Ryoji HAGIWARA's scientific contributions

Publications (7)

Article
However the osmotherapy in neurosurgical field have to control the intracranial been doing by intravenous in pressure and brain fusion of hypertonic a urea solution, this hypertonic urea solution has some undesirable side effect like rebound rising of pressure, local irritation, hemolysis, hematuria, some changes in ECG and great changes in electro...

Citations

... Contemporary studies have tried to define more precisely where and how this occurs. 6,7,[11][12][13][14][15] Using a systematic microinjection approach, we advanced the dedicated pathways idea with the discovery of a small nucleus, the mesopontine tegmental anesthesia area, which appears to be a key node in circuitry that enables anesthetic induction. [16][17][18] Briefly, we showed the following: (1) Delivering the γ-aminobutyric acid-mediated (GABAergic) anesthetics pentobarbital and propofol into the mesopontine tegmental anesthesia area, or the specific GABA A -receptor agonist muscimol, quickly and reversibly induces an anesthesia-like state closely resembling systemically induced general anesthesia (http://links. ...