Patrick Luyten’s research while affiliated with KU Leuven and other places

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Publications (474)


Physical Activity, Sleep and Eating in Young People With Borderline Personality Disorder
  • Article

January 2025

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21 Reads

Personality and Mental Health

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Jordy A. W. Silvius

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Previous research suggests a connection between borderline personality disorder (BPD) and somatic comorbidities, underscoring the importance of lifestyle and health‐related behaviour (LHRB) in the emergence of BPD. We investigated LHRBs—physical activity, sleeping and overeating—among young people at different BPD stages compared to a matched community sample. Furthermore, we explored whether problematic LHRBs intensify in later BPD stages. Participants included 55 young people exhibiting BPD features from a specialized mental health care institution, matched with a community control group based on age, self‐reported and education. A MANOVA assessed differences in physical activity, sleep disturbance, sleep‐related impairment and emotional overeating between the BPD and control group. A second MANOVA explored these behaviours across BPD stages within the clinical group. Results revealed significantly higher levels of sleep‐related problems among young people with BPD features compared to controls. However, no significant differences were found in physical activity or emotional overeating. Furthermore, problematic LHRBs did not show a significant association with BPD stage. These findings contribute to a better understanding of the relationship between BPD and problematic LHRBs, emphasizing the importance of early intervention targeting sleep‐related problems in young people with BPD, alongside addressing other aspects of BPD and associated LHRBs.


Cross-level interaction of prementalizing and daily externalizing difficulties on daily autonomy-supportive parenting in early adolescence
Cross-level interaction of certainty about mental states and daily parenting stress on adolescent-reported daily controlling parenting in early adolescence
Cross-level interaction of certainty about mental states and daily externalizing difficulties on daily autonomy-supportive parenting in early adolescence
Cross-level interaction of interest and curiosity and daily internalizing difficulties on daily controlling parenting in middle adolescence
Cross-level interaction of interest and curiosity and daily externalizing difficulties on daily controlling parenting in middle adolescence
The Role of Parental Reflective Functioning in Associations between Daily Autonomy-Relevant Parenting, Parenting Stress, and Early and Middle Adolescents’ Day-to-Day Difficulties
  • Article
  • Publisher preview available

December 2024

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52 Reads

Journal of Youth and Adolescence

Autonomy-supportive parenting benefits adolescents’ psychosocial adjustment, but daily fluctuations in adolescent difficulties and parenting stress can reduce autonomy support and lead to more controlling practices. However, currently it is not yet well understood why some parents seem better able to deal with the daily upheavals characteristic of adolescence, while other parents may resort to controlling practices. To address this gap, the present studies examined the moderating role of parental reflective functioning (i.e., parents’ capacity to understand their adolescent’s behavior in terms of mental states) in the daily relationships between adolescent difficulties, parental stress, and autonomy-supportive or controlling parenting. Two 7-day diary studies were conducted, of which Study 1 involved 220 parents of early adolescents (Mage = 13.05 years, SD = 0.87, range 10–15, 66% female) and Study 2 involved 161 parents of middle adolescents (Mage = 15.56 years, SD = 1.14, range = 13–18, 61.5% female). Multilevel analyses indicated that daily perceived externalizing difficulties and parental stress were associated with less autonomy-supportive and more controlling parenting. Furthermore, prementalizing (i.e., attributing malevolent intentions to adolescents) predicted less autonomy support and more controlling parenting. Greater interest and curiosity about adolescents’ mental states buffered the associations between middle adolescents’ (internalizing and externalizing) difficulties and parent-reported controlling parenting. These findings highlight the role of both parent and adolescent characteristics in day-to-day parenting fluctuations and underscore the importance of parental reflective functioning in understanding variations in autonomy-supportive and controlling practices.

