René Voyer’s research while affiliated with Université de Montréal and other places

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Publications (14)


Do Postoperative Antibiotics Influence One‐year Peri‐implant Crestal Bone Remodeling and Morbidity? A Double‐blinded Randomized Clinical Trial
  • Article
  • Full-text available

September 2021

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53 Reads

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6 Citations

Clinical Oral Implants Research

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Issam Kersheh

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Stéphanie Marcotte

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[...]

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René Voyer

Objectives The primary objective of this study was to assess whether giving postoperative antibiotics to healthy patients after straightforward platform-switched implant placement would influence peri-implant crestal bone levels and postoperative morbidity after one year. Methods Thirty-eight healthy individuals were recruited in this pilot, randomized, double-blinded, placebo-controlled clinical trial. The intervention group (n=18) received two grams of amoxicillin one hour before implant placement followed by a seven-day postoperative regimen (500 mg tid). The control group (n=20) took the same preoperative dose of amoxicillin and an identical placebo postoperatively. Mesial and distal peri-implant crestal bone levels were measured at baseline, four months and one year later with standardised periapical radiographs. Postoperative pain severity was assessed through self-administered questionnaires for seven days. Surgery-associated morbidities were evaluated after one, three, 16 weeks and one year. Descriptive and bivariate analyses were used. Results Thirty-seven participants completed the trial. At the one-year follow-up, the mean combined peri-implant crestal bone changes for the intervention (n=18) and control (n=19) groups were - 0.44 ± 0.41 mm and - 0.27 ± 0.56 mm, respectively. The difference between the groups (intervention-control) for mean combined crestal bone level changes was not statistically significant. There were no significant differences in surgery-associated morbidities between the intervention and control groups. The one-year implant survival rate was 100% in both groups. Conclusions Study results suggest that a routine postoperative antibiotic regimen for healthy patients undergoing straightforward platform-switched implant placement might not be necessary to prevent postoperative peri-implant bone loss and complications.

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Measurements to evaluate alveolar bone thickness and height taken through the CBCT buccolingual section of the tooth. Abbreviations are described in Table 1
Alveolar bone thickness changes, crest height loss and root resorption following OT-PC assessed from the mesial of the 1st molar to the contralateral tooth in both the maxilla and mandible. Differences between post- and pre-treatment values were calculated in mm; therefore a negative value corresponds to a post-treatment decrease. ‡ data did not follow the normal law therefore a one sample Wilcoxon test was used and the median with inter quartile range (IQR) was expressed. For others variables, a one sample t-test was used and the mean with the standard deviation (SD) was expressed. % = percentage of site with completely alveolar bone dehiscence after OT-PC. * = 0.05 > P > 0.01; ** = 0.01 ≥ P > 0.001; *** = P ≤ 0.001
Impact of piezocision-assisted orthodontics on root resorption and alveolar bone: a prospective observational study

July 2021

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325 Reads

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7 Citations

Objectives To assess the impact of orthodontic treatment combined with piezocision (OT-PC) on root structure and alveolar bone.Materials and methodsTwelve adults were treated with OT-PC. Pre- and post-treatment CBCT examinations evaluated apical root resorption (ARR) and alveolar bone height and thickness changes. Pre- and post-treatment differences were compared using one-sample t test and Wilcoxon signed-rank test.ResultsARRs were generalized and significantly more severe in both anterior sextants compared with posterior sextants. Bone thickness decreased significantly in the maxilla at mid-root and apex areas. The majority of mandibular alveolar bone dehiscences occurred on the buccal aspect at the mid-root level, especially where thickness was less than 0.3 mm. Overall bone height decreased twice as much on the buccal aspect (1.43 mm, P < 0.001) compared with the lingual aspect (0.67 mm, P = 0.001), most significantly in the lower incisors, where the average median loss was 2.10 mm (P = 0.003).ConclusionOT-PC causes minor negative effects on both alveolar bone and root resorption.Clinical relevanceOrthodontic treatment combined with piezocision causes minor negative effects on periodontal support. Nevertheless, mild bone height loss on the buccal aspect of the mandibular teeth and root resorption in both anterior sextants have been detected with this new treatment.


