Pradip Joshi’s scientific contributions

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Publications (3)


FIGURE 1. Hypothesis on how multiple toxic exposures, including multiple vaccines (2), chemical (3), radiological and biological (4) exposures, may have resulted in Gulf War illness in predisposed, susceptible individuals (1) [modified from Nicolson et al. (23)].  
TABLE 1 . Overview of the Potential Causes of Abnormal Fatigue
TABLE 1 . List of Medications Used for Exclusion
TABLE 2 . Demographic Features of Our Sample
TABLE 3 . Monoclonal Antibodies Used for Immunophenotyping

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Myalgic Encephalomyelitis/Chronic Fatigue SyndromeClinical Working Case Definition, Diagnostic and Treatment Protocols
  • Article
  • Full-text available

December 2011

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2,034 Reads

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696 Citations

Journal of Chronic Fatigue Syndrome

Bruce M. Carruthers

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Kenny L. De Meirleir

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Marjorie I. van de Sande

Recent years have brought growing recognition of the need for clinical criteria for myalgic encephalomyelitis (ME), which is also called chronic fatigue syndrome (CFS). An Expert Subcommittee of Health Canada established the Terms of Reference, and selected an Expert Medical Consensus Panel representing treating physicians, teaching faculty and researchers. A Consensus Workshop was held on March 30 to April 1,2001 to culminate the review process and establish consensus for a clinical working case definition, diagnostic protocols and treatment protocols. We present a systematic clinical working case definition that encourages a diagnosis based on characteristic patterns of symptom clusters, which reflect specific areas of pathogenesis. Diagnostic and treatment protocols, and a short overview of research are given to facilitate a comprehensive and integrated approach to this illness. Throughout this paper, “myalgic encephalomyelitis” and “chronic fatigue syndrome” are used interchangeably and this illness is referred to as “ME/CFS.”

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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

January 2003

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320 Reads

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664 Citations

Journal of Chronic Fatigue Syndrome

Recent years have brought growing recognition of the need for clinical criteria for myalgic encephalomyelitis (ME), which is also called chronic fatigue syndrome (CFS). An Expert Subcommittee of Health Canada established the Terms of Reference, and selected an Ex- pert Medical Consensus Panel representing treating physicians, teaching faculty and researchers. A Consensus Workshop was held on March 30 to April 1, 2001 to culminate the review process and establish consensus for a clinical working case definition, diagnostic protocols and treatment protocols. We present a systematic clinical working case definition that


Cette brochure est une traduction autorisée du document intitulé : Myalgic Encephalomyelitis/Chronic Fatigue Syndrome : A Clinical Case Definition and Guidelines for Medical Practitioners - An Overview of the Canadian Consensus Document (2005/2006) Cet Overview est un abrégé du document intitulé : « Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols - A Consensus Document » i

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Citations (2)


... Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), classified by the WHO with the ICD-11 8E49 code as a postviral fatigue syndrome, and fibromyalgia (FM) (ICD-11 MG30.0 for chronic primary pain) (Harrison et al., 2021), are chronic, disabling, acquired diseases, characterized by complex symptomatology that affects multiple organs (Bateman et al., 2021;Wolfe et al., 2010). Diagnosis of ME/CFS and FM continues to be based on the clinical assessment of unspecific symptoms, such as debilitating fatigue, generalized pain, cognitive impairment or intestinal, sleep, and immune disturbances (Carruthers et al., 2011;Carruthers et al., 2003;Wolfe et al., 2016;Wolfe et al., 2010;Wolfe et al., 1990). Their frequent co-diagnosis drove the hypothesis of a single syndrome and promoted the search for common or differentiating factors (Abbi and Natelson, 2013;Natelson, 2019;Wessely et al., 1999). ...

Reference:

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Journal of Chronic Fatigue Syndrome

... All ME/CFS cases were diagnosed by expert physicians according to the 2003 Canadian consensus criteria. 38 Participants in both groups were excluded if they were diabetic, smoked cigarettes, consumed excessive amounts of alcohol, had an orthopaedic limitation preventing them from performing the cardiopulmonary exercise test (CPET), or had any of the following diagnoses: an autoimmune disease, schizophrenia, major depressive disorder, bipolar disorder, or an anxiety disorder. Healthy subjects included in the present study were categorized as "low-active": they had a sedentary job and no regular organized physical activity in the past 6 months. ...

Myalgic Encephalomyelitis/Chronic Fatigue SyndromeClinical Working Case Definition, Diagnostic and Treatment Protocols

Journal of Chronic Fatigue Syndrome