Ronald E Jung's research while affiliated with University of Zurich and other places

Publications (319)

Article
Aim To compare and report on the performance of implant‐supported fixed dental prostheses (iFDPs) fabricated using additive (AM) or subtractive (SM) manufacturing. Methods An electronic search was conducted (Medline, Embase, Cochrane Central, Epistemonikos, clinical trials registries) with a focused PICO question: In partially edentulous patients...
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Objectives The aims of Working Group 1 were to address the role (i) of the buccolingual bone dimensions after implant placement in healed alveolar ridge sites on the occurrence of biologic and aesthetic complications, and (ii) of soft tissue augmentation (STA) on the stability of clinical, radiographic, and patient‐related outcomes of implant treat...
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Objectives The aim of the ITI Consensus Workshop on zygomatic implants was to provide Consensus Statements and Clinical Recommendations for the use of zygomatic implants. Materials and methods Three systematic reviews and one narrative review were written to address focused questions on (1) the indications for the use of zygomatic implants; (2) th...
Article
Aim: The aim of the present study was (i) to evaluate the clinical performance of reduced-diameter implants placed in the molar area and (ii) to test whether monolithic zirconia implant-supported crowns lead to similar clinical outcomes compared to porcelain-fused-to-metal crowns. Materials and methods: A total of 76 patients needing a single im...
Article
Objectives: To evaluate the accuracy of implant placement using a dynamic navigation system in fully edentulous jaws and to analyze the influence of implant distribution on implant position accuracy. Materials and methods: Edentulous patients who received implant placement using a dynamic navigation system were included. Four to six mini screws...
Article
Objective: To compare efficiency and clinical efficacy of posterior single implant crowns (PSIC) fabricated using four digital workflows. Materials and methods: Twenty-two patients with one missing first molar were included. Each patient received four screw-retained implant crowns fabricated through four different workflows including a fully dig...
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The morphology and dimensions of the postextraction alveolar ridge are important for the surgical and restorative phases of implant treatment. Adequate new bone formation and preservation of alveolar ridge dimensions following extraction will facilitate installation of the implant in a restorative position, while preservation of soft tissue contour...
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Aim: To compare subepithelial connective tissue grafts (SCTG) versus guided bone regeneration (GBR) for the treatment of small peri-implant dehiscence defects in terms of profilometric (primary outcome), clinical, and patient-reported outcome measures (PROMs). Methods: Sixteen patients who presented with small buccal bone dehiscences (≤3 mm) fol...
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Abstract Purpose The purpose of this study was to perform a systematic review with meta-analysis on the long-term survival rates of zygomatic implants (ZI). ZI success, prostheses survival and success, sinus pathology and patient reported outcomes were also investigated. Methods Preferred Reporting Items for Systematic Review and Meta-Analyses (PRI...
Article
The aim of the study was to compare the clinical and radiographic outcomes of short dental implants (6-mm test group, TG) to longer implants (10-mm control group, CG) with single crown restorations after 10 y of loading. Patients requiring single-tooth replacement in the posterior jaws were randomly assigned to TG or CG. Implants were loaded with s...
Article
Objectives: To assess survival rates and compare technical, biological, and esthetic outcomes of customized zirconia and titanium abutments at 13 years post loading. Materials and methods: Initially, 22 patients with 40 implants in posterior regions were included. The sites were randomly assigned to 20 customized zirconia abutments with cemented...
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Purpose: The aim of this study was to compare changes in soft and hard tissue and the histologic composition following early implant placement in sites with alveolar ridge preservation or spontaneous healing (SH), as well as implant performance up to 1 year after crown insertion. Methods: Thirty-five patients with either intact buccal bone plate...
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Aim: Lack of consistently reported outcomes limits progress in evidence-based implant dentistry and quality of care. The objective of this initiative was to develop a core outcome set (COS) and measurements for implant dentistry clinical trials (ID-COSM). Materials and methods: This Core Outcome Measures in Effectiveness Trials (COMET)-registere...
Article
Aim: Lack of consistently reported outcomes limits progress in evidence-based implant dentistry and quality of care. The objective of this initiative was to develop a core outcome set (COS) and measurements for implant dentistry clinical trials (ID-COSM). Materials and methods: This Core Outcome Measures in Effectiveness Trials (COMET)-registere...
