Oren M. Tepper’s research while affiliated with Albert Einstein Medical Center and other places

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Publications (58)


Expanding Access to 3D Technology in Plastic Surgery of the Breast: Validation of the iPhone Against the Vectra H2
  • Article

August 2024

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21 Reads

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery

Hayeem L Rudy

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Yi-Hsueh Lu

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[...]

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Katie Weichman

Background The iPhone (Apple Inc, Cupertino, California) contains a high-fidelity 3D-scanner and is widely distributed in the United States. Presently, 3D analysis of the breast necessitates ownership of cost-prohibitive cameras and software packages such as the Vectra system. Objectives We compared the accuracy of 3D photos of the breast obtained with the iPhone X 3D scanner against the Canfield Vectra H2 (Canfield Scientific Inc. Parsippany, NJ) in an effort to expand access to 3D technology in plastic surgery. Methods Twenty breasts (n=20) were 3D-photographed with iPhone X and the Vectra H2 and compared with color map analysis and by measuring distances across the model between key anatomical landmarks. These distances included sternal notch to nipple (SN-N), mid-chest to nipple (M-N), nipple to mid-inframammary fold (N-IMF), and inframammary fold width (IMF). Statistical tests included the Bland-Altman Plot analysis. Results When comparing absolute differences in distances between key anatomical landmarks, the average discrepancy in measurements between iPhone and Vectra image pairs were the following: SN-N: 0.94mm, M-N: 0.70mm, N-IMF 0.81mm, and IMF 0.96mm. Colormap analysis demonstrated an average error of 1.53mm, mean of 0.53mm, and standard deviation of ±1.81mm. Bland-Altman Plot revealed a mean difference of 0.13mm and an agreement interval between -1.90 and 2.17mm. Conclusions The iPhone is capable of capturing 3D-photographs with a high level of fidelity when compared to Vectra. 3D-scans obtained with the iPhone may be useful for planning nipple position, measuring the breast footprint, choosing implants, and performing other functions using 3D technology that are typically performed using the more expensive systems.


Fig. 2. a virtual overlay and 3D-printed representation of the 3D-printed splint, respectively. a, a 3D wire mesh image with virtual nasal splint overlay created using data generated through 3D image capture. B, a customized 3D-printed splint placed on top of the nose.
Fig. 3. 3D registration of the nose. Standardized landmarks were placed on the patient's baseline image (1-week postoperative). these exact landmarks were then projected onto the subsequent time points (6-week time point shown).
Fig. 4. a color map demonstrating the difference in preoperative and postoperative edema subdivided by nasal region. the total nose was aligned along an x, y, and z axis, with (a) the z axis pointing anteriorly, parallel to the nasal tip point, and the y-axis pointing superiorly with the horizontal xz plane aligned at the level of the superior alar crease. the nasal tip and dorsum were delineated by the z plane (B) (nasal tip selected in blue).
Fig. 5. Postoperative images at 1 week and 1 year postoperative in taping group. the (a) frontal and (B) lateral view at 1 week postoperative in the taping group. the (C) frontal and (D) lateral view at 1 year postoperative.
Fig. 6. Postoperative images at 1 week and 1 year postoperative in 3D-printed splint group. the (a) frontal and (B) lateral view at 1 week postoperative. the (C) frontal and (D) lateral view at 1 year postoperative.

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Comparing Postoperative Taping vs Customized 3D Splints for Managing Nasal Edema after Rhinoplasty
  • Article
  • Full-text available

