Reinhold Ganz’s research while affiliated with University of Bern and other places

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Publications (250)


Extended Retinacular Flap
  • Chapter

February 2025

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12 Reads

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Michael Leunig

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Reinhold Ganz

The extended retinacular flap is a subsequent development of the surgical hip dislocation approach. It is based on a technique of Dunn, proposed 60 years ago, for open reduction of severe slips. The extension, as described in this chapter, further reduces the risk of avascular necrosis of the femoral head and is the condition for several new intraarticular procedures. The chapter describes indications, surgical steps, and technical risks in detail.


Capsular Arthroplasty (Modified Codivilla-Colonna)

February 2025

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11 Reads

Capsular arthroplasty of the hip was abandoned for decades until better understanding of the vascular supply to the hip region and consequent intracapsular procedures allowed reconsideration. Safe surgical hip dislocation (SHD), observance of the capsular blood supply, and dissection of the retinacular flap guaranteed optimal quality of the capsular coverage. Shelf acetabular augmentation, relative lengthening of the neck, reduction of femoral head size, as well as femoral shortening and derotation increased the spectrum of indications and helped increase the pelvi-femoral clearance and avoid femoral head necrosis and stiffness. The capsular arthroplasty is a procedure used to treat congenital hip dislocation by wrapping the capsule around the femoral head and relocating it into a newly reamed anatomically located acetabulum. By interposing capsule, like in the Chiari and shelf procedures, load transmission induces metaplasia of the interposed capsular tissue to fibrous cartilage. When properly selected and executed, such hips can last for decades, function well, and facilitate a routine total hip replacement at an appropriate age. Subsequent to the original technique description, the decreasing prevalence of severe developmental dysplasia of the hip (DDH), in addition to historically high rate of complications like stiffness, necrosis, and the need for early revision, led to the near abandonment of the Colonna following the introduction of total hip arthroplasty (THA). This chapter describes indications, surgical technique, and complications and concludes with a summary of results.


Femoral Neck Osteotomy

February 2025

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10 Reads

The indication for upper intertrochanteric (ITO) and subtrochanteric (STO) femoral osteotomies is becoming less frequent due to the favourable results of total hip replacements even when implanted in rather young adults. In contrast to total hip arthroplasty (THA), the outcome of hip osteotomies can be unpredictable, especially when performed for established osteoarthritis. In addition to this, classic hip osteotomies are burdened with undesired side effects including limb shortening, abductor weakness, extra-articular impingement, local pain from hardware, and more complicated conversion to THA. Using the rather safe surgical hip dislocation (SHD) and the extended retinacular flap technique, the femoral neck area can be approached without interfering with the femoral head perfusion. The osteotomy level can be moved closer to the joint, avoiding or minimizing most side effects of intertrochanteric or subtrochanteric osteotomies. Current indications to perform a femoral neck osteotomy (FNO) include severe valgus deformities, deformities resulting from slipped capital femur epiphysis (SCFE), irregularities of the head contour and post-traumatic deformities. In some complex morphologies, it can be combined with a periacetabular osteotomy (PAO). True femoral neck osteotomy (FNO) is the surgical technique that enables intra-articular corrections at the level of the femoral neck. It can be performed using the surgical hip dislocation and the extended retinacular techniques (see Chaps. 7 and 8). It allows for a larger correction when compared to more distal osteotomies (see Chap. 15) as the osteotomy line lies closer to the femoral head. In addition, adverse side correction effects such as limb shortening and secondary deformity affecting total hip arthroplasty are minimal. The extraordinary good results are faced with a demanding technique. The risk of complications such as avascular necrosis or delayed union is linked to inadequate indication, poor detailed knowledge of the vascular anatomy, imprecise surgical technique, and lack of experience.


