Sa’ar Lanir-Azaria's research while affiliated with Hebrew University of Jerusalem and other places

Publication (1)

Article
The induction of general anesthesia shares many features with the transition from wakefulness to non-rapid eye movement (NREM) sleep, suggesting that the two types of brain-state transition are orchestrated by a common neuronal mechanism. Previous studies revealed a brainstem locus, the mesopontine tegmental anesthesia area (MPTA), that is of singu...

Citations

... The main outcomes of the present study were: (1) development of experimental protocols that permitted the application of the bonus time approach in mice, and (2) exploitation of these protocols in the tentative location of the MPTA in the mouse. However, it still needs to be shown that other properties of the MPTA in rats are replicated in mice, such as electrographic paradoxical anesthesia and the effect of MPTA lesions on anesthetic potency, sleep-wake cycling and syncope in response to hypercapnia (Meiri et al. 2016;Lanir-Azaria et al. 2018;Minert et al. 2020;Avigdor et al. 2021). ...