September 2023

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140 Reads

Background Significant swelling after rhinoplasty can temporarily obscure results and lead to distress for patients and surgeons. We recently developed three dimensional (3D)-printed nasal splints that aim to protect the nose and limit edema by applying gentle compression. This prospective, randomized study compares postoperative nasal edema in patients being treated with traditional taping versus 3D-printed splints. Methods Patients undergoing primary rhinoplasty (2019–2020) were randomized into two groups: taping versus 3D-printed splinting. For 12 weeks, patients either applied steri-strips to the dorsum and tip, or used 3D-printed splints, which were based on nasal simulations. The percentage change in volume (cm ³ ) was calculated for the total nose, dorsum, and nasal tip at various time points. Results Nasal taping (n = 34) demonstrated a volume reduction of 4.8%, 9.9%, 10.0%, 10.3%, and 10.6% (compared with baseline) at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year, respectively. In contrast, the resolution of swelling with 3D splints (n = 36) was 5.0%, 8.6%, 11.0%, 14.9%, and 15.1% at the same time points. Inter-group comparison showed that 3D splints led to significantly less edema of the total nose at 6 months and 1 year ( P ≤ 0.05), as well as consistent reductions in the tip and dorsum, specifically (1 year, P ≤ 0.1, 0.01, respectively). Conclusions 3D-printed splints after rhinoplasty leads to a significant reduction of edema, most noticeable at 6 months and 1 year. This study suggests that customized 3D-printed splints offer an effective clinical alternative to traditional taping to reduce postoperative edema after rhinoplasty.

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Figure 3. Percentile of radix height preferences in each age group. The y-axis shows the percentage of volunteers in each group that chose 1 of 3 choices for radix height. The x-axis shows aesthetic preference, and each age group's preference for radix height.
Figure 4. Percentile of NLA preferences in each age group. The y-axis shows the percentage of volunteers in each group that chose 1 of 3 choices for the NLA presented as images. The x-axis shows aesthetic preference, and each age group's preference for NLA.
Current Trends in Ideal Nasal Aesthetics Show Younger Patients Have a Preference Toward Longer Augmented Noses

August 2023

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84 Reads

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2 Citations

Aesthetic Surgery Journal Open Forum

Background Aesthetic norms fluctuate over time and often result in generational differences in preferred ideal nasal aesthetics. While some traditional concepts in ideal nasal aesthetic have been suggested in our literature, there is no study to date which has identified contemporary preference across different age groups. Objectives To understand the general population’s current perception of ideal nasal profiles. Methods Two dimensional (2D) images of female noses (n=10) of varying ethnicities were simulated to alter either the radix height or nasolabial angle (NLA) independently. Radix height was manipulated by increasing or decreasing the height by 5 mm relative to baseline. For NLA, 3 images were created with the following measurements: (1) 90, (2) 100, and (3) 110 degrees. Groups were categorized by generation and age at the time of completing the study: Generation Z (age 18-23), Millennial 20s (age 24-30), Millennial 30s (age 31-39), and Generation X (age 40-55). Each figure consisted of either 3 variations in radix height (n=10) or 3 variations in NLA (n=10). Within each figure, volunteers were asked to choose their preferred nose. Results The younger generations, Generation Z (Gen Z) and Millennial 20s and 30s, preferred a more augmented radix compared to Generation X (Gen X) which preferred baseline radix height. Gen Z, Millennial 20s, and Gen X preferred a 90-degree NLA while Millennial 30s preferred a NLA of 100-degrees. Conclusions The authors found that younger populations (Gen Z, Millennial 20s, and Millennial 30s) preferred a more augmented appearance to the nasal radix and, on average, a more acute NLA than published data suggests.


Topical Tranexamic Acid Does Not Reduce The Incidence Of Hematoma In Reduction Mammoplasty: A Double-Blinded, Randomized Placebo-Controlled Trial

July 2023

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24 Reads

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11 Citations

Plastic & Reconstructive Surgery

Background: Breast reduction mammoplasty (BRM) is among the most common procedures in plastic surgery, with a 1-7% postoperative hematoma incidence reported. Tranexamic acid (TXA) has been shown to reduce perioperative bleeding and need for transfusion when administered intravenously or topically, but remains underutilized in plastic surgery. This study aims to investigate whether topical administration of topical TXA reduces postoperative hematoma following BRM. Methods: A double-blinded, randomized controlled trial of 98 patients (196 breasts) undergoing bilateral primary reduction mammoplasty at a single academic institution was performed. Patients were used as internal matched controls, with one breast randomized to receive 1000mg of topical TXA before closure, and the other receiving saline. All members of the surgical team and patient were blinded as to which breast received the study drug. Postoperative complications, including hematoma, within 30 days of surgery, drain outputs, and duration of drain use, were compared between treatment and placebo breasts. Results: The overall hematoma rate was 1.5%. There was no significant association between application of TXA and development of a hematoma (p=0.56) or other complications. The hematoma rate of patients enrolled in the trial was similar to the overall rate of hematoma during the study time period (1.5% versus 2.4%, p=0.511). In a multivariate model, TXA was not significantly associated with differences in drain output after controlling for resection weight, age, and duration of drain use (p=0.799). No adverse effects or thromboembolic events from TXA were observed. Conclusion: Topical application of TXA does not decrease the incidence of hematoma following reduction mammoplasty.



