Sabrina Gentzsch’s scientific contributions

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Publications (1)

Fig. 1. The patient presented with multiple basal cell carcinomas on the head, a typical feature for Gorlin syndrome.  
Fig. 2. (a) Dual­energy X­ray­absorptiometry (DEXA) of the left hip. (b) T­score of –2.6 (black square) for the neck of the femoral bone (bone mineral density: BMD). (c) Results of DEXA showing BMD, T­score, Z­score and percentage compared to indicated reference population (young adults, age match) at different regions of the left hip and mean values.  
Iatrogenic Vitamin D Deficiency in a Patient with Gorlin Syndrome: The Conundrum of Photoprotection
  • Article
  • Full-text available

November 2013

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112 Reads

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4 Citations

Acta Dermato-Venereologica

Sabrina Gentzsch

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Johannes Steffen Kern

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Stefan Loeckermann

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Acute and chronic UV exposure is an important risk factor leading to photocarcinogenesis, photoimmuno-suppression and photoaging (1, 2). Patients with Gorlin syndrome (GS) harbour a hereditary predisposition to develop basal cell carcinomas (BCC) and are, therefore, advised that effective sun protection is essential and can help reduce skin cancer risk (1-4). On the other hand, adherence to strict sun-protection habits can result in vitamin D deficiency, which has been demonstrated in many patients with GS (2, 3). Vitamin D deficiency is associated with an increased risk of osteomalacia, bone fractures, autoimmune diseases, cancer and cardiovascular disease (1).

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