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Objectives: to evaluate the volumetric changes and peri-implant health at implant sites with and without previous soft tissue grafting over a 12-year observation period. Materials and methods: Eighteen patients received dental implants and simultaneous guided bone regeneration in the esthetic zone (15-25) for dental rehabilitation. Three months...
Article
Background: Peri-implant mucosa color (PMC) seems to be one of the main parameters affecting the esthetic outcome of implant therapy. However, more emphasis should be given to its assessment and reporting. Purpose: To describe the available evidence on methods to assess and report the color of the peri-implant mucosa (PMC) and the respective cli...
Article
Aim: To evaluate the fracture load and the type of failure of two different monolithic restorative materials bonded to standardized titanium bases and fabricated by two different procedures regarding the bonding-interface. Materials-methods: All screw-retained implant-crown specimens (n=40), subjected to fatigue by thermomechanical loading, diff...
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The purpose of this study was to compare the outcomes of a modified gingival graft technique, in which the released flap is positioned and sutured over the graft, with the conventional free gingival graft (FGG) procedure, when both are used for gingival augmentation. A 12-month, multicenter parallel randomized controlled trial was conducted. Subjec...
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Purpose Placement of dental implants has evolved to be an advantageous treatment option for rehabilitation of the fully or partially edentulous mandible. In case of extensive horizontal bone resorption, the bone volume needs to be augmented prior to or during implant placement in order to obtain dental rehabilitation and maximize implant survival a...
Article
Aim: The purpose of the present retrospective case series was to introduce a minimally invasive two-stage flapless crown lengthening procedure where a gingivectomy was avoided or minimized by reducing the bone height through a tunneling technique. Materials and method: Ten patients (median age 46.6 years, range 26.9 to 71.6 years) were included...
Article
Objective: To compare the peri-implant soft-tissue dimensional changes following guided bone regeneration between particulate (particle group) and collagenated soft-block-type (block group) biphasic calcium phosphate (BCP). Materials and methods: This study investigated 35 subjects: 18 particle-group and 17 block-group patients. Cone-beam comput...
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Background: Interventions to augment the mucosal thickness around dental implants are indicated to optimize esthetics and maintain peri-implant health. However, there is a lack of clinical data on the long-term performance of soft tissue substitutes, such as volume-stable collagen matrix (VCMX), compared to autogenous grafts, such as subepithelial...
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Objectives To analyze the influence of compression on tissue integration and degradation of soft tissue substitutes. Material and methods Six subcutaneous pouches in twenty-eight rats were prepared and boxes made of Al2O3 were implanted and used as carriers for soft tissue substitutes: a collagen matrix (MG), two volume-stable collagen matrices (F...
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Objectives: To analyze changes in radiographic bone density around short implants with and without cantilevers at 5 years post-loading. Materials and methods: Thirty-six patients with two adjacent posterior missing teeth participated in this randomized controlled clinical trial. All patients were randomly allocated to receive either two short im...
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Personalized Oral Healthcare has recently become the new trend word in medicine and dentistry. In this context, saliva diagnostics using various biomarkers seem to be the gateway to personalized dental diagnostics and therapy. But the terminology is not (yet) uniformly defined, furthermore it is unclear to what extent which salivary markers play a...
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The objective of this study was to clinically and radiologically evaluate the performance of a short (8 mm), 1-piece, zirconia implant after an observation period of 1 year in function. A total of 47 patients with 1 missing tooth in the position of a premolar or molar were recruited. Short (8 mm), 1-piece, zirconia implants were placed and loaded a...
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The aim of this study was to compare patient‐reported outcome measures (PROMs) of soft tissue substitutes versus autogenous grafts for soft tissue augmentation procedures at implant sites. Comprehensive and systematic literature searches were performed until December 2021. A focused question was formulated based on the Population, Intervention, Com...
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Background: Interventions to augment the mucosal thickness around dental implants are indicated to optimize aesthetics and maintain peri-implant health. However, there is a lack of clinical data on the long-term performance of soft tissue substitutes (VCMX) compared to autogenous grafts (SCTGs). The aim of the present randomized controlled trial wa...
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Objectives: To test whether or not the emergence profile (CONVEX or CONCAVE) of implant-supported crowns influences the mucosal margin stability up to 12 months post insertion of the final restoration. Materials and methods: Forty-seven patients with a single implant in the anterior region were randomly allocated to one of three groups:1) CONVEX...