Intra-Capital Osteotomy

February 2025

Severe deformities of femoral head and acetabulum after Perthes disease or Perthes-like deformities are prone to early degeneration. Surgical procedures with extracapsular approach can hardly change this prognosis. Application of detailed vascular knowledge has enabled an extension of intracapsular surgery including segmental resection of the femoral head, allowing direct correction of the deformity. This chapter describes indications, technical execution, as well as possible risk factors and complications of the procedure. Finally, it gives an overview of results. The femoral head has an asymmetric dual blood supply, coming primarily from the deep branch of the medial femoral circumflex artery (MFCA) and from the medial branch of the MFCA, each vessel running in a retinacular fold, which can be mobilized from the neck bone. While the supply from the deep branch can perfuse the entire epiphysis, the medial branch perfuses approximately the medial half of the head. Based on this blood distribution, a portion of the central head can be resected without circulatory consequences for both remaining parts. Because the medial portion rests connected with the neck, this retinacular flap does not need to be mobilized. The lateral portion of the head/neck is mobilized after preparation of the lateral flap and becomes reduced against the stable medial portion and fixed with 2(−3) screws. The resected portion can be a parallel segment, or an anterior- or posterior-based wedge. The mobile lateral portion can be rotated, abducted or adducted, and/or shifted in a cephalad or caudad direction, all within the limits of the retinacular tension. Ideally, the “new” head is close to spherical and has the size of the opposite head.


FEMORAL HEAD REDUCTION OSTEOTOMY APPROACH FOR SEVERE PROXIMAL FEMUR DEFORMITIES: SURGICAL TECHNIQUE AND MINIMUM TWO-YEAR RESULTS

August 2024

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16 Reads

Orthopaedic Proceedings

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I. Mafra

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R. Viegas

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[...]

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R. Ganz

Executing an extended retinacular flap containing the blood supply for the femoral head, reduction osteotomy (FHO) can be performed, increasing the potential of correction of complex hip morphologies. The aim of this study was to analyse the safety of the procedure and report the clinical and radiographic results in skeletally mature patients with a minimum follow up of two years. Twelve symptomatic patients (12 hips) with a mean age of 17 years underwent FHO using surgical hip dislocation and an extended soft tissue flap. Radiographs and magnetic resonance imaging producing radial cuts (MRI) were obtained before surgery and radiographs after surgery to evaluate articular congruency, cartilage damage and morphologic parameters. Clinical functional evaluation was done using the Non-Arthritic Hip Score (NAHS), the Hip Outcome Score (HOS), and the modified Harris Hip Score (mHHS). After surgery, at the latest follow-up no symptomatic avascular necrosis was observed and all osteotomies healed without complications. Femoral head size index improved from 120 ± 10% to 100 ± 10% (p<0,05). Femoral head sphericity index improved from 71 ± 10% before surgery to 91 ± 7% after surgery (p<0,05). Femoral head extrusion index improved from 37 ± 17% to 5 ± 6% (p< 0,05). Twenty five percent of patients had an intact Shenton line before surgery. After surgery this percentage was 75% (p<0,05). The NAHS score improved from a mean of 41 ± 18 to 69 ± 9 points after surgery (p< 0,05). The HOS score improve from 56 ± 24 to 83 ± 17 points after surgery (p< 0,05) and the mHHS score improved from 46 ± 15 before surgery to 76 ± 13 points after surgery (p< 0,05). In this series, femoral head osteotomy could be considered as safe procedure with considerable potential to correct hip deformities and improve patients reported outcome measures (PROMS). Level of evidence - Level IV, therapeutic study Keywords - Femoral head osteotomy, Perthes disease, acetabular dysplasia, coxa plana




Bernese periacetabular osteotomy (PAO): from its local inception to its worldwide adoption
  • Literature Review
  • Full-text available

