Saman Ghalamkari's research while affiliated with Islamic Azad University-Arsanjan branch and other places

Publication (1)

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Macrophages are key immune cells that respond to infections, and modulate pathophysiological conditions such as wound healing. By possessing phagocytic activities and through the secretion of cytokines and growth factors, macrophages are pivotal orchestrators of inflammation, fibrosis, and wound repair. Macrophages orchestrate the process of wound...


... In the present study, infiltration of these cells was associated with high-risk scores with poor prognosis, confirming the contribution of these cells in the breast cancer progression (Chen et al. 2017;Farmaki et al. 2020;Mouchemore et al. 2018). The polarization of macrophages to the M1 or M2 phenotype often results in different cytokine secretion and function (Hassanshahi et al. 2022;Lee 2019). M1 macrophages usually produce IL-12 and tumor necrosis factor with anti-tumor effects, while M2 macrophages often produce inhibitory cytokines such as IL-10, which have the opposite effects (Jeong et al. 2019). ...