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Final factor model of the German PRFQ
All items were retained regardless of factor loadings, given that we wanted to retain as much of the original content validity and theory base as possible. Only two items were removed to achieve model fit. Significant estimates are marked with*. Estimates in front of parathesis are unstandardized, estimates inside of parenthesis are standardized. Standard errors are in front of parentheses, error variances inside of parentheses. Unstandardized and standardized estimates for covariances were identical. Figure available at https://osf.io/j69wx/, under a CC-BY 4.0 license.
Participants’ sociodemographic characteristics
Correlational analyses assessing concurrent validity
Parental considerations about their childs’ mental health: Validating the German adaptation of the Parental Reflective Functioning Questionnaire

December 2024

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67 Reads

Introduction Parental Reflective Functioning describes the parents’ ability to view their child as motivated by mental states. The Parental Reflective Functioning Questionnaire (PRFQ) represents an 18-item and three-factor self-report measure. Our goal was to conduct the first German validation study. Method In a community sample of 378 mothers of children aged 10.2–78.6 months, we used Confirmatory Factor Analysis with a cross-validation approach to assess model fit. Reliability was measured using Cronbach’s α and McDonald’s ω. Concurrent validity was assessed using correlations with relevant constructs. Results The three-factor structure of the original validation could be confirmed. The German model only needed minor modifications: two items had to be removed, and one error covariance was added. The resulting 16-item questionnaire with the three subscales “Pre-mentalizing”, “Interest and Curiosity about Mental States”, and “Certainty about Mental States” was successfully cross-validated (CFI = .94, TLI = .93, SRMR = .07, RMSEA = .04 (CI [.01, .06])). These factors were related in theoretically expected ways to parental attachment dimensions, emotional availability, parenting stress, and infant attachment status. Conclusion While reliability could still be improved, the German 16-item version of the PRFQ represents a valid measure of parental reflective functioning.


Schematic model of the mediating role of Credulity (A) and Mistrust (B) on the relationship between childhood trauma as measured by the Childhood Trauma Questionnaire (CTQ), and Truth-discrimination. Controlling for age, gender, education, Cognitive Reflections Task (CRT) and income. Study 1 n = 663 *p < .01 **p < .001.
Schematic model of the mediating role of Credulity (A) and Mistrust (B) on the relationship between childhood trauma as measured by the Maltreatment Abuse and Exposure Scale (MAES), and Truth-discrimination. Controlling for age, gender, education and income. Study 2 n = 443 *p < .01, **p < .001.
A. Correlations between ETMCQ subscales, conspiracy beliefs, score on the CRT and dependent variables [Truth-discrimination, Fake accuracy (False alarm) and Real news accuracy (Hit)] B. Linear multiple regression of ETMCQ subscales on the fake/real measures (n = 475), controlling for sex, education, income, CRT and age, FDR corrected.
Spearman correlations between ETMCQ subscales, conspiracy beliefs, and conspiracy beliefs in relation to COVID-19 controlling for CRT, sex, age, annual income and level of education (FDR corrected)
A. Spearman correlations between ETMCQ subscales and dependent variables [Truth-discrimination, Fake accuracy (False alarm) and Real news accuracy (Hit)] B. Linear multiple regression of ETMCQ subscales on the fake/real measures (n = 472), controlling for sex, education, income and age, FDR corrected.
The role of epistemic trust and epistemic disruption in vaccine hesitancy, conspiracy thinking and the capacity to identify fake news

December 2024

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53 Reads

Epistemic trust ‐ defined as readiness to regard knowledge, communicated by another agent, as significant, relevant to the self, and generalizable to other contexts–has recently been applied to the field of developmental psychopathology as a potential risk factor for psychopathology. The work described here sought to investigate how the vulnerability engendered by disruptions in epistemic trust may not only impact psychological resilience and interpersonal processes but also aspects of more general social functioning. We undertook two studies to examine the role of epistemic trust in determining capacity to recognise fake/real news, and susceptibility to conspiracy thinking–both in general and in relation to COVID-19. Measuring three different epistemic dispositions–trusting, mistrusting and credulous–in two studies (study 1, n = 705; study 2 n = 502), we found that Credulity was associated with inability to discriminate between fake/real news. We also found that both Mistrust and Credulity mediated the relationship between exposure to childhood adversity and difficulty in distinguishing between fake/real news, although the effect sizes were small. Finally, Mistrust and Credulity were associated with general and COVID-19 related conspiracy beliefs and vaccine hesitancy. We discuss the implications of these findings for our understanding of fake news and conspiracy thinking.


