Raphaëlle Merlo’s research while affiliated with Université Laval and other places

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Publications (7)


A qualitative study of clinicians' impressions regarding the implementation of a clinical and research data collection system
  • Article

July 2024

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39 Reads

Counselling and Psychotherapy Research

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Raphaëlle Merlo

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[...]

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Catherine‐Marie Vanasse

Background Systematically collecting data on clientele databases allows for describing the clientele's needs and addressing various clinical research questions. Conducted in a university psychology clinic, this initiative seeks to improve the overall quality of care provided by integrating evidence‐based practices. This study works to bridge the gap between clinical practice and research. Aims This study aimed to describe the potential repercussions and clinicians' impressions regarding the implementation of this procedure. Research Design An inductive qualitative approach, inspired by Husserl's descriptive phenomenology, was used. To be consistent with this approach, data analysis followed Giorgi's five‐step scientific phenomenological method. Data Collection and Analysis Semi‐structured individual interviews were conducted with 14 volunteer clinicians using an interview guide. The data were analysed to extract central themes using Giorgi's method, which involves collecting verbal data, reading the data, dividing it into units of meaning, organising the data using the language of the discipline and synthesising the results. Results Five central themes emerged: barriers to implementation, potential impacts on therapy, recommendations to enhance participation, perceived utility and an attitude of openness. Discussion The pilot project provides valuable insights into the feasibility and acceptability of systematic data collection in a clinical setting. Clinician consultation proves to be essential in the implementation process, highlighting the importance of addressing practical and philosophical obstacles. Conclusion Understanding clinicians' experiences can guide future implementations of similar systems and improve clinical practice by supporting the integration of systematic data collection. Enhanced communication and training on the data collection system are suggested.


Approaches to studying emotion using physiological responses to spoken narratives: A scoping review
  • Literature Review
  • Full-text available

July 2024

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75 Reads

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2 Citations

Psychophysiology

Narratives are effective tools for evoking emotions, and physiological measurements provide a means of objectively assessing emotional reactions – making them a potentially powerful pair of tools for studying emotional processes. However, extent research combining emotional narratives and physiological measurement varies widely in design and application, making it challenging to identify previous work, consolidate findings, and design effective experiments. Our scoping review explores the use of auditory emotional narratives and physiological measures in research, examining paradigms, study populations, and represented emotions. Following the PRISMA‐ScR Checklist, we searched five databases for peer‐reviewed experimental studies that used spoken narratives to induce emotion and reported autonomic physiological measures. Among 3466 titles screened and 653 articles reviewed, 110 studies were included. Our exploration revealed a variety of applications and experimental paradigms; emotional narratives paired with physiological measures have been used to study diverse topics and populations, including neurotypical and clinical groups. Although incomparable designs and sometimes contradictory results precluded general recommendations as regards which physiological measures to use when designing new studies, as a whole, the body of work suggests that these tools can be valuable to study emotions. Our review offers an overview of research employing narratives and physiological measures for emotion study, and highlights weaknesses in reporting practices and gaps in our knowledge concerning the robustness and specificity of physiological measures as indices of emotion. We discuss study design considerations and transparent reporting, to facilitate future using emotional narratives and physiological measures in studying emotions.

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Use of Teletherapy for the Treatment of People with Psychotic Disorders During Covid-19 Confinement: Acceptability, Feasibility, and Challenges

October 2023

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44 Reads

Canadian Journal of Community Mental Health

Clinical teams working with clients with psychotic disorders have turned to teletherapy to continue offering services to their clients during the Covid-19 pandemic. However, few studies have focused on the challenges of teletherapy by professionals. We conducted a brief online survey with professionals working with clients with a psychotic disorder across Canada. Qualitative analysis of open-ended questions was conducted. Around 86% of the professionals we surveyed began using teletherapy at the beginning of the pandemic. Most professionals (83%) said that they would keep using teletherapy after the end of the pandemic. Numerous advantages and challenges of teletherapy were also discussed.


The neurophysiology of closed-loop auditory stimulation in sleep: A magnetoencephalography study

September 2023

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89 Reads

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5 Citations

European Journal of Neuroscience

Closed-loop auditory stimulation (CLAS) is a brain modulation technique in which sounds are timed to enhance or disrupt endogenous neurophysiological events. CLAS of slow oscillation up-states in sleep is becoming a popular tool to study and enhance sleep's functions, as it increases slow oscillations, evokes sleep spindles and enhances memory consolidation of certain tasks. However, few studies have examined the specific neurophysiological mechanisms involved in CLAS, in part because of practical limitations to available tools. To evaluate evidence for possible models of how sound stimulation during brain up-states alters brain activity, we simultaneously recorded electro- and magnetoencephalography in human participants who received auditory stimulation across sleep stages. We conducted a series of analyses that test different models of pathways through which CLAS of slow oscillations may affect widespread neural activity that have been suggested in literature, using spatial information, timing and phase relationships in the source-localized magnetoencephalography data. The results suggest that auditory information reaches ventral frontal lobe areas via non-lemniscal pathways. From there, a slow oscillation is created and propagated. We demonstrate that while the state of excitability of tissue in auditory cortex and frontal ventral regions shows some synchrony with the electroencephalography (EEG)-recorded up-states that are commonly used for CLAS, it is the state of ventral frontal regions that is most critical for slow oscillation generation. Our findings advance models of how CLAS leads to enhancement of slow oscillations, sleep spindles and associated cognitive benefits and offer insight into how the effectiveness of brain stimulation techniques can be improved.


