Samantha Moe's research while affiliated with College of Family Physicians of Canada and other places

Publications (28)

Article
Objective: To summarize 10 high-quality studies or guidelines from 2021 that have strong relevance to physicians in comprehensive family practice. Selecting the evidence: Routine literature surveillance of abstracts in high-impact journals and EvidenceAlerts was completed by the PEER (Patients, Experience, Evidence, Research) team, a group of he...
Article
Objectif: Résumer 10 études ou lignes directrices de grande qualité publiées en 2021 qui présentent un intérêt marqué pour les médecins qui ont une pratique familiale complète. SÉLECTION DES DONNÉES PROBANTES: L’équipe PEER (Patients, Experience, Evidence, Research), un groupe de professionnels de la santé dont la recherche s’intéresse à la médecin...
Article
Objective: To develop a clinical practice guideline to support the management of chronic pain, including low back, osteoarthritic, and neuropathic pain in primary care. Methods: The guideline was developed with an emphasis on best available evidence and shared decision-making principles. Ten health professionals (4 generalist family physicians,...
Article
Objective: To determine the proportion of patients with neuropathic pain who achieve a clinically meaningful improvement in their pain with the use of different pharmacologic and nonpharmacologic treatments. Data sources: MEDLINE, EMBASE, the Cochrane Library, and a gray literature search. Study selection: Randomized controlled trials that rep...
Article
Objective: To summarize high-quality studies for 10 topics from 2020 that have strong relevance to primary care practice. Selecting the evidence: Study selection involved routine literature surveillance by a group of primary health care professionals. This included screening abstracts of high-impact journals and EvidenceAlerts, as well as search...
Article
Objectif: Faire la synthèse d’études de grande qualité sur 10 sujets, publiées en 2020, qui sont d’une grande pertinence pour la pratique des soins primaires. SÉLECTION DES DONNÉES PROBANTES: La sélection des études s’est faite à la suite d’une surveillance systématique de la littérature scientifique par un groupe de professionnels de la santé en s...
Article
Objective: To determine the proportion of chronic low back pain patients who achieve a clinically meaningful response from different pharmacologic and nonpharmacologic treatments. Data sources: MEDLINE, EMBASE, Cochrane Library, and gray literature search. Study selection: Published randomized controlled trials (RCTs) that reported a responder...
Article
Full-text available
Objective: To determine the effect of mask use on viral respiratory infection risk. Data sources: MEDLINE and the Cochrane Library. Study selection: Randomized controlled trials (RCTs) included in at least 1 published systematic review comparing the use of masks with a control group, either in community or health care settings, on the risk of...
Article
Objective: To determine how many patients with chronic osteoarthritis pain respond to various non-surgical treatments. Data sources: PubMed and the Cochrane Library. Study selection: Published systematic reviews of randomized controlled trials (RCTs) that included meta-analysis of responder outcomes for at least 1 of the following intervention...
Article
Full-text available
Objective: To summarize high-quality studies for 10 topics from 2018 that have strong relevance to primary care practice. Quality of evidence: Study selection involved routine literature surveillance by a group of primary care health professionals. This included screening abstracts of important journals and Evidence Alerts, as well as searching...
Article
Full-text available
Objectif: Résumer des études de qualité supérieure sur 10 sujets en 2018 qui sont étroitement en rapport avec la pratique des soins primaires. QUALITÉ DES DONNÉES: Pour choisir les études, un groupe de professionnels des soins de santé primaires a exercé une surveillance systématique des publications scientifiques, notamment par un examen des résum...

