deprescribing. ...

How to Deprescribe Potentially Inappropriate Medications During the Hospital-to-Home Transition: Stakeholder Perspectives on Essential Tasks
  • Citing Article
  • August 2023

Clinical Therapeutics

... A recent study looking at the barriers and facilitators to deprescribing before surgery from patient and primary care providers' perspectives suggested similar barriers to those identified in the primary care setting and in medical inpatients. 10 There is limited research exploring the perspectives of healthcare professionals, patients and carers on medication review and deprescribing in inpatient surgical settings. ...

Barriers and facilitators to deprescribing before surgery: A qualitative study of providers and older adults
  • Citing Article
  • August 2023

Geriatric Nursing

... The study did not investigate reasons for non-participation of patients or their next-of-kin. Existing studies indicate the factors contributing to non-participation can vary, encompassing insufficient information, lack of recognition of personal resource limitations or healthrelated concerns [48]. Understanding these factors would add to a comprehensive analysis of PPI in this specific setting of nursing homes. ...

Why do older adults decline participation in research? Results from two deprescribing clinical trials

Trials

... 26 -Patient care: improved referrals to community services for patients post-fall, 26 better function at follow-up, 25 better quality of life at follow-up, 25,26 and reduction in delirium duration for admitted patients. 29 Details of the publications are summarized in Table 1. ...

Effect of physical and occupational therapy on delirium duration in older emergency department patients who are hospitalized

Journal of the American College of Emergency Physicians Open

... One of the RCTs spanning over 4 years in a hospital setting showed 142 intervention group participants consuming a mean of 14% fewer medications. In addition, the intervention decreased patients' exposure to possibly undesirable medications and the Drug Burden Index (Vasilevskis et al., 2023). One of the meta-analyses showed a 41% decrease in mortality rate with deprescription in hospitalized patients at the end of their lives (Veronese et al., 2024). ...

Deprescribing Medications Among Older Adults From End of Hospitalization Through Postacute Care: A Shed-MEDS Randomized Clinical Trial
  • Citing Article
  • February 2023

JAMA Internal Medicine

... Furthermore, patients who participated in mobility programs preserved function and were more likely to discharge home rather than to a subacute setting (Babine et al., 2013). Rose et al. (2020) reported that 47% of falls documented over a 12-month period were related to toileting, and 80% of hospitalized adult patients had no mobility assessment completed to determine level of assistance (Tzeng, 2010;Wilson et al., 2022). A toileting-related fall is a fall that occurs from the time a patient responds to the need to void and begins to move to address that need to returning to the intended surface (e.g., bed, chair) (Rose et al., 2020). ...

TOILETING AND MOBILITY ASSISTANCE PREFERENCES OF PATIENTS ON AN ACUTE CARE FOR ELDERS (ACE) UNIT

Innovation in Aging