April 1992
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30 Reads
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8 Citations
Hygiene and Sanitation
Sanitary and toxicological study of some guanidine containing polymers was done. Moderate toxicity of the polymers and absence of any specific effects were noted.
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... Reportedly, the mean lethal dose of Extrasept-1 in animal experiments is not much lower than that of purified ethanol: 9.7 vs. 12.3 mg/kg [31]. The median lethal dose (LD 50 ) of PHMG, administered orally, has been around 450 mg/kg for mice and 630 mg/kg for rats [32], while the animals died with signs of injury not of the liver but of the nervous system [33][34][35][36]. Lung lesions due to PHMG used in household humidifiers have been reported [37]. ...
- Citing Article
April 1992
Hygiene and Sanitation