Commentary on: The Management of Lumps, Bumps, and Contour Irregularities (LBCs) of the Lower Eyelid and Cheek After Poor Outcome Fat Transfer

March 2023

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5 Reads

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1 Citation

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery

See the Original Article here. We very much enjoyed reading the manuscript entitled “The Management of Lumps, Bumps, and Contour Irregularities (LBC) of the Lower Eyelid and Cheek After Poor Outcome Fat Transfer.” This manuscript serves as a valuable addition to our literature, and sheds light on a very important yet challenging area in facial aesthetic surgery. The eyelid-cheek junction has long been an area of both great interest and frustration for aesthetic surgeons. Various approaches to create a more youthful appearance have been described, ranging from excision of fat, redistribution of fat, addition of volume (ie, filler, fat), or some combination of these. In recent years, fat grafting has gained favor among patients and surgeons alike due to the relative ease of fat harvest, minimal downtime, and long-lasting results. Despite fat grafting being considered a relatively minimally invasive procedure, it is a highly nuanced technique that is not without risk, with the most common complications being visibility and palpability.


The Impact of Alar Flare Reduction Goes Beyond Just the Ala

February 2023

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16 Reads

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2 Citations

Plastic & Reconstructive Surgery

Introduction: Alar flare reduction (AFR) is a widely utilized technique in rhinoplasty. While the impact of AFR on the alar base has been well studied, its effect on the surrounding tissues is largely unknown. This study aims to elucidate the potential effect of AFR on the overall nasal and peri-nasal anatomy. Methods: AFR was performed on cadavers (n=7) with sequential crescent shaped alar excisions of 2, 4 and 6mm. 2D and 3D-photographs were obtained at baseline and subsequent intervals. Analysis was performed with Adobe Photoshop and Vectra. Standardized landmarks were placed at the nasal tip point (NTP) and alar base point (ABP) to quantify NTP vector distances, NTP surface distances, and alar crease angle. Results: The surface and vector distances between the NTP and ABP decreased for increasing AFR intervals. AFR created a surface decrease of 1.90±1.60, 3.54±1.85, and 4.91±1.89mm respectively. AFR created a vector decrease of 1.50±1.14, 2.83±1.37, and 3.97±1.38mm respectively. NTP projection decreased by 0.54±0.31mm for 6mm excision. AFR led to cheek elevation of 0.87±0.70, 1.25±0.60, and 1.96±0.48mm respectively. This alar crease elevation blunted the transition between the cheek and upper lip skin at the level of the alar rim with the angle of this transition increasing 26.62±12.78 degrees from baseline to 6mm. Conclusions: 3D-analysis demonstrates the influence of AFR on the alar base and surrounding peri-nasal contour. AFR results in nasal tip de-projection, alar crease elevation, and alar flare width narrowing. Further investigation into the impact of modifying the alar base on surrounding structures is warranted.


Virtual Surgical Planning and Three-Dimensional Printing in Rhinoplasty

December 2022

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10 Reads

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2 Citations

Seminars in Plastic Surgery

Recent developments in three-dimensional (3D) imaging technology offer a more comprehensive means of assessing facial features. 3D printing allows for the transition of planning from simply a preoperative tool to an intraoperative device with the use of tools such as 3D-printed cutting guides, marking guides, or positioning guides. With the advent of 3D printing technology, 3D surface images can now be used to generate new medical models, devices, or tools to assist with rhinoplasty during preoperative, intraoperative, and postoperative phases. In the field of rhinoplasty, 3D printing can be applied in three main areas: (1) reference models, (2) surgical guides, and (3) nasal splints. The value of 3D imaging extends far beyond the benefits of “conversion” during a preoperative consultation and has the potential to greatly enhance the overall treatment of rhinoplasty patients with enhanced communication and personalized devices that can be used during surgery and in the postoperative phase.



