Philippe Acar’s research while affiliated with Université Toulouse III - Paul Sabatier and other places

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (191)


Paediatric 3D transoesophageal echocardiography reveals prolapse of accessory mitral valve tissues into the left atrium in a neonate
  • Article

November 2024

European Heart Journal Cardiovascular Imaging

Ramona Ghenghea

·

Clément Karsenty

·

Philippe Acar

·





3D real-time TOE of the atrial septal device before release in a 17 kg patient with a central atrial septal defect (ASD). (A) The figure demonstrates a 3D en face view of a 22 mm device from both the left atrium (left panel) and the right atrium (right panel) with the wire still attached (red arrows) (Supplementary Video S1). (B) Depiction of the “Minnesota maneuver” showing the pull on the right disk (Supplementary Video S2). 3D: three-dimensional; ASD, atrial septal defect; LA, left atrium; RA, right atrium; TOE, transoesophageal echocardiography.
3D TOE in a 5 kg patient with a ventricular septal defect (VSD). (A) Dual cropping views on 3D real-time of the perimembranous VSD with outlet extension (yellow arrow) from the LV close to the aortic valve (red asterix) (left panel) and from the RV close to the tricuspid valve (black asterix) (Supplementary Video S3). (B) Transillumination rendering in dual cropping views with Flexilight™ highlighting the perimembranous VSD with outlet extension (Supplementary Video S4). 3D, three-dimensional; LV, left ventricle; RV, right ventricle; VSD, ventricular septal defect.
Tri-plane real-time left ventricular (LV) view. Demonstration of normal LV function in a 5 kg patient with a VSD (Supplementary Video S5). The same patient as in Figure 3. VSD: Ventricular septal defect.
3D TOE in a 5.2 kg patient with a complete atrioventricular septal defect (AVSD). (A) Dual cropping views on 3D real-time of the common valve from the atrium (left panel), displaying the five leaflets, and from the ventricle (right panel) (Supplementary Video S6). (B) 3D live view from the lateral aspect of the LV showing both the ostium primum ASD (yellow arrow) and the inlet VSD (red arrow) (Supplementary Video S7). 3D, three-dimensional; AVSD, atrioventricular septal defect; ASD, atrial septal defect; LV, left ventricle; VSD, ventricular septal defect; SBL, superior bridging; RAL, right anterior leaflet; LML, left mural leaflet; IBL, inferior binding leaflet; RPL, right posterior leaflet.
3D colour TOE in a 9.6 kg patient with mitral valve regurgitation. The figure presents a 3D colour live view of severe functional mitral regurgitation without any congenital abnormality of the valve (Supplementary Video S8). 3D, three-dimensional.

+6

Advancing paediatric cardiac imaging: a comprehensive analysis of the feasibility and accuracy of a novel 3D paediatric transoesophageal probe
  • Article
  • Full-text available

December 2023

·

87 Reads

·

3 Citations

Aims Pediatric transoesophageal echocardiography (TOE) probes have remained two-dimensional (2D) limiting their use compared to adults. While critical in pediatrics for interventions and post-surgery assessments, technological advancements introduced a three-dimensional (3D) pediatric TOE probe. This study assessed the new 3D pediatric TOE probe (GE 9VT-D) for feasibility, handling, and imaging quality. Methods and results At Children's Hospital of Toulouse, 2-month prospective study enrolled children undergoing TOE with the new probe. All imaging modalities were rated by 2 operators using a 5-point Likert-type scale from 1 (very poor) to 5 (very good) quality. Forty-five children, median age 3.7 (range: 2 months-14.7 years) median weight 7.8 kg (range: 4.3–48 kg) underwent 60 TOEs: 25% pre-surgery, 45% post-surgery, 28% during percutaneous procedures, and 2% in intensive care. Probe handling was “very easy” in all cases without adverse events. The median score of 2D, 2D colour, pulsed Doppler and 3D were noted 5 out of 5 and continuous Doppler and 3D colour 4 out of 5. The 3D image quality remained consistent irrespective of the patient weighing above or below 7.8 kg (p = 0.72). Postoperative TOEs identified two cases needing further interventions, emphasizing its value in evaluating surgical outcomes and also for guiding percutaneous interventions. Conclusion Our comprehensive evaluation demonstrates that the new 3D pediatric TOE probe is feasible and provides high-quality imaging in pediatric patients. The successful integration of this novel probe into clinical practice has the potential to enhance diagnostic accuracy and procedural planning, ultimately optimizing patient outcomes in pediatric cardiac care.

