Robert H. Hawes's research while affiliated with Florida Hospital and other places

Publications (317)

Article
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Background and Aims Consensus regarding an optimal algorithm for endoscopic treatment of papillary adenomas has not been established. We aimed to assess the existing degree of consensus among international experts and develop further concordance by means of a Delphi process. Methods A total of 52 international experts in the field of endoscopic pa...
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It has been 10 years since peroral endoscopic myotomy (POEM) was reported for the first time, and POEM has currently become the standard treatment for achalasia and related disorders globally because it is less invasive and has a higher curative effect than conventional therapeutic methods. However, there are limited studies comparing the long-term...
Article
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Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during which a VLE scan was performed. The objective of this registry was to determine usage patterns...
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Background: Endoscopic sutured gastroplasty (ESG) has evolved over time. With the advent of full-thickness endoscopic suturing, an efficient technique for ESG was developed and refined. Methods: This prospective first-in-man trial started in April 2012 and represents the first use of full-thickness endoscopic suturing for primary obesity therapy...
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Objectives Interventional endoscopic ultrasonography (EUS) procedures are gaining popularity and the most commonly performed procedures include EUS-guided drainage of pancreatic pseudocyst, EUS-guided biliary drainage, EUS-guided pancreatic duct drainage and EUS-guided celiac plexus ablation. The aim of this paper is to formulate a set of practice...
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Opinion statement: Purpose of Review Gastrointestinal stromal tumors (GISTs) are both relatively common. Management of these lesions has been challenging with emerging interest in the endoscopic approach for both diagnostic and therapeutic interventions. Recent Findings Although these can be visualized on CT scan, endoscopic ultrasound (EUS) repre...
Article
Objective: To study the effect of disconnected pancreatic duct syndrome (DPDS) on endoscopic management of pancreatic fluid collections (PFCs). Background: Data on the impact of DPDS in patients undergoing endoscopic treatment of PFCs are limited. Methods: Retrospective study of patients undergoing endoscopic drainage of PFCs from 2003 to 2015...
Article
Background and aim: Recently, a 22 gauge (G) needle with a Franseen tip design was developed for EUS-guided fine needle biopsy (EUS-FNB). This study evaluated the performance of the Franseen biopsy needle in EUS-guided tissue acquisition. Methods: This is a retrospective study of patients who underwent EUS-FNB using the Franseen needle. Lesions...
Conference Paper
Introduction: Endoscopic mucosal resection (EMR) for duodenal lesions is an appealing alter- native to surgical resection. However, the duodenum is considered a challenging and high-risk site for endoscopic interventions. Herein, we report a single-center 2-year experience of perform- ing duodenal EMR to assess its therapeutic outcomes. Aim: Evalua...
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Background and study aims: Although the diagnostic features of disconnected pancreatic duct syndrome (DPDS) by computed tomography (CT) and magnetic/endoscopic retrograde cholangiopancreatography (MRCP/ERCP) have been established, no such characterization exists for endoscopic ultrasound (EUS). This study describes the imaging features of EUS that...
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Aim: The aim of this article is to evaluate the clinical and cost implications of failed endoscopic hemostasis in patients with gastroduodenal ulcer bleeding. Methods: A retrospective claims analysis of the Medicare Provider Analysis and Review (MedPAR) file was conducted to identify all hospitalizations for gastroduodenal ulcer bleeding in the...
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Background and aims: Data on the safety and efficacy of endoscopic resection of non-ampullary duodenal polyps are limited. This study evaluated the safety and efficacy of endoscopic mucosal resection (EMR) of sporadic non-ampullary duodenal polyps. Methods: Relevant studies for the meta-analysis were identified through search of PUBMED and EMBASE d...
Article
Background and aim: Tissue diagnosis, regardless of technique or endoscope used, can be challenging in patients with indeterminate bile duct strictures (IDBS). This exploratory study evaluated the utility and role of rapid onsite evaluation of touch imprint cytology (ROSE-TIC) when performing single-operator cholangioscopy (SOC)-guided biopsies of...