Dental caries are positively associated with periodontal disease severity

October 2019

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123 Reads

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39 Citations

Objectives To examine associations between periodontal disease severity and clinical and microbiological measures of caries in adults. Materials and methods A cross-sectional study of 94 healthy adults ((mean ± SD) 55.4 ± 13.0 years) was conducted. Data were collected by means of questionnaire and a clinical examination that included the Decayed, Missing, Filled teeth Surfaces (DMFS) index, probing depth (PD), clinical attachment level (CAL), and gingival bleeding and plaque scores. Supra- and subgingival plaque samples were collected to assess the presence of Streptococcus mutans and six periodontal pathogens. Participants were subsequently categorized using Center for Disease Control and Prevention/American Academy of Periodontology (CDC-AAP) definitions and tertiles of percentage of sites with CAL ≥ 3mm. Results Significant positive associations were found between the periodontal disease severity (CDC-AAP) and the DMFS (aOR = 1.03; 95% CI 1.01–1.05) and DS indices (aOR = 1.18; 95% CI 1.05–1.32) as well as between the tertiles of percentage of sites with CAL ≥ 3 mm and DMFS (aOR = 1.03; 95% CI 1.00–1.05) and DS indices (aOR = 1.12; 95% CI 1.00–1.25). A significant positive association was also found between oral levels of F. nucleatum and S. mutans (aOR = 6.03; 95% CI 1.55–23.45). Conclusions A small but positive association was found between clinical measures of caries and periodontal disease severity. Further research is warranted to examine the association between these two common oral diseases. Clinical relevance Periodontal diseases and caries are the two most common oral diseases. There was a positive association between clinical and microbiological markers of both diseases. Therefore, strategies in oral health education should involve both caries and periodontitis prevention.


Piezocorticision-assisted orthodontics: Efficiency, safety, and long-term evaluation of the inflammatory process

May 2019

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109 Reads

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18 Citations

American Journal of Orthodontics and Dentofacial Orthopedics

Objectives: The aim of this work was to compare the duration of treatment between orthodontic treatment combined with piezocorticision (OT-PC) and conventional orthodontic treatment (COT), as well as to evaluate the safety, inflammatory process, periodontal health, and soft tissue healing in the OT-PC group. Methods: Twelve patients were included in each group, and their treatment times were compared for preliminary bracket alignment (PBA) and for overall treatment. In the OT-PC group, the inflammatory process was evaluated by quantifying cytokines in the gingival crevicular fluid. A calibrated examiner measured the probing depth (PD), the distance between the gingival margin and the cementoenamel junction (GM-CEJ), and the clinical attachment level (CAL), before and after OT-PC. The presence of gingival scars was evaluated. Bone and root injuries were assessed with the use of cone-beam computed tomography. Results: The treatment time was significantly reduced in the OT-PC group for PBA in both maxilla (45%; P = 0.001) and mandible (31%; P = 0.023), as well as for overall treatment (52%; P < 0.0001). Although not statistically significant, several inflammatory mediators demonstrated peaks at 3-5 and 16 weeks. There were not significant changes in PD and GM-CEJ after OT-PC treatment, unlike CAL (0.09 ± 0.12 mm; P = 0.024); 47.5% of piezocorticisions caused gingival scars. Only one patient showed no scars. Four cortical bones did not heal completely, and 2 roots had piezoelectric injuries. Conclusion: OT-PC was effective at reducing the orthodontic treatment time.


Step-by-Step Surgical Considerations and Techniques

March 2018

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93 Reads

The management of the edentulous patient may represent a challenge in implantology for most surgeons. Careful planning using evidence-based methods will not only facilitate the surgical intervention but might also greatly improve the long-term prognosis of implant-supported prostheses. In this chapter, the anatomy of the mandible with a surgical perspective is reviewed in detail. The pre-, intra-, and postoperative elderly patient management including strategies to reduce anxiety, risk, and morbidity is reviewed. Mucogingival considerations, keratinized gingiva augmentation procedures, and steps for optimal implant placement are illustrated with clinical cases. Detailed pre- and postoperative instructions are presented as well as management of common surgical and postsurgical complications.


