Runsheng Wang's research while affiliated with Chinese PLA General Hospital (301 Hospital) and other places

Publications (14)

Article
Full-text available
Mitophagy, known as the main mechanism of mitochondrial quality control, determines the pathophysiology of septic cardiomyopathy, although the precise regulatory mechanisms remain elusive. Data from the present study suggested that receptor-interacting protein kinase 3 (RIPK3) expression could be enhanced in response to lipopolysaccharide (LPS) cha...
Article
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Background: The Coronavirus disease 2019 (COVID-19) pandemic has been a major threat to global health. Regional differences in epidemiological and clinical characteristics, treatment and outcomes of patients have not yet been investigated. This study was conducted to investigate these differences amongCOVID-19 patients in Hubei Province, China. Met...
Article
Full-text available
At present, it has been noticed that some patients recovered from COVID-19 present a recurrent positive RNA test of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) after being discharged from hospitals. The purpose of the current study was to characterize the clinical features of re-hospitalized patients with recurrent SARS-CoV-2 posit...
Article
Full-text available
Frontline healthcare nurses devoted themselves to deal with the outbreak of COVID-19, saving many lives. However, they are under incredible unknown psychological pressures with a considerable risk of infection. In this study, a self-administered questionnaire was used to survey 593 frontline nurses in Wuhan City and non-Hubei provinces for psycholo...
Article
The coronavirus disease 2019 (COVID-19) triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) erupted in Hubei Province of China in December 2019 and has become a pandemic. Severe COVID-19 patients who suffer from acute respiratory distress syndrome (ARDS) and multi-organ dysfunction have high mortality. Several studies have sho...
Preprint
Full-text available
Background Optimal fluid management in patients with COVID-19 has not been reported. This retrospective, multicenter study investigated the impact of intravenous infusion volume in the early stage of COVID-19 on clinical outcomes. Methods 127 patients from two tertiary hospitals were separated into the “conservative” and “liberal” groups based on...
Article
Full-text available
The COVID-19 pandemic is a significant global event in the history of infectious diseases. The SARS-CoV-2 appears to have originated from bats but is now easily transmissible among humans, primarily through droplet or direct contact. Clinical features of COVID-19 include high fever, cough, and fatigue which may progress to ARDS. Respiratory failure...
Article
Full-text available
Objective: Since the outbreak of Coronavirus Disease 2019 (COVID-19) in December 2019, various digestive symptoms have been frequently reported in patients infected with the virus. In this study, we aimed to further investigate the prevalence and outcomes of COVID-19 patients with digestive symptoms. Methods: In this descriptive, cross-sectional...
Article
Full-text available
Background: The global death toll from COVID-19 virus exceeds 21000. The risk factors for death were attributed to advanced age and co-morbidities, but haven't been accurately defined. Objectives: To report the clinical features of 85 fatal cases with COVID-19 in two hospitals in Wuhan. Method: Medical records of 85 fatal cases of COVID-19 bet...
Article
With over 1,800,000 cases and 110,000 deaths globally, COVID-19 is one of worst infectious disease outbreaks in history. The objective of this paper is to critically review the available evidence regarding the lessons learned from the Chinese experience regarding COVID-19 prevention and management. The steps that have led to a near disappearance of...
Article
The 2019-nCoV is officially called SARS-CoV-2 and is the cause of the disease named COVID-19. This viral epidemic in China has led to the deaths of over 1800 people, mostly elderly or those with an underlying chronic disease or immunosuppressed state. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003...

Citations

... The effect of COVID-19 as well as its limitation rules on the researched group has been investigated in a number of studies (McKune et al., 2021;Qin et al., 2021;Błaszczyk et al., 2022). Multivariable logistic regression models were used in many research to: (i) examine the possible risk factors defined as selfemotional problems (Ren H. et al., 2021) and (ii) compare the impact of COVID-19 assessments (Gomathi et al., 2021). ...
... On the other hand, one of the hallmarks of severe COVID-19 infection is cytokine release syndrome (CRS) [49]. It was determined in several studies that the levels of proinflammatory cytokines were higher in patients with COVID-19 compared to the healthy control subjects, while among the COVID-19 infected, they were significantly higher in the ICU-treated patients than in non-ICU-treated patients [50,51]. ...
... Only two studies performed genome sequencing from naso-/oropharyngeal samples, but full-length viral genomes could not be obtained [12,72]. Eight studies reported testing or follow-up of contacts, but no onward transmission was identified [70,[72][73][74][75][76][77][78]. The quality of observational studies was assessed on a scale of zero to 14. Included publications were rated between 3 [79] and 11 [65,78,80], as shown in S5 Table. ...
... In the most recent years, the emergence of the COVID-19 pandemic swept along a blast of vaccine candidates against SARS-CoV-2 [66,67]. Other related beta coronaviruses (CoV) such as SARS-CoV [68,69] and the Middle East respiratory syndrome-related coronavirus (MERS-CoV) [70] caused previous outbreaks in 2003 and 2012, respectively. Since then, diverse strategies have been undertaken in the prevention of SARS, particularly vaccines based on SAPNs [71]. ...
... From the first reviews on COVID-19, analyses have shown pneumonia as the most frequent medical manifestation. COVID-19-related pneumonia may be subsequently accompanied with ARDS, which is currently considered a hallmark of the immune-mediated clinical effect in SARS-CoV-2, and is consistent with the extremely acute respiratory syndrome (SARS-CoV) and MERS-CoV infections as two different varieties of acute respiratory infections resulting from Coronaviruses [32]. Moreover, ARDS can be described as a generalized and uncontrolled inflammatory response, which is potentially responsible for a wide range of morbidities and mortalities amongst the infected cases. ...
... All patients admitted to the COVID-19 Rehabilitation Unit of Istituti Clinici Scientifici Maugeri IRCCS (Gattico-Veruno, Piedmont, Italy) between March 2021 and May 2021 with a diagnosis of severe COVID-19 in the acute phase [32] were screened for inclusion. They still had a positive swab and were assessed in a temporary lab on day 25 of admission to the ward, as the maximum allowed length of stay in Piedmont (Italy) in the COVID-19 rehabilitation ward was 30 days. ...
... The Egyptian Journal of Internal Medicine (2022) 34:45 patients with gastrointestinal (GI) symptoms [4] that can occur with and without pulmonary manifestations of COVID-19 [5]. The reported prevalence of GI symptoms has been highly variable ranging from 3.8 to 61.3% [6][7][8][9][10][11][12]. ...
... Изучению развития нарушений сердечного ритма у пациентов, госпитализированных с COVID-19, посвящено много работ. Так, частота развития аритмий у госпитализированных пациентов варьировала от 8 до 17% и достигала 44-60% в отделениях интенсивной терапии [1][2][3][4][5]. В одном из крупных международных исследований с участием более 4500 пациентов частота появления аритмии составила 18%, при этом наиболее частыми их формами при COVID-19 были фибрилляция/трепетание предсердий [6]. ...
... A good COVID-19 prognosis is also linked to a high blood eosinophil count, common finding in allergic diseases in the context of a Th2 response [20]. Du Y et al., reported that eosinopenia was found in about 80% of patients died for COVID-19, considering it as a biomarker of worse prognosis and a predictor for the development of COVID-19 severity [22]. ...
... The current new coronavirus, officially named SARS-CoV-2, was first detected in Wuhan, China, in late December 2019.54 It was thought to have originated from wild animals at the Huanan market and then rapidly spread by person-to-person transmission, causing the pandemic disease named COVID-19, with various degrees of severity, from mild flu-like symptoms to pneumonia and death.54 ...