November 2023

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133 Reads

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9 Citations

Journal of Orthopaedics and Traumatology

The development of the Bernese periacetabular osteotomy (PAO) is based on a structured approach starting with an analysis of the preexisting procedures to improve the coverage of the femoral head and was followed by a list of additional goals and improvements. Cadaveric dissections with a detailed description of the vascular supply of acetabulum and periacetabular bone set the stage for an intrapelvic approach, which offered the largest acetabular correction possible combined with safe intracapsular access. The final composition of osteotomies required the development of several instruments and cutting devices before the feasibility could be tested on a series of cadaveric hips. While the sequence of the osteotomies remained largely unchanged over time (except for the pubic and ischial osteotomies), several propositions for an easier/less invasive approach have been discussed; some made it into standard practice. Efforts were undertaken to optimize the learning curve and minimize failures using video-clips, hands-on courses, fellowships, publications, and ongoing mentoring programs. In retrospect, with almost 40 years of experience, such efforts have promoted a worldwide adoption of the Bernese periacetabular osteotomy.

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Fig. 1. The modified capsular arthroplasty in a 13-year-old female patient with DDLH (iHot 62.3, WOMAC 9 and mHHS 74). (A) Pre-operative anterior-posterior radiograph shows the Hartofilakidis Type III dislocation of the hip. (B) Pre-operative MRI shows the good quality of capsular. The outermost superior-lateral capsular thickness is 5.3 mm. (C-H) Intraoperative pictures show the brief steps of the surgery. (C) The femoral head is dislocated and all capsular connections with the acetabular rim are sectioned. (D) and (E) show the measurements of anteroposterior and medial-lateral femoral head diameters. (F) shows the reaming of the acetabular socket. (G) and (H) show the suture of the capsule over the head. X-ray immediately after surgery (I), 2 years post-operatively (J) and 6 years post-operatively (K) (iHot 91.1, WOMAC 5, mHHS 94).
Fig. 1. (Continued)
Fig. 2. The modified capsular arthroplasty combined with proximal femoral derotation and shortening osteotomy in a 20-year-old female with a right hip dislocation (Hartofilakidis Type III). (A) Pre-operative radiograph; (B) post-operative radiograph; (C) 3 years post-operatively and (D) 6 years and 5 months post-operatively. The final radiograph shows the joint space is normal.
The modified capsular arthroplasty for young patients with developmental dislocation of the hip

June 2023

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66 Reads

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2 Citations

Journal of Hip Preservation Surgery

The present study aimed to investigate the clinical results of the modified Codivilla–Hey Groves–Colonna capsular arthroplasty in the treatment of young patients with developmental dislocation of the hip. We retrospectively evaluated 90 patients (92 hips) who underwent the modified capsular arthroplasty from June 2012 to June 2021. Hips were evaluated using the modified hip Harris score (mHHS), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and the 12-item International Hip Outcome Tool (iHOT-12). The Tönnis osteoarthritis grade and the Severin classification system were used to assess the radiographic outcomes. The average age was 15.7 years (range: 8–26 years). The mean pre-operative mHHS, the WOMAC score and the iHOT-12 score were 83.03, 14.05 and 52.79, respectively. The patients were followed for a mean of 41.1 months (range: 12.1–120.9 months). The patients had a mean mHHS of 83.61 (range: 31.2–97), a WOMAC score of 16.41 (range: 0–51) and an iHOT-12 score of 64.81 (range: 12.9–98.2) at the final follow-up. Capsular thickness had a positive predication on the final functional outcomes. The excellent/good rate of radiological reduction was 79.3%. More than 60% of patients had no/slight osteoarthritis. A total of 54 hips (58.7%) had superior radiographic outcomes. The risk factors for inferior radiographic outcomes were capsular quality (odds ratio [OR]: 0.358, 95% confidence interval [CI]: 0.113–0.931) and capsular thickness (OR: 0.265, 95% CI: 0.134–0.525). Joint stiffness was the most common complication (14.1%). We confirmed the efficacy of this procedure in the treatment of developmental hip dislocation. Patients with poor capsular quality are not suitable for this procedure. With suitable selection according to indications, this procedure can restore the hip rotation center with a low incidence of femoral head necrosis or severe osteoarthritis.


