P C Hohenberg's research while affiliated with Yale University and other places

Publication (1)

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We present a theoretical analysis of intracellular calcium waves propagated by calcium feedback at the inositol 1,4,5-trisphosphate (IP3) receptor. The model includes essential features of calcium excitability, but is still analytically tractable. Formulas are derived for the wave speed, amplitude, and width. The calculations take into account cyto...


... It "turns on" when the local Ca 2+ concentration C(S, T ) exceeds a spatially uniform threshold C 0 , at which point Ca 2+ is released into the cytosol at a rate J. The authors of Ref. 56 show that the speed of the traveling wave is given by Eq. (5). ...