Reuben Brasher's research while affiliated with Microsoft and other places
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Publications (5)
In Escherichia coli DNA replication yields interlinked chromosomes. Controlling topological changes associated with replication and returning the newly replicated chromosomes to an unlinked monomeric state is essential to cell survival. In the absence of the topoisomerase topoIV, the site-specific recombination complex XerCD- dif-FtsK can remove re...
In Escherichia coli DNA replication yields interlinked chromosomes. Controlling topological changes associated with replication and returning the newly replicated chromosomes to an unlinked monomeric state is essential to cell survival. In the absence of the topoisomerase topoIV, the site-specific recombination complex XerCD- dif -FtsK can remove r...
The knot nomenclature in common use, summarized in Rolfsen's knot table [Rolfsen (1990) Knots and Links, American Mathematical Society], was not originally designed to distinguish between mirror images. This ambiguity is particularly inconvenient when studying knotted biopolymers such as DNA and proteins, since their chirality is often significant....
Citations
... Tangles have had various applications in knot theory and biology. Notably, tangles have been used to model enzyme actions on DNA [19,46,9]. This paper presents an application of tangle calculus to the study of protein knotting. ...
Reference: Modeling knotted proteins with tangles
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272365108068359-1441948310225_Q64/Mariel-Vazquez.jpg)
... It is important to note in context of nomenclature of chiral knots, when it comes to distinguishing of a knot from its chiral pair, the current tables are ambiguous and choice of a representative of the chiral pair is often inconsistent [94]. When identifying a knot, one usually compares it with the Rolfsen's table [95], while the representative of the chiral pair in the table is often marked with a prefix "+" and the sign "−" is used for its mirror image. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272825382600745-1442058048869_Q64/Robert-Scharein.jpg)
