P.S. Stewart’s scientific contributions

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Publications (2)


Bacterial biofilm: A common cause of persistent infections
  • Literature Review

May 1999

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598 Reads

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7,634 Citations

Science

J.W. Costerton

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P.S. Stewart

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E.P. Greenberg

Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.


Citations (1)


... Microbial biofilms are a common cause of persistent infections associated with various body sites such as the skin or mucosal surfaces of the respiratory and digestive tract, oral cavity, etc. (Costerton et al. 1999). Bacterial biofilms are responsible for approximately 65% of all human infections (Wu et al. 2021). ...

Reference:

Prediction of SafD adhesin strong binding peptides for pilus proteins assembly suppression in the prevention of Salmonella-induced biofilm formation using virtual mutagenesis studies
Bacterial biofilm: A common cause of persistent infections
  • Citing Article
  • May 1999

Science