R. Del Buono’s research while affiliated with Campus Bio-Medico University and other places

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Publications (2)

The intestinal permeability syndrome, celiac disease, gluten sensitivity, autistic spectrum, mycotoxins and immunological tolerance
  • Article
  • Full-text available

August 2013

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547 Reads

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2 Citations

Mediterranean Journal of Nutrition and Metabolism

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C. Di Rienzo

The onset of several human diseases takes place in an inefficient intestine. We probably should re-evaluate the relationship between food and health. Three million Italians and twenty million Americans suffer from the gluten sensitivity syndrome, similar yet different from celiac disease. Different pathological status arise as a consequence of sensitivity to gluten, depending on the genetic polymorphism of the subjects and the environment in which they live. If we gain more knowledge on interactions between food, eating habits, genomics and the environment, this could mean better prevention and/or treatment. The era of epigenetics has begun, while the dogma of genetic determinism seems to be fading.

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Citations (2)

... Since these diseases are connected to genetic factors, there are no effective medical treatments to cure these diseases. Hence, a gluten-free diet is a must for these patients [58,59,64,92,114]. In 2017, the gluten-free pasta market valued $909.8 million globally and is projected to reach $1,289.2 million by 2025 For these reasons, there are numerous research projects to develop gluten-free pasta. ...

Reference:

Corresponding authors: Essam Review: Gluten Related Disorders and Novel Approaches in Gluten-Free Pasta Making
The intestinal permeability syndrome, celiac disease, gluten sensitivity, autistic spectrum, mycotoxins and immunological tolerance
  • Citing Article

  • April 2013

Mediterranean Journal of Nutrition and Metabolism

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C. Di Rienzo

... Mycotoxin-producing molds have lately been found to infect the intestinal tract to cause leaky gut, thus exerting important immunosuppressive activity, and produce neurotoxins (168). OTA, that has nephrotoxic, hepatotoxic, immunotoxic, and genotoxic effect and induces carcinogenicity, teratogenicity, and mutagenicity, has also been seen to cause dysregulation of several gene expression including the upregulation of SOX9 (169), i.e., a gene involved in the development of the male phenotype and has been detected in autistic cases (170). ...

Reference:

Engaging One Health for Non-Communicable Diseases in Africa: Perspective for Mycotoxins
The intestinal permeability syndrome, celiac disease, gluten sensitivity, autistic spectrum, mycotoxins and immunological tolerance

Mediterranean Journal of Nutrition and Metabolism

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C. Di Rienzo