Three-Dimensional Perioral Assessment Following Subnasal Lip Lift

March 2022

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22 Reads

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6 Citations

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery

Background The sub-nasal lip lift is a surgical technique that elevates the “lip line” (interface between vertical maxillary incisor height and upper lip) to achieve a more youthful aesthetic. Objectives This study offers the first ever definition of 3D changes to the upper lip due to sub-nasal lip lift. Methods A lip lift procedure was performed (on cadaveric samples) in a sequential manner from 2.5mm to 5.0mm intervals (n=13). 3D photographs were taken using the VECTRA H1 system (Canfield Scientific, Fairfield, NJ), and 3D analysis was performed including vermillion height and width, philtral height, sagittal lip projection, vermillion surface area, and incisor show. A subset of samples (n=9) underwent a modification of the technique by undermining of the upper lip subcutaneous tissue off of the underlying muscular fascia. Results Vermillion surface area (baseline ranged from 1.45 - 5.52 cm 2) increased by an average of 20.5% and 43.1% with 2.5 mm and 5.0 mm lip lift, respectively. Anterior projection of the vermillion increased in all cases by an average of 2.13mm and 4.07 mm at 2.5 and 5.0 mm respectively. Philtral height decreased in all cases by an average of 3.37 and 7.23 mm at 2.5 and 5.0 mm, whereas incisal show increased on average of 1.9 and 4.09 mm, respectively. Conclusions This study is the first to define the 3D morphometric changes to the upper lip following sub-nasal lip lift. Quantifying these changes aids the surgeon in both preoperative planning and guiding patient expectations.


Citations (29)


... While Gen Z, Millennials in their 20s, and Gen X preferred a 90-degree nasolabial angle, Millennials in their 30s leaned toward a 100-degree angle. 8 A 2024 cross-sectional study of 197 individuals from Canada, Saudi Arabia, Kuwait, and Lebanon revealed mean ideal nasolabial angles of 97.1 ± 6.39 degrees for males and 109.5 ± 5.32 degrees for females. 9 Identifying the ideal nasal profile is crucial for establishing patient-centered aesthetic goals. ...

Reference:

Exploring ideal nasal aesthetics in Thailand: Trends and participants’ awareness of rhinoplasty
Current Trends in Ideal Nasal Aesthetics Show Younger Patients Have a Preference Toward Longer Augmented Noses

Aesthetic Surgery Journal Open Forum

... [1][2][3] The complications associated with postoperative fluid can lead to unplanned operations, blood transfusions due to acute blood loss anemia, infection, delayed wound healing, and an adverse effect on the overall surgical outcomes. 4 Tranexamic acid (TXA) has gained popularity among plastic surgeons for its potential to reduce postoperative hematoma and seroma formation. [5][6][7][8] Since its introduction in the 1960s, TXA has been used to reduce intraoperative bleeding and subsequent complications across various surgical fields, including orthopedic, trauma, craniofacial, and cardiac surgery. ...

Topical Tranexamic Acid Does Not Reduce The Incidence Of Hematoma In Reduction Mammoplasty: A Double-Blinded, Randomized Placebo-Controlled Trial
  • Citing Article
  • July 2023

Plastic & Reconstructive Surgery

... The advantage of an internal excision is that the scar is concealed, but for nasal wings with a vertical nasal axis, the traditional internal excision method tends to change the direction of the nasal wing axis, forming a bowling ball-like nasal wing appearance (Figure 8). The nasal axis is an important component in nasal reduction surgery [11,12]. According to the position of the vertical surface of the nasal lobules relative to the horizontal plane of the nasal base, the nasal axis can be divided into three forms: the abductor type, the vertical type and the introverted type. ...

