S.C. Bhattacharyya’s research while affiliated with Indian Institute of Technology Bombay and other places

... Daucosterol and beta-sitosterol have been extracted from the roots of plant. The other constituents that are present in I. racemosa are dihydroalantolactone, dihydro isoalantolactone, inunolide, dihydroinunolide, isoalloalantolactone (Ravindranath et al. 1978), alloalantolactone (Bhandari and Rastogi 1983), inunal, isoinunal (Kalsi et al. 1988(Kalsi et al. , 1989, alantodiene, etc. It is also a source of essential oil. ...

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Effect of Natural Products on Improvement of Blood Pathophysiology for Management of Sickle Cell Anemia

... Furthermore, good stereoselectivity was obtained in the case of prezizaenes, -selinene, and R-gurjunene (Nagashima and Yoshida, 1981; Richardson et al., 1991; Palmade et al., 1963). Bourbon vetiver essential oil (BVEO), considered as the best vetiver essential oil in the world for its exceptional olfactory qualities, is used in many perfumes known as " top quality goods " (Ganguly et al., 1978; Garnero, 1971). From a chemical point of view, this oil is extremely complex and particularly rich in sesquiterpenes . ...

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Sesquiterpenic Epoxides and Alcohols Derived from Hydrocarbons of Vetiver Essential Oil

... [352,353] The (À)enantiomer of 138 was later isolated from several other plants. [177,349,[354][355][356][357][358][359][360][361][362][363][364][365][366][367] Full 1 H-and 13 C-NMRd ata in CDCl 3 and C 6 D 6 have been reported. [367,368] ...

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Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis

... Since the first discovery of β-bergamotene in 1963, about 33 bergamotane type sesquiterpenoids have been isolated, which were classified into five core ring systems, bicyclo[3.1.1]heptan [15][16][17][18][19][20][21][22][23], tricyclo [4.3.0.0 4,7 ]nonane [12,20,[24][25][26][27], tricyclo[3.3.1.0 2,7 ]nonane [12,24], 6/4/5/5 tetracyclic skeleton [20,23,[28][29][30], and 5/6/4/5 tetracyclic skeleton [23] (Figure S2). ...

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Brasilterpenes A–E, Bergamotane Sesquiterpenoid Derivatives with Hypoglycemic Activity from the Deep Sea-Derived Fungus Paraconiothyrium brasiliense HDN15-135

... The earliest literature on agarwood was dated in 1959, which reported on the extraction of sesquiterpene alcohol from the agarwood oil (Jain and Bhattacharyya, 1959), but our sampling scope is insufficient to encompass the entire research history. However, there were only a few systematic studies published over the decades, indicating a low level of academic interest in agarwood during that period. ...

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A BIBLIOMETRIC ANALYSIS OF AGARWOOD RESEARCH AND THE IMPACT OF CITES LISTING

... The chirality of the γ-lactone moiety is known to affect their aroma-inducing properties (Hwang et al., 2000;Mosandl and Günther 1989). Interestingly, the carbon atom at position 4 in parthenolide is found in the R-form (Bawdekar et al., 1966). We have confirmed that this also applies to costunolide and santonin (Figure 1) which are active against cocaine using molecular modeling software as described. ...

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Minimal structural requirements of alkyl γ-lactones capable of antagonizing the cocaine-induced motility decrease in planarians

... Apart from this, the claimed therapeutic uses also need to be clinically substantiated. , calarenol, and nardostachone Sastry et al. 1966, Pai et al. 1971, Rucker et al. 19786 Spriyajatamol, jatamol-A,jatamol-B Bagchi et al. 1988Bagchi et al. , 1990Bagchi et al. , 19917 Nardoperoxide, isonardoperoxide, and nardoxide Takaya et al. 1998 ...