Citations

... A useful metric of this phenomenon is the number needed to treat, which defines how many patients need to be given a particular treatment to see a clinically meaningful reduction in pain. Ideally, this should be 1, but usually it ranges from 5 to 20 for chronic pain conditions (98,99). Apart from low efficacy across the pain spectrum, most available analgesics also have a low persistence of activity when used chronically, including both opioids and NSAIDs (100,101). ...
... Analgesics, non-steroidal anti-inflammatory drugs (NSAIDs) and, to a lesser degree, muscle relaxants are effective remedies for acute nonspecific low back pain. The effectiveness of NSAIDs for acute low back pain was recently revised: NSAIDs are slightly more effective than placebos for short-term pain reduction (moderate certainty), disability (high certainty), and global improvement (low certainty); however, the magnitude of these effects is minor and not clinically relevant [58]. A systematic review published in 2017 on the effects of spinal manipulation reported modest improvements in pain and function with transient minor musculoskeletal harms. ...
... As it was resistant to conventional therapy, I had to search for new ways to diagnose and treat it, and I am not alone. In the absence of an accurate diagnosis, a multitude of treatments have been proposed, as outlined by Kirkwood et al., all of which (and others he did not list) I tried and sent my patients to with marginal success [18]. ...
... They are also applicable in adjunctive therapy in the treatment of hypercalcemia, acute mountain sickness, cataracts, and prime hyperaldosterism. 16−19 Several categories of diuretics are well-known, such as thiazides, carbonic anhydrases, etc. 20 Long-term treatment with this class of drugs has recently been correlated with the photoinduced formation of carcinomas, 21 and some have been documented to have a phototoxic impact as a side effect. 22 Pharmacological reports of toxic effects linked to the application of clopamide have sparked interest in the drug's photoreactivity. ...
... You endorsed as valid, an "investigation" that was known by you to be a fraud, a vaccine promotional stunt, that was so corrupt that it had to be retracted within a few days of global publication. 16 But let us focus on Beta-coronavirus, specifically its history versus SARS-CoV-2 . . . as you are aware, the former SARS outbreak dates to 2003. ...
... 31 There is limited evidence that the use of masks might reduce the risk of viral respiratory infections. 32 According to MacIntyre et al, 33 there was a higher risk of coronavirus infection in health care workers who wore a mask compared to a respirator. No evidence exists to claim the face masks during exercise offer additional protection from the droplet transfer of the virus. ...
... 12 There are several decision aids developed for clinicians to help them to discuss non-operative treatment options with their patients having OA-related pain. Lindblad et al. 16 reported that the decision aids should be combined with similar systematic reviews and tools on other types of pain to inform future guideline development. Currently, clinicians are encouraged to practice evidence-based medicine, as well as patient-centered medicine. ...
... Several randomised controlled studies have shown a symptomatic effect superior to placebo (Noack et al., 1994) and not inferior to that of an NSAID (Müller-Fassbender et al., 1994). The most recent meta-analyses confirm the symptomatic efficacy of pharmaceutical grade glucosamine sulphate, with results showing a standardised mean difference ranging from −0.29 [95% CI −0.49 to −0.09] (Sellam et al., 2020) and −0.35 [−0.54 to −0.16] (Knapik et al., 2018;Beaudart et al., 2020;Ton et al., 2020), which evidences a moderate effect not significantly different from results obtained with other classes of oral symptomatic OA drugs, notably the NSAIDs. OARSI classifies the efficacy of glucosamine as "uncertain," due to a very variable effect size ranging from 0.17 [0.05-0.28] ...
... It should be noted that in addition to being supported only by low certainty of evidence and having numerous adverse events, with NNHs below NNTs, there was obvious heterogeneity in the types and doses of opioids used in the included trials. This, along with the potential risk of developing opioid use disorder with longer-term use, 22 makes clinical application challenging. ...
... Une posologie moins fréquente améliore la tolérabilité 1,3,5 , mais la durée de la thérapie pourrait être plus longue qu'avec une dose QD, en raison des augmentations plus faibles de l'HB. Il a été avancé que le gluconate ou le sulfate ferreux favorisait l'adhésion 8,9 . Une thérapie de consolidation pendant 3 mois est recommandée après la correction de la carence en fer pour reconstituer les réserves 10 . ...