Fig. 1 Strategies for integration of oral health into primary care based on the Valentijn et al. integration framework 
Table 1 Integration of oral health into primary care: Summary of integrated oral health care programmes 
Fig. 2 Flowchart of the scoping review 
From theoretical concepts to policies and applied programmes: The landscape of integration of oral health in primary care

February 2018

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513 Reads

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60 Citations

BMC Oral Health

Background Despite its importance, the integration of oral health into primary care is still an emerging practice in the field of health care services. This scoping review aims to map the literature and provide a summary on the conceptual frameworks, policies and programs related to this concept. Methods Using the Levac et al. six-stage framework, we performed a systematic search of electronic databases, organizational websites and grey literature from 1978 to April 2016. All relevant original publications with a focus on the integration of oral health into primary care were retrieved. Content analyses were performed to synthesize the results. ResultsFrom a total of 1619 citations, 67 publications were included in the review. Two conceptual frameworks were identified. Policies regarding oral heath integration into primary care were mostly oriented toward common risk factors approach and care coordination processes. In general, oral health integrated care programs were designed in the public health sector and based on partnerships with various private and public health organizations, governmental bodies and academic institutions. These programmes used various strategies to empower oral health integrated care, including building interdisciplinary networks, training non-dental care providers, oral health champion modelling, enabling care linkages and care coordinated process, as well as the use of e-health technologies. The majority of studies on the programs outcomes were descriptive in nature without reporting long-term outcomes. Conclusions This scoping review provided a comprehensive overview on the concept of integration of oral health in primary care. The findings identified major gaps in reported programs outcomes mainly because of the lack of related research. However, the results could be considered as a first step in the development of health care policies that support collaborative practices and patient-centred care in the field of primary care sector.



Integration of oral health into primary care: A scoping review protocol

October 2016

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197 Reads

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16 Citations

BMJ Open

Introduction Integrated care has been introduced as a means of improving health outcomes and access to care, and reducing the cost of healthcare. Despite its importance, the integration of oral health into primary care is still an emerging healthcare pathway. This scoping review protocol has been developed and funded by the Canadian Institutes of Health Research to provide an evidence-based synthesis on a primary oral healthcare approach and its effectiveness in improving oral health outcomes. Methods and analysis The 6-stage framework developed by Levac et al underpins this scoping review. We will identify relevant existing theories, programmes and original research through a comprehensive and systematic search of electronic databases such as OVID (MEDLINE, EMBASE, Cochrane databases), NCBI (PubMed), EBSCOhost (CINAHL), ProQuest, Databases in Public Health, Databases of the National Institutes of Health (health management and health technology) and relevant organisational websites and other sources of grey literature. All types of studies from 1978 to May 2016 in the French and English languages will be included. Using the Rainbow conceptual model of integrative primary care, a qualitative descriptive approach and thematic analysis will be used to synthesise the literature. Implementing novel healthcare models necessitates identifying barriers, sharing knowledge and delivering information. The integration of oral healthcare into primary care is an approach that promotes breaking the boundaries separating oral healthcare professionals and primary care. It creates opportunities for the dental workforce to become more involved in community-based practice and to assume shared responsibility with healthcare professionals to address the unmet oral health needs of those experiencing vulnerability and marginalisation. Ethics and dissemination The scoping study has received approval from the Université de Montréal's Institutional Review Board (#14–097-CERES-D). The findings will be disseminated through publications and presentations in provincial, national and international research symposiums and professional meetings.