Avascular femoral head necrosis in young gymnasts: a pursuit of aetiology and management

September 2022

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285 Reads

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3 Citations

Bone & Joint Open

Aims: Avascular femoral head necrosis in the context of gymnastics is a rare but serious complication, appearing similar to Perthes' disease but occurring later during adolescence. Based on 3D CT animations, we propose repetitive impact between the main supplying vessels on the posterolateral femoral neck and the posterior acetabular wall in hyperextension and external rotation as a possible cause of direct vascular damage, and subsequent femoral head necrosis in three adolescent female gymnasts we are reporting on. Methods: Outcome of hip-preserving head reduction osteotomy combined with periacetabular osteotomy was good in one and moderate in the other up to three years after surgery; based on the pronounced hip destruction, the third received initially a total hip arthroplasty. Results: The described pathology is quite devastating, and extensive joint preserving surgery (which has been shown successful in Perthes' cases) was less successful in this patient cohort. Conclusion: Supraselective angiography may be helpful to improve pathomechanical understanding and surgical decision making.Cite this article: Bone Jt Open 2022;3(9):666-673.


Citations (54)


... Moreover, LT tears can be associated with other hip pathologies such as femoroacetabular impingement (FAI), osteoarthritis, synovial enchondromatosis, osteonecrosis of the femoral head, and hip dysplasia [9,11,15,[18][19][20][21][22][23][24][25]. Diagnosis of LT injury is difficult because imaging and physical examination are nonspecific, and differential diagnosis with other hip pathologies is often difficult [26,27]; magnetic resonance imaging demonstrated a sensitivity and specificity of 50% and 34%, respectively, in identifying any pathological process of the LT [2,20,28,29]. Clinically, a complete hip gait, range of motion, and stability evaluation are required [2]. ...

Reference:

The ligamentum teres and its role in hip arthroscopy for femoroacetabular impingement: a systematic review Journal of Orthopaedics and Traumatology
Bernese periacetabular osteotomy (PAO): from its local inception to its worldwide adoption

Journal of Orthopaedics and Traumatology

... Остеонекроз головки бедренной кости у подростков, профессионально занимающихся спортом, относительно редкое, но тяжелое и быстро прогрессирующее дегенеративно-дистрофическое заболевание. Как синонимы сходных патологических состояний в мировой научной литературе встречаются термины «ишемический», «бессосудистый», «аваскулярный» некроз, а также «костный инфаркт», но в последние годы чаще применяют общий термин «остеонекроз головки бедренной кости» [12][13][14]. ...

Avascular femoral head necrosis in young gymnasts: a pursuit of aetiology and management

Bone & Joint Open

... Pero el tratamiento quirúrgico estándar para mayores de 40 años y con evidencia de osteoartritis es el reemplazo total de cadera. (4)(5)(6)(7)(8) En un intento de recuperar el apoyo de la pared acetabular medial y por tanto del centro de rotación de la cabeza femoral, hay un consenso para el uso de injerto óseo autólogo u homólogo, siendo la cabeza femoral el de preferencia. (9) CASO CLÍNICO Se trata de un paciente de 40 años, masculino, manejado por reumatología por una artritis reumatoide de más o menos 7 años de evolución, pero que desde hace aproximadamente 1 año refi ere dolor persistente en la región de cadera izquierda, cojera en la deambulación por el acortamiento de 2.5 cm, razón por la cual acude desde el interior del país. ...

Acetabular Protrusion and Surgical Technique
  • Citing Chapter
  • August 2022

... [1][2][3] Despite the DAA following an inter-muscular and inter-nervous anatomical interval, most surgeons routinely ligate the ascending branch of the lateral circumflex femoral artery (a-LFCA) for better exposure and to avoid accidental rupturing of the vessels. However, according to a cadaveric study by Kalhor et al, 4 the a-LFCA might be the principal vascular supply to the tensor fascia latae (TFL). Besides the TFL, a consistent contribution to the vascular supply of the gluteus medius and minimus muscles by the a-LFCA has also been identified. ...

