Rama Kumari Badyal's research while affiliated with Postgraduate Institute of Medical Education and Research and other places
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Publications (10)
Cation exchange high performance liquid chromatography (HPLC) is commonly utilized as the first method of screening for thalassemias and hemoglobinopathies worldwide. This method of diagnosis requires knowledge of the clinical background and complete blood counts as well as skill and experience in interpreting the sometimes complex results produced...
Hodgkin lymphomas are malignant hemato-lymphoid neoplasms involving lymph nodes and extra-nodal sites. Bone marrow infiltration at diagnosis is uncommon, occurring in approximately 10 % cases. Such infiltration, when present, is usually focal and often associated with extensive disease, systemic symptoms, cytopenias and unfavorable histology. In th...
Abstract An association between severe aplastic anemia and other autoimmune diseases is rare and has been described in adults for eosinophilic fasciitis, thymomas, systemic lupus erythematosus and thyroid disorders. Herein we report a case of celiac disease on gluten free diet, who presented with progressive pallor, fever and weakness of 1 month du...
Mucous gland adenoma of the lung is an uncommon benign tumor that histologically resembles the mucus-secreting component of tracheobronchial gland. The majority arises within the main, lobar, or segmental bronchi but parenchymal involvement had also been reported. We herein present a case of mucous gland adenoma arising from the left lower lobe bro...
Amongst the lung tumors, granular cell tumor (GCT), also known as granular cell myoblastoma, or Abrikossoff is one of the rarest tumors. Herein, we present a case of a 6-year-old male child who presented with a history of cough, fever and recurrent pneumonia due to a 8 × 5 × 3 cm GCT.
Perforated necrotising amoebic colitis associated with intestinal histoplasmosis has rarely been reported in an immunocompetent individual. Radiology and preoperative features are non-specific and requires histopathological examination for a definitive diagnosis. Hence, this condition needs to be considered in the differential diagnosis of complica...
Animal models of copper toxicosis rarely exhibit neurological impairments and increased brain copper accumulation impeding the development of novel therapeutic approaches to treat neurodegenerative diseases having high brain Cu content. The aim of this study was to investigate the effects of intraperitoneally injected copper lactate (0.15 mg Cu/100...
Citations
... Her 60year-old mother's HPLC showed 46.2% Hb A and peaks in the D-window (25.2%), C-window (6.9%) and an unknown peak [1] and also previously encountered by us [2], indicated double heterozygosity for Hb D-Punjab (HBB: c.364G>C) and Hb Q-India with the C-window peak representing the a Q-India /b D-Punjab hybrid. This was corroborated when her sister showed typical b-thalassemia (b-thal) trait (Hb A 2 4.8%) and her brother showed classical findings for Hb Q-India trait (slim unknown peak with a RT 4.66 min., with a split Hb A 2 peak, a tiny S-window peak and a minuscule Q2 peak just after the Hb Q-India peak) [ Figure 1(D)] [3]. ...
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... In front of lymph node or vertebral involvement suggestive of TB, when the anatomopathological examination shows only a granulomatous lesion without caseous necrosis and negative acid-fast staining, the clinician should evoke a diagnosis of lymphoma. A study reported the case of a 30year-old man, a chronic smoker who was initially treated for a presumptive impression of TB for 6 months without improvement [8]. At the initial diagnosis, there was hilar lymphadenopathy and a few very small (<0.5 cm) abdominal and axillary lymph nodes. ...
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... Couraud et al. [3] reported a case of a 54-year-old male patient with symptoms of bronchial obstruction following acute pneumonia. Badyal et al. [5] recently reported bronchial mucous gland adenoma in the left lower lobe of lung in a 32-year-old female misdiagnosed as tuberculosis for two years. ...
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... Anemia is the most common hematological abnormality of CD. In addition to the different etiologies of CD anemia (iron deficiency in consequence of micronutrient deficiency or chronic disorders), several cases of CD-related aplastic anemia have been depicted in the literature (84)(85)(86)(87)(88)(89), both in pediatric and adult age groups. Although the underlying cause of this association is still unknown (84), it has been proposed that both conditions, mediated by autoreactive T cells involved in tissue destruction, may share a similar underlying pathophysiological mechanism (85). ...
... Les formes pédiatriques de TCG trachéobronchiques restent exceptionnelles, intéressant essentiellement la muqueuse trachéale, (103,104) avec un retentissement fonctionnel parfois marqué et une prise en charge souvent invasive (ex : pneumonectomie gauche pour volumineuse TCG bénigne lobaire supérieure gauche de 8cm chez un garçon de 6 ans). (105) Un seul cas pédiatrique était rapporté dans notre travail, chez une enfant de 13 ans, atteinte d'une volumineuse lésion trachéale infiltrante traitée chirurgicalement par résection-anastomose de trachée. ...
... According to the literature, only nine DH cases in the digestive tract of immunocompetent patients have been reported, among which none of the cases reported concomitant involvement of esophagus and colon (see Table 1) [2,[5][6][7][8][9]. This is a rare and typical DH case encroaching on esophagus, colon, liver, spleen and bone marrow in an immunocompetent individual. ...
... Histological examination proved these detrimental effects of copper on the liver and brain cells of the rats. There was significant degeneration in both the hepatocytes and neurons that correspond to the phenotypic manifestations of copper toxicity [12,50]. The toxicity observed in histological examination was attributed to the ROS and oxidative stress that may have triggered apoptosis [42]. ...
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