[Association between oral conditions and colorectal cancer: A literature review and synthesis]

February 2016

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40 Reads

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5 Citations

Revue d Épidémiologie et de Santé Publique

Background: Chronic periodontitis and tooth loss are chronic oral conditions that, in recent decades, have been implicated in the occurence of certain types of cancer. In this review, we address the question of whether colorectal cancer is associated with these oral conditions. Results: Epidemiological studies evaluating a potential association between periodontitis, tooth loss and colorectal cancer are scarce. However, several mechanisms argue in favor of this association, notably inflammation, nutrition and possibly infection by specific bacteria, as suggested by this literature review.


Effectiveness of an alcohol-free essential oil-containing mouthwash in institutionalised elders receiving long-term care: A feasibility study

March 2014

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143 Reads

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11 Citations

Gerodontology

Objectives To conduct a feasibility study on investigating the effectiveness of an alcohol-free essential oil mouthwash (AF-EOMW) to reduce plaque accumulation and oral pathogen levels in institutionalised elders receiving long-term care and to obtain preliminary results. Background Although simple, cost-effective strategies to improve oral hygiene in seniors such as the use of mouthwashes have been shown to reduce the risks of respiratory diseases, little information is available on the feasibility of implementing these measures. Methods Twenty-five elderly participants with significant loss of autonomy were initially recruited and divided into two groups. A test group rinsed with an AF-EOMW twice a day, and a control group rinsed with tap water. Data on demographic characteristics, dental history and tobacco use were collected from a questionnaire. Problems encountered during recruitment and data collection were documented. Plaque index, denture cleanliness and salivary levels of several pathogens were measured at three time points: baseline (T0), day 22 (T1) and day 45 (T2). ResultsEighteen participants completed the study. Several problems were encountered during recruitment and execution of the study protocol. No significant differences in clinical or microbiological measures were found between the test group and controls at three time points (p > 0.05). Conclusion This pilot study shows that, if sufficient logistical and financial resources are available, it is feasible to conduct randomised clinical trials in a seniors' facility. The use of an AF-EOMW to improve oral hygiene in seniors was not found to be superior to tap water. However, larger controlled clinical studies are needed to confirm these results.


Citations (12)


... In one study, patients treated with postoperative antibiotics experienced greater peri-implant vertical bone loss up to the 6-month follow-up but showed less bone loss in subsequent intervals up to 60 months [39]. Another study on healthy patients undergoing implant surgeries without additional bone grafting found that systemic postoperative antibiotics did not influence peri-implant crestal bone change or postoperative morbidities compared to preoperative single-dose antibiotics [40]. Additionally, postoperative antibiotics were not superior to a preoperative singledose regimen regarding postoperative infection rates or implant failure in patients undergoing implant surgery, including those with guided bone regeneration but excluding those requiring sinus lift surgery [41]. ...

Reference:

Antibiotic prophylaxis in oral implant surgery in Germany: a cross-sectional study
Do Postoperative Antibiotics Influence One‐year Peri‐implant Crestal Bone Remodeling and Morbidity? A Double‐blinded Randomized Clinical Trial

Clinical Oral Implants Research

... The number of cells in the PDL decreased in orthodontic tooth movement model rats, which may be due to the compression of PDL fibers on the pressure side, leading to capillary embolism and affecting cell metabolism. The invasion of peripheral macrophages into the transparent deformation area promotes its decomposition and absorption, and affects the deposition and absorption of alveolar bone [19,20]. ...

Impact of piezocision-assisted orthodontics on root resorption and alveolar bone: a prospective observational study

... 15,22,28 With growing popularity of adult orthodontics over the past decades, treatment duration becomes a nonnegligible concern of patients. [29][30][31] In general, the average time for orthodontic treatment is currently 2-3 years, but it could be extended due to factors such as inadequate patient cooperation and severity of the malocclusion. 32 Although additional treatments, such as low-level laser therapy and corticotomy have been shown to be beneficial in reducing orthodontic duration, the invasiveness and additional cost of these therapies may also introduce additional perceived risks for patients. ...