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Review of Nardostachys grandiflora: An Important Endangered Medicinal and Aromatic Plant of Western Himalaya

... Khusinol (1) and its chemically modified products (2)(3)(4)(5)(6)(7)(8) were found to be more effective against D. oryzae, followed by F. moniliforme and A. triticina, in inhibiting fungal growth. The results demonstrated a potential relationship between chemical structure and in vitro antifungal activity of the compounds tested. ...

Reference:

Synthesis and Antifungal Activity of Khusinol and its Derivatives

... The organic layer was washed with water until neutral, dried over MgSO 4 and concentrated. Flash chromatography (cyclohexane/ethyl acetate gradient from 99:1 to 90:10) followed by bulb-to-bulb distillation gave 7.88 g of pure compound 33 (58%). 1 (±)-2-(Cyclohexylcarbonyl)cyclohexanone (38) Obtained in 43% yield according to the general procedure above. (±)-2-(3-Cyclopentylpropanoyl) cyclopentanone (40) Same general procedure as above, but starting from 1-Nmorpholinocyclopentene (Sigma Aldrich C114901). ...

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The quest for odorants having salicylate notes

... Thirty-two phytochemicals (1-32) were isolated from the hemp roots extract, and their chemical structures ( Fig. 1) were elucidated on the basis of spectroscopic analysis (by NMR and MS) and comparisons of the literature reported values as follows: cannabinol (1) (Wang et al., 2017); (9R,10 S)-6, 6,9-trimethyl-3-pentyl-7,8,9,10-tetrahydro-6 H-benzo[c]chromene-1,9,10-triol (2) ; (-)-7R-cannabicoumarononic acid A (3) (Radwan et al., 2009); (9R,10 S)-6, 6,9-trimethyl-3-propyl-7,8,9,10-tetrahydro-6 H-benzo[c]chromene-1,9,10-triol (4) ; cannabivarin (5) (Wang et al., 2017); cannabidiol (6) (Marchetti et al. 2019); 4-hydroxy-3-methoxybenzaldehyde (7) (Ito et al., 2001); 4-hydroxybenzaldehyde (8) (Bouaicha et al., 1994); 4-hydroxy-3,5-dimethoxybenzaldehyde (9) (Xue et al., 2013); syringic acid (10) (Queirós et al., 2020); vanillic acid (11) (Xu et al. 2022); 2,6-dimethoxyphenol (12) (Goda et al., 1987); (2E)-3-(4-hydroxyphenyl)-2-propenoic acid (13) (Seal, 2013) (Bennett et al., 1990); 1 H-indole-3-carboxaldehyde (16) (Wang et al., 2012); 3-(4-hydroxyphenyl)-2-propenoic acid ethyl ester (17) (Pizzolatti et al., 2006); 4-hydroxyphenethyl trans-ferulate (18) (Fujita et al., 1995); 1,2-diguaiacyl-1-ethoxy-3-propanol (19) (Mohammed et al., 2022); (+)-4-ketopinoresinol (20) (Chen et al., 2012); dadahol A (21) (Devanathan and Stalin 2020); (+)-oleanolic acid (22) (He et al., 2021), epipseudotaraxastanediol (23) (Hinge et al., 1966); 3-epifriedelinol (24) (Sousa et al., 2012); 9,12-octadecadienoic acid (9Z, 12Z) -friedelin (25) (Zhou & Guo, 2009); β-sitosterol (26) (Kadowaki et al., 2003); 5α,8α-epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol (27) (Gao et al., 2007); stigmast-4-en-3-one (28) (Smania et al., 2003); 9, 12-octadecadienoic acid (9Z, 12Z) -methyl ester (29) (Huh et al., 2010); α-linolenic acid (30) (Kishino et al., 2003); linoleic acid (31) (Yoon et al., 2015); and dotriacont-1-ene (32) (Chen et al., 2010). The isolated phytochemicals can be divided into two classes, the cannabinoid-type (1-6) and the non-cannabinoid-type (7-32). ...

Reference:

Chemical constituents of industrial hemp roots and their anti-inflammatory activities