Fig. 2. Evoked responses over sleep stages, in EEG (Cz). a) Time series of the auditory evoked responses showing the appearance and evolution of late evoked components (N350, N550, P900) in deeper NREM sleep stages. Coloured lines show means across participants; shaded areas indicate standard error. Grey rectangles indicate time ranges of interest that are used for further analysis. Asterisks denote significant differences between Wake and deeper sleep conditions (Wilcoxon signed-rank test on the means; p < .05). b) Amplitudes of the P200 component show little change across sleep stages. Conversely, amplitudes c) at N350 and d) peak-to-trough differences between P900 and N550 are stronger in deeper NREM sleep stages than in Wake.
Fig. 3. Topographies of a) evoked activity differences between wake and NREM sleep (stages N2 and N3 combined). Red indicates more activity change relative to prestimulus baseline during the auditory-evoked N550-P900 complex in sleep as compared to wake. The evoked N550-P900 complex is specific to sleep and shows widespread activity change in ventral and orbital frontal areas (see also Figure 2b,d for topographies of evoked activity in NREM sleep over time). b) Topography of slow frequency oscillatory activity during N2 & N3 sleep stages (as indexed using FOOOF), for reference.
Fig. 4. Topographies of evoked activity in NREM sleep over time (stages N2 & N3 are combined). Brighter red indicates relatively more activity change relative to pre-stimulus baseline. The EEG time series of evoked responses for Wake and N2&N3 is shown (bottom) for reference. Sleep spindles evoked by sound in sleep. To evaluate differences in how sound evokes sleep spindles across stages of con-422
Fig. 5. Sound-evoked sleep spindles in EEG (Cz). a) The time-frequency plot averaged across all subjects (left) shows increased spindle power in N2&N3 sleep 0.6 to 1.2 s after sound onset in a frequency band of 11 to 14 Hz (white rectangle). Spindle power in that frequency range as compared with spindle power in the pre-stimulus baseline (-0.6 to 0 ms) is shown at right. Asterisks denote significant differences between Wake and N2 & N3. b) Spindle activity is positively related to evoked N550-P900 complex amplitude. When epochs are divided according to the strength of the slow oscillation that they produce (i.e., Top vs. Bottom 25%), stronger spindle power is observed to be coincident with stronger N550-P900 complexes in the EEG time-frequency plot (left), and extracted values are higher across subjects (right). Asterisks indicate a significant difference between Wake and deeper sleep conditions (Wilcoxon signed-rank test on the means; p < .05). c) The topography of spindle power differences (in MEG) according to evoked N550-P900 complex strength (Top vs. Bottom 25% of N550-P900 complexes averaged across subjects) shows increased activity in thalamus and frontal midline structures coincident with stronger N550-P900 complexes. d) The topography of spindle power in the 11-17 Hz range across all N2 & N3 sleep epochs, for comparison.
Fig. 6. Evoked responses in N2 & N3. a)Time series, averaged across subjects and hemispheres, for each region of interest. b) Schematic view of regions of interest. c) P200 amplitude differences between Wake and N2 & N3 for each region of interest and each hemisphere. d) N550-P900 complex amplitude differences between Wake and N2 & N3 for each region of interest and each hemisphere. Asterisks denote significant differences between Wake and N2 & N3 (p < .01).
The neurophysiology of closed-loop auditory stimulation in sleep: a MEG study

December 2022

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247 Reads

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1 Citation

Closed-loop auditory stimulation (CLAS) is a brain modulation technique in which sounds are timed to enhance or disrupt endogenous neurophysiological events. CLAS of slow oscillation up-states in sleep is becoming a popular tool to study and potentially enhance sleep's functions, as it can increase slow oscillations, evoke sleep spindles, and enhance memory consolidation of certain tasks. However, few studies have examined the specific neurophysiological mechanisms involved in CLAS, in part because of practical limitations to commonly-used tools. To evaluate evidence for possible models of how sound stimulation during brain up-states might generate slow oscillations, we simultaneously recorded electro- and magnetoencephalography in human participants who received auditory stimulation across sleep stages and neural oscillation phases. The results suggest that auditory information reaches ventral frontal lobe areas via non-lemniscal pathways. From there, a slow oscillation is created and propagated. We demonstrate that while the state of excitability of tissue in auditory cortex and frontal ventral regions shows some synchrony with the EEG-recorded up-states that are commonly used for CLAS, it is the state of ventral frontal regions that is most critical for slow oscillation generation. Our findings advance models of how CLAS leads to enhancement of slow oscillations, sleep spindles, and associated cognitive benefits, and offer insight into how the effectiveness of brain stimulation techniques can be improved.