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Aim To describe and compare the pontic site development for fixed-dental prostheses (FDPs) with and without soft tissue grafting up to one-year post insertion of FDPs. Materials and methods A convenience sample of 24 patients participating in an ongoing RCT was provided with three-unit tooth-borne FDPs. Six patients received a subepithelial connec...
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Objectives: In systematically healthy patients with an implant-supported fixed restoration (P), what is the influence of thin (E) as compared to thick (C) peri-implant soft tissues on aesthetic outcomes (O)? Methods: Following an a priori protocol, a literature search of six databases was conducted up to August 2020 to identify prospective/retro...
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Objectives: The aim of this study was to comprehensively assess the literature in terms of the effect of peri-implant mucosal thickness on esthetic outcomes and the efficacy of soft tissue augmentation procedures to increase the mucosal thickness with autogenous grafts or soft tissue substitutes. Material and methods: Two systematic reviews (SR)...
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Aim: To assess radiographic, restorative, clinical and technical outcomes as well as patient satisfaction of directly veneered zirconia restorations cemented on non-original titanium bases over 5 years. Material and methods: Twenty-four patients with a single missing tooth in the aesthetic zone were recruited. All patients received a two-piece i...
Article
Objectives To test the failure load and failure mode of a novel implant-crown interface specifically designed for the fabrication of fully personalized, abutment-free monolithic zirconia CAD-CAM crowns compared to conventional implant-abutment interfaces involving prefabricated or centrally manufactured abutments for zirconia CAD-CAM crowns. Metho...
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Objectives This study’s aim was to investigate the safety and performance of a self-assembling peptide matrix (SAPM) P 11 -4 for the treatment of periodontal disease in a controlled pre-clinical study. Materials and methods Acute buccal bony dehiscence defects (LxW: 5 × 3 mm) were surgically created on the distal root of four teeth on one mandible...
Article
Aim: To test whether soft-type block bone substitute used for guided bone regeneration (GBR) of peri-implant defects leads to different dimension of the augmented hard tissue than particulate bone substitute. Material & methods: In 40 patients, 40 two-piece dental implants were placed >2 months after tooth extraction. Following random allocation...
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The management and prevention of soft tissue complications is of key importance in modern implant dentistry and influences biologic and esthetic outcomes. The assessment of the soft tissue conditions from a quantitative and qualitative perspective should, therefore, be part of the overall treatment plan. Such an assessment dictates a potential indi...
Article
Aim: The aim of this study was to identify the additional effects of collagen membrane (CM) and of synthetic bone substitute (BS) on lateral bone augmentation of chronic peri-implant defect with titanium mesh (TM). Materials and methods: Atrophic alveolar ridge was induced in 6 canine mandibles and 5 peri-implant defects were achieved in each he...
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Objectives: To compare screw-retained and cemented all-ceramic implant-supported single crowns regarding biological and technical outcomes over a 5-year observation period. Materials and methods: in 44 patients, 44 two-piece dental implants were placed in single tooth gaps in the esthetic zone. Patients randomly received a screw-retained (SR) or...
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Objectives: To assess clinical, technical, biological, and radiographic outcomes of implants supporting fixed restorations using two types of dental implants with non-matching implant-abutment junctions at 8 years. Materials and methods: Sixty-four patients were randomly assigned to receive one of two implant systems (S1 or S2) and eventually fi...
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Objectives: to compare cemented and screw-retained one-piece zirconia-based restorations in terms of clinical, radiographic and technical outcomes 5 years after insertion. Materials and methods: Thirty-four patients with single-tooth implants were randomly restored with either a cemented lithium disilicate crown on a one-piece customized zirconi...
Conference Paper
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Background: Emerging evidence suggests that the prosthetic design of implant-supported crowns, namely restorative angles may have an impact on peri-implant marginal bone remodeling, but studies supporting this hypothesis are lacking. Whether this hypothesis applies to Ti Bases remains unknown. Aim/Hypothesis: To assess whether or not the restora...
Article
This study aimed to simultaneously assess hard and soft tissues alterations and their proportions after alveolar ridge preservation (ARP). Participants (n = 65) who were previously enrolled in a clinical trial investigating ARP healing were selected. The CBCT DICOM (Digital Imaging and Communications in Medicine) and the cast STL (stereolithographi...