Piezocorticision-assisted orthodontics: Efficiency, safety, and long-term evaluation of the inflammatory process
  • Citing Article
  • May 2019

American Journal of Orthodontics and Dentofacial Orthopedics

... This further reinforces the need for early oral hygiene practices and parental education. Studies have shown that visible plaque on the labial surfaces of the maxillary incisors is a significant sign of caries risk in children (Alaluusua & Malmivirta, 1994), and research on adults also revealed that dental caries was positively associated with the severity of periodontal disease, suggesting that high plaque scores and bleeding on probing are correlated with increased risk (Durand et al., 2019;Kallio et al., 1997). ...

Dental caries are positively associated with periodontal disease severity

... (2,15) Integrated oral health models using non-dental professionals have been implemented in other populations with demonstrated effectiveness. (40,41) Employing an oral health coordinator could also facilitate teledentistry consultations to mitigate the need to physically access services. In the literature, palliative care nurses identi ed some limitations with teledentistry, including unreliable internet coverage and the cost of implementation.(15) ...

From theoretical concepts to policies and applied programmes: The landscape of integration of oral health in primary care

BMC Oral Health

... Transcatheter arterial chemoembolization (TACE) is the first-line treatment for primary liver cancer, but postembolization pain is a common accompanying symptom [1]. Pain is an unpleasant emotional experience [2]. Studies have shown that the incidence of moderate to severe pain in patients with primary liver cancer after TACE is 59.3 to 85.5% [3][4][5]. ...

Pain and quality of life in patients undergoing guided piezocorticision- assisted orthodontic treatment
  • Citing Article
  • December 2017

Journal of clinical orthodontics: JCO

... 76,77 The results of the present review underscore the importance of including oral health providers in multidisciplinary healthcare teams as part of health programs that focus on individuals in situations of social vulnerability. 44,78 The major limitation of the current study is the low number of primary studies included in the qualitative and quantitative syntheses. To conduct an analysis of the global burden of dental caries on individuals experiencing food insecurity, a larger number of studies from diverse regions and different countries would be needed. ...

Integration of oral health into primary care: A scoping review protocol

BMJ Open

... The microbes have been linked with colorectal cancer. 57 Fusobacteria gather massively in adenomas -a benign bowel growth that will become cancerous as time goes on. The polymicrobial nature of oral biofilms and the asaccharolytic metabolism of many of these species helps them live well in the microenvironment of colonic lesions. ...

[Association between oral conditions and colorectal cancer: A literature review and synthesis]
  • Citing Article
  • February 2016

Revue d Épidémiologie et de Santé Publique

... For the studies examining chemotherapeutic agents or materials, 16 used various materials in a nursing home setting to lower plaque and microbial counts. Some preventive materials used in these 16 studies included lactoferrin and lactoperoxidase-containing foods; gel and mouth-rinse; moisturizing gel and mouthwash [65][66][67]; chlorhexidine (CHX)/xylitol chewing gum [32,68], CHX spray [33], CHX swabs [34], probiotic lozenges [69], stannous fluoride-based toothpaste [26], and alcohol-free mouth rinses; and gels [35,[70][71][72][73]. A hospital wardbased study explored the use of CHX mouth rinse among older patients [36], and a community-based study investigated the effect of inorganic pyrophosphate as a treatment for older adults with periodontitis [74]. ...

Effectiveness of an alcohol-free essential oil-containing mouthwash in institutionalised elders receiving long-term care: A feasibility study
  • Citing Article
  • March 2014

Gerodontology

... There is an article that reports us about the first case of two late stage complications, epithelial cell discharge, and subsequent epidermal inclusion cyst (EIC) formation during the subepithelial connective tissue grafting (SCTG) and there is also a case which presents a hitherto unreported early complication of SCTG, namely the development of a gingival cyst. This report highlights epithelial cell discharge and EIC formation as a rare yet possible SCTG complications [8,11,17,29,30]. ...

Managing Postoperative Pain Following Periodontal Surgery
  • Citing Article
  • July 2013

Journal (Canadian Dental Association)