Article
Background and aim: Although EUS-guided celiac plexus neurolysis (EUS-CPN) is frequently performed for palliation of pain in pancreatic cancer, response to treatment is variable. Although intra-procedural increase in heart rate during alcohol injection is frequently observed, its significance and relationship to treatment outcome is unknown. The o...
Article
Background: Endoscopic ultrasound (EUS) is considered the most sensitive modality for local staging of esophageal cancer (ECA) and current guidelines recommend EUS in all patients with non-metastatic disease. Our aim was to identify a subset of patients with stenotic, non-metastatic ECA who will not benefit from staging EUS. Methods: This multi-...
Article
Evaluation of indeterminate biliary strictures by brush cytology and intraductal biopsies is limited by low sensitivity. The utility of SpyGlass peroral cholangioscopy for diagnosis of malignant biliary strictures and cholangiocarcinoma (CCA), in particular, remains unclear. Our aim was to study the utility of SpyGlass peroral cholangioscopy and ta...
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Detection of hepatic metastases during EUS is an important component of tumor staging. To describe our experience with EUS-guided FNA (EUS-FNA) of solid hepatic masses and derive and validate criteria to help distinguish between benign and malignant hepatic masses. Retrospective study, survey. Single, tertiary-care referral center. Medical records...
Article
A major reason impeding the growth of endoscopic ultrasound (EUS) in Asia is the lack of training availability. We aimed to prospectively evaluate the effectiveness of short-term structured EUS training program in improving the knowledge and skill of EUS among trainees. The study was conducted in 6 workshops in 6 countries including Sri Lanka, Paki...
Article
Background The aim of the study was to compare the outcomes of patients with pancreatic or peripancreatic walled-off necrosis by endoscopy using the conventional approach versus an algorithmic approach based on the collection size, location and stepwise response to intervention.Methods This was an observational before–after study of consecutive pat...
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Objectives Although a large gauge needle can procure more tissue at endoscopic ultrasound-guided fine needle aspiration (EUS-FNA), its advantage over smaller needles is unclear. This study compared flexible 19G and 25G needles for EUS-FNA of solid pancreatic masses. Methods This was a randomized trial of patients undergoing EUS-FNA of pancreatic m...
Article
Background: Although on-site cytopathology services have a significant impact on efficiency and accuracy of EUS-guided FNA (EUS-FNA), the availability of this service is variable. Objective: To evaluate the impact of an intensive 2-day training program to educate endosonographers in EUS-related cytopathology. Design: Pilot study. Setting: Te...
Article
Background: The over-the-scope clip (OTSC) provides more durable and full-thickness closure as compared with standard clips. Only case reports and small case series have reported on outcomes of OTSC closure of GI defects. Objective: To describe a large, multicenter experience with OTSCs for the management of GI defects. Secondary goals were to d...
Article
Overall, Digestive Disease Week (DDW) 2013 was an excellent year for endoscopic innovation. For this section, the abstracts have been divided into new technologies and new techniques. The abstracts selected for review are ones that represent material that has a reasonable chance of affecting the practice of GI endoscopy.
Article
Barrett esophagus is characterized by the replacement of squamous mucosa in the esophagus by specialized intestinal metaplasia. Its clinical significance lies in it being the strongest risk factor for and known precursor for esophageal adenocarcinoma. Diagnosis requires endoscopic confirmation of columnar metaplasia in the distal esophagus and hist...
Article
Background White light endoscopy with random biopsies is the standard for detection of intestinal metaplasia (IM) and neoplasia in patients with Barrett's oesophagus (BO). Narrow band imaging (NBI) highlights surface patterns that correlate with IM and neoplasia in BO. Objective To compare high-definition white light (HD-WLE) and NBI for detection...
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The Rosemont criteria (RC) were recently proposed by expert consensus to standardize endoscopic ultrasound (EUS) features and thresholds for diagnosing chronic pancreatitis (CP); however, they are cumbersome and are not validated. To determine interobserver agreement between RC and conventional criteria (CC), and to assess intertest agreement in th...
Article
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been recognized worldwide as a useful modality to enhance the accuracy of biopsy, diagnosis and treatment of lesions with few complications, since Vilmann reported the first procedure. In this article, the learning tools, indications and contraindications, essential anatomy, sedation...