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Objectives To assess long-term outcomes of implants placed in conjunction with guided bone regeneration (GBR) with or without recombinant human bone morphogenetic protein-2 (rhBMP-2). Materials and Methods 11 patients with at least two lateral bone defects (split-mouth design) received a total of 34 implants. The defects were treated with a xenoge...
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Purpose: This study was conducted to assess the effect of hard and/or soft tissue grafting on immediate implants in a preclinical model. Methods: In 5 mongrel dogs, the distal roots of P2 and P3 were extracted from the maxilla (4 sites in each animal), and immediate implant placement was performed. Each site was randomly assigned to 1 of the fol...
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Statement of problem The implant abutment connection interface has been considered one of the major factors affecting the outcome of implant therapy. However, drawbacks of traditional meta-analyses are the inability to compare more than 2 treatments at a time, which complicates the decision-making process for dental clinicians, and the lack of a ne...
Article
Aim To compare tissue changes at implant sites previously treated with two biomaterials for alveolar ridge preservation (ARP) in the esthetic zone, one year after restoration. Materials and Methods Sixty-six participants were treated with ARP using demineralized bovine bone mineral (DBBM) or DBBM + 10% of collagen (DBBM-C) both covered with a coll...
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Objective: To analyze the clinical outcomes of all-ceramic single crowns (SCs) and fixed dental prostheses (FDPs) supported by ceramic implants. Materials and methods: Based on a focused question and customized PICO framework, electronic (Medline/EMBASE/Cochrane) and manual searches for studies reporting the clinical outcomes of all-ceramic SCs...
Article
Aim To assess the effect of Schneiderian membrane (SM) perforation on bone formation by applying a particulate deproteinized bovine bone mineral (PBBM). Materials and Methods Bilateral sinus augmentation was performed in eight rabbits. The same amount of PBBM was placed at a sinus where the SM was intentionally perforated for the perforation group...
Article
OBJECTIVES The task of working Group 2 at the 6th Consensus Meeting of the European Association for Osseointegration was to comprehensively assess the effects of soft tissue augmentation procedures at dental implant sites on clinical, radiographic and patient-reported outcome measures (PROMs) including an overview on available outcome measures and...
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Objectives To test whether or not primary bone augmentation using xenograft blocks infused with BMP-2 or autogenous bone blocks leads to similar results regarding implant survival and 3D marginal soft tissue contours. Methods Twenty-four patients with an insufficient ridge width for implant placement in need of primary augmentation were randomly a...
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Aim The aim was to evaluate the performance of implants placed with simultaneous guided bone regeneration (GBR) using resorbable or non-resorbable membranes compared to implants placed in pristine bone without bone regeneration after an observation period of 22-24 years. Material and Methods The patient cohort of this clinical trial was treated fr...
Article
Objectives To assess the osseointegration of calcium-coated (CS) and chemically modified, sandblasted, large-grit, acid-etched (MS) dental implants with a lack of primary mechanical stability. Materials and Methods Eighteen implants in CS and MS groups each were loosely placed in the mandible of 6 mongrel dogs and allowed to heal for 2, 4 and 8 we...
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Purpose To test whether or not alveolar ridge preservation (ARP) changes the clinical attachment level (CAL) at adjacent teeth of extraction sockets after 6 months. Material and methods Seventeen patients requiring bilateral tooth extractions of the upper molars were recruited. After tooth extraction, the sockets were randomly allocated to two gro...
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Objectives To test whether or not the use of a short implant with a cantilever results in similar clinical and radiographic outcomes compared to two adjacent short implants with single tooth reconstructions. Material and Methods Thirty-six patients with two adjacent missing teeth in the posterior region were randomly assigned to receive either one...
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Objectives To test whether early implant placement with alveolar ridge preservation (ARP) results in different esthetic, clinical and patient-reported outcome measures (PROMs) compared to early implant placement without ARP. Material and Methods Seventy-five patient requiring single tooth extraction in the anterior maxilla were recruited. Followin...
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Objectives To compare free-hand to computer-assisted implant planning and placement (CAIPP) regarding planned to achieved implant position. Materials and methods Forty-eight cast/bone models were mounted in mannequin heads. On each side, a tooth gap of different size was created. In the test group (T), study implants were placed using a CAD-CAM gu...