The Impact of Alar Flare Reduction Goes Beyond Just the Ala
  • Citing Article
  • February 2023

Plastic & Reconstructive Surgery

... This wide range of preferences emphasizes the importance of patient involvement in the decision-making process. 2 Previous studies have shown that while a minority of the population meets aesthetic ideals, these individuals still have subjectively attractive faces. 3,4 This underscores the point that patient satisfaction ultimately depends on the patient's perception of the result and requires the surgeon to incorporate the patient's aesthetic preferences into their surgical plan. ...

Virtual Surgical Planning and Three-Dimensional Printing in Rhinoplasty
  • Citing Article
  • December 2022

Seminars in Plastic Surgery

... The perioral region is significant in conveying one's age, contributing to facial attractiveness and beauty [1][2][3][4][5], and is gaining more interest during the COVID-19 pandemic [6]. A youthful and attractive perioral region consists of a relatively shorter upper lip with soft tissue projection [7,8] whereas the most significant senile alterations are upper lip lengthening and shape deformities [9]. Furthermore, these aging traits might occur on the lips of younger people due to hereditary [10,11], who may seek to change their appearance [12]. ...

Three-Dimensional Perioral Assessment Following Subnasal Lip Lift
  • Citing Article
  • March 2022

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery

... Meanwhile, the AR hologram provides an overall view of preoperative planning information. Such technique has been used in Neurosurgery, Orthopedics, Plastic Surgery, and Oral and Maxillofacial Surgery (9)(10)(11)(12)(13). However, few studies focused on the effect of AR surgical navigation on vector transfer in maxillary DO. ...

Intraoperative Navigation in Plastic Surgery with Augmented Reality: A Preclinical Validation Study
  • Citing Article
  • March 2022

Plastic & Reconstructive Surgery

... Nasal filler injection remains one of the highest risk areas for blindness, as described in the recent update by Doyon et al. [19]. Nasal ultrasound anatomy and vascular anatomy have been described in multiple publications [20][21][22][23][24]. ...

Commentary on: The Layered Anatomy of the Nose: An Ultrasound-Based Investigation
  • Citing Article
  • November 2021

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery

... AI algorithms trained to recognize specific patterns in 3D scans will be able to identify unique characteristics of the lips with high precision, accelerating the identification process and further reducing operator-dependent errors [10,12]. The possibility of applying AI algorithms for the automatic recognition of lip impressions could also reduce the need for manual interpretations, improving the overall efficiency of the process [31]. ...

Turning Back the Clock with Lip Lift: Quantifying Perceived Age Reduction Using Artificial Intelligence
  • Citing Article
  • July 2021

Facial Plastic Surgery & Aesthetic Medicine

... Essa tecnologia permite criar modelos tridimensionais detalhados do nariz do paciente, facilitando simulações cirúrgicas préoperatórias que auxiliam no ajuste preciso do plano cirúrgico (Zhang et al., 2023;Ashok;Acharya;Nayani, 2024). Os modelos 3D também são usados para produzir guias cirúrgicas personalizadas, que ajudam no posicionamento e na modelagem dos tecidos com maior precisão (Gordon et al., 2021). Com essas ferramentas, os cirurgiões podem realizar procedimentos com maior segurança e previsibilidade, adaptando-se melhor às particularidades anatômicas de cada paciente, resultando em intervenções mais personalizadas e eficazes (Amanullaev et al., 2023). ...

3D Printed Surgical Guides Applied in Rhinoplasty to Help Obtain Ideal Nasal Profile
  • Citing Article
  • June 2021

Aesthetic Plastic Surgery

... These studies found comparable accuracy between the two methods [6,11,13]. To examine the accuracy of face scanners, some studies have compared them with previously established face scanners, like the 3dMDface or the Vectra H1 [8,13,14]. Others have employed extraoral scanners, like the D2000, the Faro Design Sca-nArm 2.0, or the Classic iCAT, to create reference scans [10,15,16]. Some studies have also employed original model files as a reference, used to 3D-print a head model for testing [6,7]. ...

3D Facial Scanning at the Fingertips of Patients and Surgeons: Accuracy and Precision Testing of iPhone X 3D Scanner
  • Citing Article
  • September 2020

Plastic & Reconstructive Surgery