Mentalization-Based Treatment for Adolescent Depression

December 2024

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86 Reads

Psychodynamic Psychiatry

Depression is a very common mental health problem in adolescence. Although over the past decades a number of psychological interventions for depression in adolescence have been developed and empirically evaluated, recent systematic reviews and meta-analyses suggest that there is considerable room for improvement of their effectiveness. This is particularly true for the treatment of adolescents with “complex” depression, that is, those where depression is embedded within broader personality and relational problems, often related to a history of attachment trauma. Mentalization-based treatment (MBT) may be particularly effective in these cases, as it has a strong focus on temporary and long-term impairments in mentalizing (i.e., the capacity to understand the self and others in terms of intentional mental states), which are very typical of adolescents with depression. This article outlines a continuum of severity of depression as seen from a mentalizing perspective, ranging from the mild to moderate to the more severe end of the spectrum. This is followed by a summary of the mentalizing approach to understanding depression along the spectrum of severity, the empirical evidence supporting this approach, and a description of the basic principles of MBT for depression. We close with some thoughts about the future of MBT in the treatment of depression in adolescents.


Citations (34)


... Mentalizing encompasses four distinct dimensions: automatic versus controlled, affective versus cognitive, self versus other, and inner versus outer, as elucidated by Fonagy and Luyten (2009). This mentalizing process is intricately tied to our attachment systems, which can become disrupted when emotional responses are triggered in our relationships (Fonagy et al., 2010). In the therapeutic process, the therapist's task is to balance these dimensions while also attending to the young person's attachment system, thereby facilitating the development of a more grounded and empathetic perception of themselves and their social environment. ...

Reference:

Co-Constructing Mentalizing Contexts in Therapeutic Work with Adolescents-Exploring Resilience in Social Support Networks
Chapter 2. Attachment and Personality Pathology
  • Citing Chapter
  • December 2024

... The current spectrum of mentalization-based interventions includes (a) dynamic interpersonal therapy (Lemma et al., 2024), a brief (16-session) manualized treatment for depression that combines a mental process focus and a mental representation focus for patients in the mild-tomoderate range of the spectrum ; (b) dynamic interpersonal therapy for complex care (Rao et al., 2019), which is slightly longer (26 sessions) and has a greater process or mentalizing focus than brief dynamic interpersonal therapy, which makes it more suitable for patients with more severe impairments in mentalizing and epistemic trust; (c) MBT for personality disorders, which has been shown to be particularly effective in reducing depression, self-harm, and suicidality in both adults (Bateman & Fonagy, 2008; and adolescents (Feenstra et al., 2012;Rossouw & Fonagy, 2012); and (d) MBT for psychosis, which may be a suitable approach for patients with depression who also present with psychotic symptoms (Brent et al., 2014;Debbané et al., 2016;Salaminios et al., 2024;Weijers et al., 2021). In the following sections, we briefly outline the treatment principles of MBT for personality disorders and dynamic interpersonal therapy to illustrate some of the key principles of mentalizing-focused treatments for depression across the spectrum of severity. ...

Editorial: Mentalization in the psychosis continuum: current knowledge and new directions for research and clinical practice

... Finally, as noted, MBT for depression includes a systemic component, as many adolescents with more "complex" depression need to be actively supported in bringing about changes in their own interpersonal environment. This may entail actively involving the adolescents' social system (e.g., parents, peers, teachers, mentors, pediatricians) in the treatment, as is typical of MBT in adolescents with marked personality disorder features (Remeeus et al., 2024). Family therapy is therefore a core component of MBT in adolescents toward the more severe end of the spectrum, as are outreaching interventions entailing work with the adolescents' social support system outside the treatment setting. ...

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Trials

... However, in cultures where alloparenting (children being cared for by multiple caregivers) is the norm, the development of a more generalised form of core trust in others may be what is important, as proposed by Erickson (1963) and supported by others (e.g. Fonagy et al., 2024). In both nuclear family and alloparenting contexts, sensitive responsiveness is critical (Mesman et al., 2018), and the core need to connect is common. ...