Download

Impact of 3D-printed models in meetings with parents of children undergoing interventional cardiac catheterisation

January 2023

·

156 Reads

·

5 Citations

Background Paediatric interventional catheterisation has consistently improved in recent decades, with often highly successful outcomes. However, progress is still required in terms of the information delivered to parents and how parental anxiety is managed. Aim To investigate the impact of cardiac printed models on improving parental understanding and alleviating anxiety before interventional catheterisation. Methods The parents of children undergoing interventional cardiac catheterisation were prospectively enrolled in the study. A questionnaire highlighting knowledge and understanding of the condition and cardiac catheterisation per se was scored on a scale of 1–30. The State-Trait Anxiety Inventory (STAI), which generates current anxiety scores, was also used before and after the pre-catheterisation meeting. The “printing group” received an explanation of catheterisation using the device and a three-dimensional (3D) model, while the “control group” received an explanation using only the device and a manual drawing. Results In total, 76 parents of 50 children were randomly assigned to a “control group” ( n = 38) or “printing group” ( n = 38). The groups were comparable at baseline. The level of understanding and knowledge improved after the “control group” and “printing group” meetings (+5.5±0.8 and +10.2±0.8; p < 0.0001 and p < 0.0001, respectively). A greater improvement was documented in the “printing group” compared to the “control group” ( p < 0.0001). The STAI score also improved after the explanation was given to both groups (−1.8±0.6 and −5.6±1.0; p < 0.0001 and p < 0.0001). The greatest improvement was noted in the “printing group” ( p = 0.0025). Most of the parents (35/38 from the “printing group”) found the models to be extremely useful. Conclusion 3D-printed models improve parental knowledge and understanding of paediatric cardiac catheterisation, thereby reducing anxiety levels.






Citations (48)


... Therefore, transition care process to adult care for children with chronic diseases should be considered as a top priority area for health policies (8). As a matter of fact, benefits achieved by a successful transition in various chronic conditions (e.g., diabetes, congenital heart and pulmonary disease, etc.) have been largely documented (9)(10)(11)15), whereas similar evidence for chronic gastrointestinal diseases is still more sparse but promising (5,7). ...

Reference:

Transition process in children with chronic liver diseases: what is the challenging point?
Efficacy of a Transition Program in Adolescents and Young Adults With Congenital Heart Disease: The TRANSITION-CHD Randomized Controlled Trial
  • Citing Article
  • June 2024

Journal of Adolescent Health

... Dr. Sanchis et al. have recently published their experience with this particular probe in a small number of LAA occlusion cases with excellent feedback in terms of patient's tolerance and imaging quality [18]. Dr Karcenty et al. have also published data from the use of this particular probe in a pediatric population, showing superior quality of images compared with other 2D pediatric probes [19]. While previous studies have included procedures using miniaturized TEE probes [15][16][17]20,21], ours is unique by the fact that this is the first commercially available probe boasting full 3D options and capable of supporting all TEE examinations and transcatheter procedures in adults. ...

Advancing paediatric cardiac imaging: a comprehensive analysis of the feasibility and accuracy of a novel 3D paediatric transoesophageal probe

... Thus, a new 3D pediatric TOE probe (GE 9VT) received CE approval. This probe offers all imaging modes (from 2D to 3D) (7,8). However, the successful integration of any new technology into routine clinical practice necessitates evaluation of its feasibility, accuracy, and safety. ...