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Background When the concept of Natural Orifice Transluminal Endoscopic Surgery (NOTES (TM)) was first introduced, many physicians could envisage its potential as a less invasive and more cosmetic way to perform surgery. The potential for harm if NOTES was adopted too rapidly was also readily apparent. To ensure the responsible development of these...
Article
EUS-FNA has limitations in cancer diagnosis/staging. New contrast agents, transducers, and processors have improved the potential of contrast-enhanced harmonic (CEH)-EUS. To determine optimal settings and preliminary accuracy of CEH-EUS by using a second-generation perflutren lipid microsphere contrast agent and a prototype linear echoendoscope. Pr...
Book
Endosonography-by Drs. Robert H. Hawes, Paul Fockens, and Shaym Varadarjulu-is a rich visual guide that covers everything you need to effectively perform EUS, interpret your findings, diagnose accurately, and choose the best treatment course. World-renowned endosonographers help beginners apply endosonography in the staging of cancers, evaluating c...
Article
Although endoscopic plastic biliary stenting is a clinical procedure routinely carried out in patients with common bile duct stones, the effects of stenting on the sizes or fragmentation of large common bile duct stones have not been formally established and the mechanism of this condition is controversial. We compared the stone sizes of common bil...
Article
Idiopathic chronic pancreatitis (ICP) is a complex inflammatory disorder associated with multiple genetic and environmental factors. In individuals without cystic fibrosis (CF), variants of CFTR that inhibit bicarbonate conductance but maintain chloride conductance might selectively impair secretion of pancreatic juice, leading to trypsin activatio...
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The impact of the diagnosis and treatment of dysplastic Barrett's esophagus on quality of life (QoL) is poorly understood. This study assessed the influence of dysplastic Barrett's esophagus on QoL and evaluated whether endoscopic treatment of dysplastic Barrett's esophagus with radiofrequency ablation (RFA) improves QoL. We analyzed changes in QoL...
Article
Adhesions are common after conventional surgery; natural orifice transluminal endoscopic surgery (NOTES) avoids peritoneal disruption and may reduce adhesions. To determine whether adhesions (and peritoneal contamination) are less common with NOTES transgastric colon injury and repair (TGCR) than with laparoscopic colon repair (LCR). Porcine surviv...
Article
Practical Gastrointestinal Endoscopy has become the basic primer for endoscopy around the world. This new edition has been thoroughly revised and updated. Drawing on the vast experience of the authors it provides clear and practical guidance on the fundamentals of standard endoscopy practice. It describes procedures in great depth and addresses imp...
Article
The Plicator (NDO Surgical, Inc., Mansfield, MA) endoscopically places a full-thickness permanent suture to augment the antireflux barrier. At 3-years post-treatment, published results demonstrated a reduction in subjects' gastroesophageal reflux disease (GERD) symptoms and related medication use. To evaluate the Plicator's safety and durability of...
Article
Reliable closure of the transluminal incision is the crucial step for natural orifice transluminal endoscopic surgery (NOTES) procedures. The aim of this study was to evaluate the feasibility and effectiveness of transgastric access closure with a flexible stapling device in a porcine survival model. We carried out four experiments (two sterile and...
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The most permanent method of treating achalasia is a surgical myotomy. Because of the requirement for a mucosal incision and the risk of perforation, this procedure has not generally been approached endoscopically. We hypothesized that we could perform a safe and robust myotomy by working in the submucosal space, accessed from the esophageal lumen....
Article
Technical options for pancreatic sphincterotomy of the minor papilla for pancreas divisum include a needle-knife cut over a plastic stent and a standard pull-type cut with a sphincterotome. Our objective was to compare the frequency, safety, and intermediate-term efficacy of these 2 techniques at our institution. Retrospective review of the GI-Trac...
Article
There are a number of options to assist the trainee to achieve competency in EUS and EUS-FNA. Although no randomized controlled trial with these tools have been performed to definitely determine their role in training, this survey of EUS experts suggest they can have a positive role. The authors believe that it is critically important to develop pr...