Lateral femoral circumflex artery contribution to the articular and periarticular hip circulation: relevance to the anterior hip approach—a cadaveric study

European Journal of Orthopaedic Surgery & Traumatology

... Through defined osteotomies the acetabulum is liberated from the pelvis and after three-dimensional reorientation is fixed in place, thus improving femoral head coverage. Since the first description of the technique by Ganz et al. [1,2], different fixation techniques of the acetabular fragment have been described [3][4][5]. Predominantly, towards the end of the procedure after acetabular reorientation, the intermediate fixation with K-wires is dissolved and a definitive fixation is achieved with screws [1,6]. ...

Surgical Technique: Periacetabular Osteotomy
  • Citing Chapter
  • January 2021

... The probabilistic model is able to generate anatomically relevant variations for the missing bone. The model was tested in real cases and its reconstructions were clinically adopted.Ackerman et al.58 proposed using deep reinforcement learning for automatic surgery planning of femoral osteotomies, utilizing simulated training data tailored to orthopedic interventions based on real patient data. The inference was made on existing cases. ...

A New Approach to Orthopedic Surgery Planning Using Deep Reinforcement Learning and Simulation
  • Citing Chapter
  • September 2021

Lecture Notes in Computer Science

... You will also read about a devastating complication, never clearly explained in literature, after what is considered today the limit of our open conservative surgery. A femoral head reduction osteotomy [4]. Simultaneously, bilateral reconstructive hip surgery utilized in two separate emblematic cases [5,6]. ...

Femoral head necrosis and progressive osteoarthritis of a healed intracapital osteotomy in a severe sequelae of Legg–Calvé–Perthes disease with aplasia of tensor fasciae latae

Journal of Hip Preservation Surgery

... Similarly, it is evident the postoperative results after hip arthroscopy of patients suffering from BHD are influenced by various hip morphology [18,19]. Therefore, PAO could represent the preferable treatment modality for BHD independent of the individual acetabular configuration because PAO enables the correction of the osseous acetabular deformity using a minimally invasive approach in line with fast patient rehabilitation [20,21]. Detailed analysis of PAO outcomes across variable types of acetabular and hip joint configurations in BDH are essential to further improve patient care. ...

Surgical Anatomy of the Rectus-Sparing Approach for Periacetabular Osteotomy: A Cadaveric Study

JBJS Essential Surgical Techniques

... The application of computer-assisted surgery (CAS) to orthopedic surgery has been remarkable in recent years, and many papers have demonstrated its effectiveness in acetabular osteotomy [31][32][33]. It has also been reported on the femoral side, although in smaller numbers [34][35][36]. Takao et al. describe precise proximal femoral osteotomies using CT-based navigation, with angular osteotomy error within 5° and position error within 4 mm [34]. In a systematic review of osteotomies for developmental dysplasia of the hip, Liu et al. found that navigation-assisted techniques in pediatric hip osteotomies enhance surgical precision, reduce operation times, and minimize radiation exposure, thereby improving overall surgical outcomes, suggesting that clinical outcomes of hip osteotomies can be improved through 3D navigation [37]. ...

Computer-assisted femoral head reduction osteotomies: an approach for anatomic reconstruction of severely deformed Legg-Calvé-Perthes hips. A pilot study of six patients

... Specifically, abnormal articular burden and increased pressure caused by FAI resulted in the development of labral tears, cartilage delamination, and eventual secondary oseoarthritis 16,21 . The term FAI was firstly coined and developed by the Ganz group 15,22 ; subsequently an exponential rise of publications about FAI further extended its recognition 23 . ...

Infographic: The history of femoroacetabular impingement

Bone and Joint Research