Experiencia inicial con ecocardiografía transesofágica pediátrica tridimensional
  • Citing Article
  • January 2023

Revista Espa de Cardiologia

... [7][8][9][10] It also serves as a valuable educational resource for both the patients and their parents, which fosters increased confidence and reassurance for everyone involved. 11 This literature suggests that 3D printing is a useful strategy for increasing surgical efficacy, however, previous reviews largely grouped adult and pediatric populations together, 8,9,10,12 or focused on spinal orthopedic surgeries. 13 This review aims to compare specific outcomes (operative time, radiation exposure, and intraoperative blood loss) in pediatric orthopedic upper and lower limb surgeries. ...

Impact of 3D-printed models in meetings with parents of children undergoing interventional cardiac catheterisation

... Thus, a new 3D pediatric TOE probe (GE 9VT) received CE approval. This probe offers all imaging modes (from 2D to 3D) (7,8). However, the successful integration of any new technology into routine clinical practice necessitates evaluation of its feasibility, accuracy, and safety. ...

Such a long wait: Three-dimensional paediatric transoesophageal echocardiography finally arises
  • Citing Article
  • December 2022

Archives of Cardiovascular Diseases

... The principles of "As Low As Reasonably Achievable" (ALARA), "Image Gently", "Step Lightly", and "Pause and Pulse" should be followed [74]. Additional precautions should be implemented, for example minimizing fluoroscopy time, using collimation, lowering the frame rate, holding the last image, and using digital zoom whenever possible [63,75]. Efforts should be made to avoid any unnecessary radiation of the pediatric eye or gonads. ...

Radiation dose during catheter ablation in children using a low fluoroscopy frame rate
  • Citing Article
  • March 2022

Archives of Cardiovascular Diseases

... 4 Ischemic heart disease (IHD) can lead to AF, contributing to chronic coronary syndrome (CCS) or ACS. 5 Approximately 40% of individuals with AF also have CAD, and AF increases the risk of myocardial infarction in both CAD and non-CAD patients. 6 A notable proportion of ACS patients, particularly those undergoing PCI, also present with AF. 7 Patients with combined AF and ACS share common risk factors for developing CAD, making their coexistence frequent. 8 AF complicates around 10% of acute myocardial infarction cases in the postreperfusion era. 9 Despite advancements in treatment, a substantial proportion of AF patients also have CAD. 10 Anticoagulation initiation based on CHA2DS2VASc score is recommended, particularly in valvular AF (Table 1). ...

Cohort profile: the ESC EURObservational Research Programme Atrial Fibrillation III (AF III) Registry
  • Citing Article
  • July 2021

... Hence, performing accurate surgery for more complex CHD will be challenging and the need for patient-specific and super-flexible 3D heart models will continue to increase [42][43][44]. They will be used to transfer skilled surgical techniques to young surgeons [8][9][10][11][12]45,46], as well as catheterization techniques to young pediatricians [47] and anatomical information to medical students [48,49]. Another important application of 3D printing is to help develop new surgical procedures for complex CHD. ...

The usefulness of 3D printed heart models for medical student education in congenital heart disease

... The average surface error, including those of the outer and inner surfaces, between the volumetric data of the CT-scanned final products and those of the original patients after segmentation was 0.58 ± 0.23 mm. Considering that the spatial resolution of cardiac CT in this clinical trial was 0.3-0.5 mm depending on the institution and considering previously published reports using manual measurements and the manual skill of the surgical technique [29][30][31], the error in the super-flexible 3D heart models is likely to be acceptable to surgeons. ...

Feasibility and accuracy of printed models of complex cardiac defects in small infants from cardiac computed tomography

Pediatric Radiology

... Notably, the authors suggest that the cardioembolic origin of the stroke attributable to CHD, in the absence of underlying vasculopathy, potentially increases the odds of successful recanalization. 132 The cases mentioned highlight successful interventions in pediatric patients with CHD-related ischemic stroke, underscoring the potential for effective treatment in such cases and the need for further research and evidence. However, interventions in pediatric patients need technical modifications, because of several limitations. ...

Case Report: Late Successful Thrombectomy for Ischemic Stroke in a 2-Year-Old Child