January 1983
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3 Reads
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106 Citations
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... Early studies measuring CO by the dye dilution method in adults with severe hypertension demonstrated reduced CO and increased SVR compared to normotensive individuals [1,2]. Later studies in adults with established hypertension performed mainly in the 1980s confirmed these findings, with increased SVR (or SVR indexed to body surface area, SVRI) as the characteristic finding [3][4][5]. This has led to the view that primary hypertension is predominantly a 'vascular' rather than 'cardiac' problem. ...
- Citing Article
January 1983