Robert J Smith's research while affiliated with University of Ottawa and other places

... This hypothesis led Church and Smith? [5] to pose the following question: "Is it always safe to assume that sufficiently short processes occur instantaneously?" They found that this is not always true, albeit for a limited class of equations. ...

... Gene resistance control cannot be widely used due to its high cost, and vector control through insecticide spraying has a small risk of failure due to selection for more damaging virus strains [14][15][16]. However, the cultural control including roguing or removal of diseased plants has been practised and could be more effective [17][18][19][20]. erefore, a successful plant disease control program depends on a plant production system which is closely aligned with the goals of pest management [21][22][23]. ...

... The most common intervention considered is vaccination or monoclonal immunoprophylaxis that induces full temporary immunity to RSV infection (Acedo et al. 2010a, b;Brand et al. 2020;Goldstein et al. 2018;Hodgson et al. 2020;Jornet-Sanz et al. 2017;Kinyanjui et al. 2015;Nugraha and Nuraini 2017;van Boven et al. 2020); however, vaccination inducing partial temporary immunity to RSV infection Kinyanjui et al. 2020;Pan-Ngum et al. 2017;Smith et al. 2017;Yamin et al. 2016), public awareness campaigns (Nugraha and Nuraini 2017), and treatment (Rosa and Torres 2018a, b), are also considered. Interventions are generally assumed to occur uniformly throughout the year, however, exceptions include models that assume vaccination occurs at arbitrary time points throughout the year (Smith et al. 2017), seasonally according to the pattern observed in influenza vaccination (Yamin et al. 2016), at enrollment of primary school (Poletti et al. 2015), and prior to the RSV season (Goldstein et al. 2018;Hodgson et al. 2020). ...

... Many mathematical models have been developed to describe the effect of the entry inhibitors on HIV progression. Mathematical models in [11,14] suggest that a combination of fusion inhibitors (enfuvirtide) and protease inhibitors gives a better outcome than single-drug activity in suppressing the viral load and inhibiting viral entry into the host cell. Magombedze et al. [48] developed mathematical models of the immuno-pathogenesis of HIV infection by incorporating three different stages of the HIV replication cycle: viral entry, transcription from viral RNA to DNA, and production of HIV viral particles to study the effect of their inhibitors. ...

... Early evaluations indicated that malaria transmission had dropped considerably, resulting in a 60% reduction in child mortality following the first 4 years of interventions [12], and a corresponding 50% drop in parasite prevalence in children aged between 1 and 14 years [13]. However, despite its island status, a study in 2013 demonstrated that travel to the mainland of Equatorial Guinea increased the risk of infection in travellers themselves, and in non-travellers living in neighbourhoods with high proportions of travellers [14], highlighting the impact of population movement on malaria transmission levels [15][16][17][18]. ...

... The theory of impulsive differential equations and inclusions has been systematically developed (see e.g., the monographs [1][2][3][4], and the references therein), among other things, especially because of many practical applications (see e.g., References [1,[4][5][6][7][8][9][10][11]). These applications concern fluctuations of pendulum systems under impulsive effects, remittent oscillators, population dynamics, oxygen-driven self-cycling fermentation process, nutrient-driven self-cycling fermentation process, various impulsive drug effects, optimal impulsive vaccination for an SIR control model, an SEIRS epidemic model, malaria vector model, impulsive insecticide spraying, HIV induction-maintenance therapy, and so forth. ...

... Although mathematical modelling investigations into H5N6 are infrequent, there have been a handful of analyses that estimate various subtypes of avian influenza for poultry and human activities [5,6]. Several studies have chosen to use bilinear recurrence estimates to investigate avian influenza propagation, including bird and human populations, for accessibility [7]. ...

... For instance, when disease occurs, people pay more attention to personal hygiene (frequent hand washing, wearing masks, consuming safe drinking water), choose to prevent it through antibiotics, change their travel routes to stay away from areas with high disease prevalence, and thus achieve a reduced risk of contracting the disease. Recently, mathematical epidemiological models on the influence of human behavior have become increasingly available [1,3,10,12,48,51,52]. ...

... While each jurisdictional program has undergone a series of policy changes, program information is scattered across multiple sources and there is no national database that compiles this information. There have been several descriptions of HPV vaccination programs [5][6][7][8], but no analysis of the evolution of HPV vaccination policies and vaccination coverage in all Canadian jurisdictions. As Canada prepares to implement the prevention strategies designed to meet the World Health Organization's goal of eliminating cervical cancer [8], it is essential that Canadian policymakers take stock of the current status of HPV vaccination. ...

... Ciupe et al. [7] studied a model for EIAV strains and neutralizing antibodies. Schwartz et al. [8] derived a model for EIAV to predict the condition to eradicate the wild-type infection with antibody infusions. ...