P. Nivethithai’s scientific contributions

Oral delivery is not possible for 50% of currently marketed drug compounds due to low oral bioavailability. One of the most popular approaches to enhance the oral bioavailability of these molecules is the utilization of a lipid based drug delivery systems. Self emulsifying drug delivery systems (SEDDS) are a class of lipid based delivery systems. Conventional SEDDS are normally prepared in a liquid dosage form that can be administered in soft gelatin capsules, which have some disadvantages especially in the manufacturing process. Accordingly, Solid-Self emulsifying drug delivery systems (Solid-SEDDS), prepared by solidification of liquid/semi-solid self emulsifying ingredients into powders in order to create solid dosage forms. This article focuses on SEDDS and solidification techniques of Solid-SEDDS.