Revanth Kishore Pulamolu’s research while affiliated with Sam Higginbottom University of Agriculture, Technology and Sciences and other places

The medicinal properties of plants stem from specific compounds known as plant secondary metabolites, which possess significant potential in treating various human ailments and diseases. However, these metabolites are typically produced in small quantities naturally as a response to different stresses. To address this limitation, researchers explore ways to enhance the production of these valuable metabolites. Biotechnological methods offer numerous advantages, such as consistent, stable, and year-round sustainable production, scalability, and simplified extraction and purification processes. Techniques like hairy root, callus, and suspension cultures are reliable approaches for producing these bioactive compounds in controlled environments. Additionally, ongoing research explores genetic engineering, metabolic engineering, and biotransformation as promising methods to boost biomass and biochemicals. Notably, recent studies highlight the use of elicitors from both biotic and abiotic sources, with nanoparticle elicitation garnering significant attention among researchers. This chapter aims to summarize the latest advancements in the in vitro production of high-value plant secondary metabolites with medicinal significance.