Priya Nimbalkar’s research while affiliated with San Jose State University and other places

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Publications (1)


Figure 1. Schematic representation of (a) MIVM device, (b) doxorubicin-loaded LPHNPs, (c) 2D cell culture, and (d) 3D cell cultures.
Figure 3. Untreated HeLa cells (a) with and (b) without DAPI stain; (c) cytotoxic analysis of 2D culture cells by the MTS assay; HeLa cells treated with NPs (d) with and (e) without DAPI stain; (f) cell viability in 2D culture corresponding to doxorubicin concentrations.
Figure 4. (a) HeLa cells encapsulated in sodium alginate bead, phase contrast microscopic images of spheroids after (b) 2 days, (c) 8 days, live/dead cells staining results, (d) control spheroids (spheroids without NPs), (e) and (f) spheroids cultured with doxorubicin-loaded LPHNPs, and (g) cell viability in 3D culture corresponding to doxorubicin concentrations.
Improving the physiological relevance of drug testing for drug-loaded nanoparticles using 3D tumor cell cultures
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July 2019

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2 Citations

MRS Communications

Priya Nimbalkar

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Peter Tabada

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Improving the physiological relevance of drug testing for drug-loaded nanoparticles using 3D tumor cell cultures - Volume 9 Issue 3 - Priya Nimbalkar, Peter Tabada, Anuja Bokare, Jeffrey Chung, Marzieh Mousavi, Melinda Simon, Folarin Erogbogbo

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Citations (1)


... In one study, flash technology was used to produce lipid-coated polymer nanoparticles loaded with the anticancer drug doxorubicin. 87 The nanoparticles were made of PLGA and lecithin/1,2-distear oyl-snglycero-3-phosphoethanolamine (DSPE)-PEG. The mixer was herringbone-patterned, fabricated by 3D printing. ...

Reference:

Scalable Production of Microscopic Particles for Biological Delivery
Improving the physiological relevance of drug testing for drug-loaded nanoparticles using 3D tumor cell cultures

MRS Communications