Study validation of the updated version of the Client Assessment of Strengths, Interests, and Goals

April 2022

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416 Reads

Background: A major model in psychiatry that influences service delivery is the recovery model which emphasizes personal goals and overcoming obstacles to meet them. The Client Assessment of Strengths, Interests, and Goals - CASIG (Wallace, Lecomte, Wilde, & Liberman, 2001) is a well-known functional assessment, that was not only presented deficits and obstacles for psychiatric rehabilitation, but also included short and long-term goals. It included goals, and skills essential to community living, it was used for treatment planning, and repeatedly administered to assess progress over time. Its psychometric properties have been documented within both American and French-Canadian samples. The CASIG has however aged, with items that are not close enough to the recovery model and that reflect treatment paradigms more present in the late 90’s. Hence, this new French version aims to 1) adapt the current version with non-stigmatizing and skills-oriented terms, 2) add new dimensions recognized as important factors for recovery (i.e., sleep, physical exercises), and 3) evaluate its psychometric characteristics: convergent validity, internal consistency, and test-retest reliability. Methods: The self-report was administrated to 201 individuals with serious and persistent mental illness across four French speaking countries (Canada, France, Switzerland and Belgium). The sample included 69.5% females and participants all reported an history of mental disorder: Major depression=90, psychotic disorder=12, eating disorder=3, anxiety disorder=55, bipolar disorder=15, neurodevelopmental disorder=7, and substance use disorder=3. We examined the factor structure, internal consistency, concurrent, and convergent validities of the current version. Instruments for convergent validity were : The Recovery Assessment Scale (Corrigan, Salzer, Ralph, Sangster, & Keck, 2004) , The psychological well-being scale (Ryff & Keyes, 1995), and the World Health Organization disability assessment schedule 2.0 (Ustun et al., 2010). Results: Internal consistency for the resulting subscales ranged from acceptable to good (Kuder Richardson= 0.76 to 0.89). All subscales were significantly, positively associated with established measures of theoretically relevant constructs, demonstrating concurrent and convergent validities. The test-retests also demonstrated stability over times at the two follow-ups: one month, and six months. Discussion: The French CASIG is a reliable and valid instrument assessing individual needs, and the use of those data is structured to determine treatment planning and evaluation, as well as producing aggregate data for research and program purposes. More extensive validity will be presented. These results should be repeated, with an English-speaking sample as well.


Computer Coding for Early Psychosis—An Innovative Pilot Study

February 2021

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48 Reads

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3 Citations

Canadian Journal of Community Mental Health

People with psychotic disorders are at higher risk of not completing an educational degree and tend to get low-wage jobs. We offered computer coding classes to 14 participants. The training was deemed feasible, acceptable, and appeared to increase their motivation for school or work, not only in computer-related domains.

Citations (3)


... However, the relationship between pain experience and empathy remains complex and not fully understood. Athletes, who often experience transient, high-frequency pain, may have a unique capacity to empathize with their teammates' injuries (Savard et al., 2024). Meta-analytical research on pain empathy has revealed variability in neurophysiological responses to pain stimuli. ...

Reference:

Investigating pain empathy in athletes: a quantitative descriptive approach with ERPs
Approaches to studying emotion using physiological responses to spoken narratives: A scoping review

Psychophysiology

... This technique is called closed-loop auditory stimulation, or CLAS (for recent reviews, see (29,30)). Evidence suggests this phenomenon is likely to be mediated through the activation of nonlemniscal ascending auditory pathways, which project broadly to association areas including frontal regions (along with secondary auditory areas), likely also involving the ascending reticular activating system (31,32). Measuring the ability of CLAS to generate additional SOs and spindles therefore offers the prospect of assessing how this pathway functions in the presence of sleep spindles, in addition to measuring auditory-modality-specific evoked responses. ...

The neurophysiology of closed-loop auditory stimulation in sleep: A magnetoencephalography study
  • Citing Article
  • September 2023

European Journal of Neuroscience

... When teaching people with mental disabilities, a mentoring system and constant support of the student devised by V. Koushik were used [27]. The tasks in web services are used to adapt a student with mental disabilities to learning CT and passing the test, these strategies for teaching informatics are used when adapting the training program [25], [27], and in the preliminary preparation of students for the learning process, in the form of speech and cognitive therapy [31], [3], [18]. ...

Computer Coding for Early Psychosis—An Innovative Pilot Study
  • Citing Article
  • February 2021

Canadian Journal of Community Mental Health