Taking stock to move forward: Where the field of developmental psychopathology might be heading

Development and Psychopathology

... The foundation of any effort to help people change is what is sometimes referred to as 'epistemic trust'. This is a person's willingness to judge new knowledge, gained from others, as trustworthy and relevant, and therefore as worth using in their lives (see Fonagy et al., 2024;Kampling et al., 2022;Talia et al., 2021). Without epistemic trust, the individual experiences an inability to modify current representations (e.g., beliefs, schemas) in the face of new knowledge. ...

Commentary: Special Issue on Interpersonal Trust
  • Citing Article
  • February 2024

Journal of Personality Disorders

... To date, little is known about the predictive factors for MBT efficacy. Three studies found that BPD severity did not influence treatment outcomes in MBT (Bateman and Fonagy 2013b;Löf et al. 2018;Smits et al. 2024). In addition, comorbid cluster C features or personality disorders were not related to MBT treatment outcomes for BPD patients, as was the case for comorbid clinical disorders (Bateman and Fonagy 2013a;Smits et al. 2024). ...

Impact of clinical severity on treatment response in a randomized controlled trial comparing day hospital and intensive outpatient mentalization-based treatment for borderline personality disorder

Personality and Mental Health

... Comorbid BN and ADHD have been investigated extensively over the past years [6,7], and comorbidity rates are estimated at 31% [8] to 35-37% [9]. BN and ADHD show common aberrations regarding neurobiological and neuropsychological factors including impulsivity [10]. ...

Borderline personality disorder: a comprehensive review of diagnosis and clinical presentation, etiology, treatment, and current controversies

World psychiatry: official journal of the World Psychiatric Association (WPA)

... Research indicate that insecure attachment may contribute to disturbances in mentalizing, leading to intrapersonal and interpersonal difficulties characteristic of PD (5). Although there are only a few studies examining the relationship between insecure attachment and impaired personality functioning within Criterion A of the AMPD (33)(34)(35), evidence suggests that attachment anxiety is a stronger predictor of impaired selffunctioning, while attachment avoidance is a stronger predictor of impaired interpersonal functioning (36). ...

The role of mentalizing in psychological interventions in adults: Systematic review and recommendations for future research
  • Citing Article
  • March 2024

Clinical Psychology Review

... By examining particular exercises in public health communication, the study demonstrated the value of considering cultural factors in enhancing communication effectiveness [38]. Such work is congruent with developmental studies on children's trust in the communication of information, indicating that children are responsive to socio-cultural signals such as similarity, accent and in-group affiliation and prosociality, as well as epistemic cues such as past accuracy, perceived experience and sound reasoning [39]. The study undertaken here seeks to make a tentative step in integrating the literature emanating from these separate disciplines (developmental science and public health) to understand how developmental experiences, in particular exposure to adversity and./or to a social environment which fails to recognise agentive selfhood, shapes social learning. ...

Epistemic trust: a comprehensive review of empirical insights and implications for developmental psychopathology

Research in Psychotherapy Psychopathology Process and Outcome

... Second, despite inconclusive evidence regarding the criterion-related validity of ET, most studies indicate nonsignificant or negligible associations between ET and relevant constructs Campbell et al., 2021;Kampling et al., 2022Kampling et al., , 2024Liotti, Milesi, et al., 2023;Tanzilli et al., 2022), with a minority substantiating its validity (Liotti, Fiorini Bincoletto, et al., 2023;Riedl et al., 2024;Riedl, Rothmund, et al., 2023), and a handful of investigations presenting mixed findings (Brauner et al., 2023;De Coninck et al., 2023;Hauschild et al., 2023;Parolin et al., 2023). Third, although good test-retest reliability was found for all three subscales, the majority of the findings demonstrated questionable internal consistency for EM (see Table 1). ...

To be a freshman during the COVID-19 pandemic: A cross-lagged model of depression, mentalizing, and epistemic trust

Personality and Mental Health