Article
Objectives : The aim of this retrospective clinical study was to investigate the survival rate, technical and biologic complications of leucite-reinforced glass-ceramic crowns after a follow-up time of 13-15 years. Material and Methods : Fifty-three patients with 131 crowns were invited to the follow-up visit. The reconstructions were re-examined...
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Objectives The task of working Group 2 at the 6th Consensus Meeting of the European Association of Osseointegration was to comprehensively assess the effects of soft tissue augmentation procedures at dental implant sites on clinical, radiographic, and patient-reported outcome measures (PROMs) including an overview on available outcome measures and...
Article
Evidence on the use of short dental implants has substantially increased in recent years. Consequently, short dental implants have expanded treatment options. Specific clinical indications currently encompass sites with a limited ridge height due to nearby anatomical structures: the maxillary sinus or the alveolar nerve in the lower jaw. In compari...
Article
Objectives To assess clinical and radiographic outcomes as well as the profilometric contour alterations of peri‐implant hard and soft tissues around single implants treated with simultaneous guided bone regeneration (GBR) at 5 years. Materials and methods Twenty‐seven patients presenting with a single tooth gap in the esthetic zone received a two...
Article
Background: Although 5-year clinical data exist for different zirconia implants, no analysis has yet been performed focusing on how the surface topography of the implant affects clinical parameters. Purpose: To analyze the influence of zirconia implant topography on first bone implant contact (fBIC). Materials and Methods: In a prospective two-cent...
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AimTo assess histopathological and histomorphometric outcomes of soft tissue volume augmentation procedures at pontic sites using a volume-stable cross-linked collagen matrix (VCMX) and a non-cross-linked collagen matrix (XCM).Materials and methodsIn twelve adult beagle dogs, the mandibular premolars and first molar were hemisected and the mesial r...
Article
Purpose: To assess the clinical, technical, and esthetic outcomes of directly veneered zirconia abutments cemented onto non-original titanium bases over 3 years. Materials and methods: A total of 24 healthy patients with a single missing tooth in the maxilla or mandible (incisors, canines, or premolars) received a two-piece implant with a screw-...
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Objectives To assess contour changes of peri-implant tissues comparing a one- and a two-piece dental implant system over 12 years. Materials and methods Patients seeking implant therapy were enrolled and randomly allocated to receive implants (a one-piece (STM) or a two-piece (BRA) system). Impressions were taken at the time of insertion of the fi...
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Objective To compare the clinical, radiographic, and histological healing patterns between the immediate and delayed applications of bone morphogenetic protein-2 (BMP-2) in damaged extraction sockets in dogs.Materials and methodsThe distal roots of the fourth premolars of the mandible were extracted bilaterally in five beagle dogs, and buccal bone...
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Objectives To analyze the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants. Methods Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position randomized. At 3 months, half of the patients were in...
Article
Objectives To quantify the neighboring and antagonist teeth migration of a single posterior tooth‐missing site within three months using digital scanning and measuring techniques. Material and Methods Intraoral scans (IOS) were made in 40 patients presenting a single posterior tooth‐missing gap and receiving implant therapy. IOS were obtained at t...
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Purpose: To investigate the effect of aging on the morphology of the interface between monolithic implant crowns and standardized titanium base abutments. Materials and methods: Four groups of hybrid abutment crowns differing in restorative material (lithium disilicate [LD] or polymer-infiltrated ceramic network [PICN]) and in fabrication proced...
Article
OBJECTIVES The aim of the present randomized, controlled clinical multicenter trial was to compare a polyethylene glycol (PEG) and a native collagen membrane (BG) for simultaneous guided bone regeneration at bony dehiscence-type defects around bone level titanium implants. MATERIAL AND METHODS The study enrolled 117 patients requiring implant treat...
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Objectives To compare two ridge preservation techniques and spontaneous healing in terms of hard and soft tissue changes 2 months after tooth extraction. Material and Methods The study was designed as a randomized controlled trial and included 75 patients. After single tooth extraction in the maxillary incisor/premolar area, patients were randomly...
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Objectives: To investigate in vitro release kinetics and ossification patterns of bone morphogenetic protein-2 soaked collagenated porcine bone mineral (BMP-2/CPBM) in rabbit sinuses. Methods: Release kinetics of BMP-2/CPBM was determined in vitro up to 56 days. In 16 rabbits, BMP-2/CPBM (BMP group) and CPBM alone (control group) were bilaterall...