January 2001
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5 Reads
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28 Citations
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January 2001
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5 Reads
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28 Citations
... We have previously reported a 4% incidence of monozygotic twinning with blastocyst transfer in a multicentred study (Behr et al., 1999Behr et al., , 2000). As expected, these pregnancies are monochorionic, since with blastocyst transfer, embryo splitting occurs on or beyond day 5 after the inner cell mass has developed and cells destined to become chorion have already differentiated (Cunningham, 1997). In this patient with quadruplets, it would appear that the two transferred blastocysts led to fraternal twins, and a spontaneous conception with embryo splitting in vivo by day 4 resulted in identical twins. ...
January 2001