Ramy Saad's research while affiliated with University of Surrey and other places

Publications (4)

Article
Full-text available
Selenium is a trace element essential to human health largely because of its incorporation into selenoproteins that have a wide range of protective functions. Selenium has an ongoing history of reducing the incidence and severity of various viral infections; for example, a German study found selenium status to be significantly higher in serum sampl...
Article
Full-text available
Selenium status is an established factor in the incidence, outcome or virulence of various RNA viral infections. Because China has geographic regions that range from extremely high to extremely low selenium intakes, we hypothesized that selenium status might influence the outcome of COVID-19 in these areas. For our analysis, we used reported cumula...

Citations

... Selenium deficiency is very prevalent in severely extremely sick individuals [49,50]. Low selenium status is also more common among patients with COVID-19 with severe illness [47,51]. Supplementation with selenium improves immunological function and reduces oxidative stress, inflammation, and virus pathogenicity [52][53][54]. ...
... The clinical trials of iron chelation therapy for COVID- 19 are ongoing (NCT04333550, NCT04361032, NCT04389801). Intriguingly, the available data suggested that the selenium level is positively associated with clinical complications and outcomes, 253,254 which supports selenium supplementation in COVID-19 patients. 255 Selenium was reported to induce GPX4 expression to protect cells from ferroptosis in the model of stroke 256 and further applied for COVID-19 (NCT04869579, NCT04798677, NCT04751669, NCT04323228). ...