S Wessler’s research while affiliated with Washington University in St. Louis and other places

... 47,48 However, it was only in the 1960s, with the establishment of the ICU and prolonged mechanical ventilation, as well as hyperbaric O 2 therapy, that serious concern over clinical O 2 toxicity arose in response to numerous case reports in both adults and neonates. 16,23,[49][50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67] The first clinical report of apparent HALI in adults was published in 1958. 47 Other reports soon appeared associating O 2 therapy with pulmonary hyaline membrane formation in adults who died of progressive respiratory failure. ...

Reference:

Hyperoxic Acute Lung Injury

... These changes were bound to happen and if the department wants to thrive as an organization, they should be able to anticipate, plan and prepare for such changes. [10][11][12] Based on the results of the training needs assessment done among CHD 4A staff in 2015, it was found that managing change was one of the competencies that had the widest gap. Hence, an intervention to respond to this need was imperative. ...

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Implementation of the Training Program on Retooling of Personnel of the Center for Health Development Calabarzon, Philippines

... The two most widely used orthotopic diversions were described by Studer and Hautmann. Studies focused on ileal neobladders show they have a volume capacity comparable to colon neobladders; pressure with maximum capacity is smaller in ileum neobladders, resulting in better urinary continence. 1 Paananen et al. compared clinical, enterocystometric and urofluxometric characteristics of orthotopic urinary diversions carried out in patients with bladder cancer including 78 male patients; 66 had ileal neobladder (30 Studer, 24 Hautmann and 12 T-shaped bag) and 12 patients had right colon urinary reservoirs. They found no significant differences in enterocystometry evaluation between ileal and colon urinary diversions as for volume and base pressures, except for magnitude of contractions, which were higher in colon reservoirs than ileal. ...

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Management of bladder cancer with Studer orthotopic neobladder: 13-year experience

... Tracheobroncholitis develops after a latent period of 4-22 h when breathing oxygen with a PO 2 of 95 kPa (713 mmHg), but may occur as early as 3 h while breathing oxygen at 300 kPa (2250 mmHg) [21,24]. After 24 h, the capillary endothelium and alveolar type 1 cells disrupt, as a result of which the pulmonary interstitium becomes oedematous and fibrin membranes may form along the alveolar lining [25]. Depending on the PO 2 , the exudative phase can be found up to 5.5 days of continued oxygen breathing. ...

Reference:

Oxygen, the lung and the diver: Friends and foes?

... Vasodegeneration and impaired endothelial repair is central to many ischaemic retinopathies including diabetic retinopathy As outlined above, diabetic retinopathy is the most common ischaemic disorder of the retina and remains the leading cause of registrable blindness in the working population of many industrialised countries (Roodhooft, 2002). Although there is some phenotypic variation between Type 1 and Type 2 diabetes, for both patient groups after more than 10 years disease duration the prevalence of diabetic retinopathy is around w75% and increases to w95% by 20 years (Fong et al., 2004). Although there is hope that effective pharmacological interventions may reach the market within the next 5 years, at present there are few preventative measures available to patients beyond maintenance of tight glycaemic control (DCCT, 1993), cessation of smoking (Schram et al., 2003), blood pressure control (Kohner et al., 1995) and correction of dyslipidaemia (Chowdhury et al., 2002) which significantly protect against diabetic retinopathy progression. ...

Reference:

Prog Ret Eye Res EPC REVIEW

... Сочетание химиотерапии и андрогеновой/антиандрогеновой терапии В 1972 г. G.S. Gordan предположил, что при подборе андрогеновой терапии необходимо учитывать предшествующую терапию, так как при метастатическом РМЖ химиотерапия может оказывать неблагоприятное влияние на последующую гормонотерапию, направленную на АР [35]. I.S. Goldenberg et al., опровергая приведенную гипотезу, опубликовали данные исследования, в котором 18 пациенток получили химиотерапию до лечения калустероном (препарат группы андрогенов), из них 6 (35 %) продемонстрировали объективную регрессию опухоли в результате андрогеновой терапии [36]. ...

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DRUG THERAPY FOR ANDROGEN-POSITIVE BREAST CANCER

... Lazarus and Folkman (1984) presented two ways of coping. As early as 1969, the Kübler-Ross model was developed to describe a five-stage model of coping (Kübler-Ross 1969). Some 30 years later, 400 ways of coping were presented (Skinner et al. 2003). ...

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A Qualitative Study of Swedish Specialized Boarding Element Members’ Human Actions in Situations Perceived as New and/or Stressful after Participating in Long-Term Naval Hostile Deployment

... The use of FNAB has led to a reduction in the number of patients requiring surgery and increased the diagnostic yield of cancers at thyroidectomy. [24][25][26] ...

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Evaluation of solitary thyroid nodule by clinical presentation, fine needle aspiration cytology and thyroid scan

... COPD is a major problem in developing and developed countries alike. Estimates suggest that, in 2020, the condition will have become the world's third leading cause of death and the fifth cause of motor impairment or even disability, generating high social and economic costs [14]. Poland has a high number of COPD and asthma sufferers (estimated at approx. ...

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A Preliminary Attempt at the Identification and Financial Estimation of the Negative Health Effects of Urban and Industrial Air Pollution Based on the Agglomeration of Gdańsk

... A AU UT TH HO OR RS S: : H Jeroen Derijks, MSc, PharmD 1,2 , Luc JJ Derijks, PharmD, PhD 3 , Ingeborg Wilting, MSc, PharmD 2,4 , Professor Antoine CG Egberts, PharmD, PhD 2,4 A AB BS ST TR RA AC CT T In daily clinical practice there is a considerable variability in drug response between individuals. Pharmacogenetics is the science studying the interindividual variability in drug response resulting from genetic factors. ...

Reference:

Introduction to pharmacogenetics