Ognjen Kraus's research while affiliated with University of Zagreb and other places

Publications (74)

Article
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Smjernice se odnose na klasifi kaciju, dijagnostiku i liječenje sindroma prostatitisa. Njihov su cilj standardizacija, izjednačavanje i optimalizacija dijagnostike, liječenja i praćenja bolesnika s prostatitisom koji će dovesti do poboljšanja kvalitete zdravstvene zaštite ovih bolesnika te promovirati racionalnu potrošnju antibiotika. Namijenjene s...
Article
Micropapillary urothelial carcinoma (MPUC) is a rare aggressive variant of urothelial carcinoma, associated with advanced tumor stage, high tendency to invade lymphovascular spaces, and metastasize to lymph nodes and other organs. Therefore, it has a poor prognosis. One of the most prominent histological features is the presence of small, round emp...
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S indrom prostatitisa čest je klinički entitet i naziv je za niz poremećaja funkcije prostate.1,2 O sindromu prostatitisa govorimo stoga što etiologija bolesti nije u potpunosti razjašnjena, a dijagnostički i terapijski kriteriji nisu jasno određeni.3-5 Sindrom prostatitisa najčešći je urološki problem u muškaraca mlađih od 50 godina i treći najčeš...
Article
Literature data support the hypothesis that oxidative stress and the accompanying antioxidant defense might play an important role in renal cell carcinoma (RCC) growth and progression. It is also known that the incidence of renal tumors is two times higher in men than in women. Thus, the aim of this study was to determine whether the oxidant/antiox...
Conference Paper
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Introduction & Objectives: In recent publications there is emerging evidence that inflammation may contribute to prostatic carcinogenesis. It is hypothesised that oxydative stress triggers the appearance of proliferative inflammatory atrophy (PIA) lesions which can degenerate into carcinoma. The aim of the study was to assess the risk of detecting...
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Introduction & objectives: The aim of the study was to determine whether the total percentage of carcinoma in needle core biopsy and localization of carcinoma in the prostate could be used as reliable predictors of biochemical relapse (BCR) in patients treated with radical prostatectomy.
Article
Urothelial (transitional cell) tumors account for about 90% of all bladder tumors. Their presentation varies from benign lesions that rarely recur to highly malignant tumors. Inverted (endophytic) growth pattern in urothelial carcinoma is particulary hard to distinguish from inverted papilloma. Morphologic criteria alone are not enough and immunohi...
Article
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Although prostatitis can contribute to the lack of prostate specific antigen (tPSA) specificity, there is disagreement concerning the effect of histological inflammation on free PSA (fPSA). We investigated the correlation between aggressiveness of histological inflammation and tPSA, fPSA and f/tPSA in patients without detectable prostate cancer (PC...
Conference Paper
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Karcinom prostate je jedan od vodećih zdravstvenih problema muškaraca druge i tre¬će životne dobi. Na njega otpada značajan udio od ukupnog broja svih malignih bolesti u muškaraca starijih od 50 godina, a incidencija se povećava svakim desetljećem, te je on na Zapadu najčešća maligna bolest muške populacije i drugi uzrok smrti. Nagli porast inciden...
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A rare case of posttraumatic high-flow priapism is presented. A 20-year-old man underwent diagnostic procedure with color Doppler sonography and angiography. On color Doppler sonography and selective and supraselective angiographic images, arteriocavernosal fistula and pseudoaneurysm were detected in the proximal part of the right cavernous body. C...
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Unlabelled: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) represents the most common form of prostatitis. No known etiology factor in most cases can be found. It is possible that at least in some cases autoimmune response could be causative factor. Common treatment options include antibiotics, alpha blockers, myorelaxants, phytotherap...
Article
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A rare case of posttraumatic high-flow priapism is presented. A 20-year-old man underwent diagnostic procedure with color Doppler sonography and angiography. On color Doppler sonography and selective and supraselective angiographic images, arteriocavernosal fistula and pseudoaneurysm were detected in the proximal part of the right cavernous body. C...
Article
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Aim: Urothelial (transitional cell) tumors account for about 90% of all bladder tumors. Their presentation varies from benign lesions that rarely recur to highly malignant tumors. Inverted (endophytic) growth pattern in urothelial carcinoma is particulary hard to distinguish from inverted papilloma. Morphologic criteria alone are not enough and imm...
Conference Paper
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Introductions and objectives: On transrectal ultrasound (TRUS), prostate cancers are visualized as hypoechoic or isoechoic lesions. Hyperechoic lesions are usually considered as benign, whether benign prostate hyperplasia (BPH), prostatitis or prostate infarction. On TRUS, prostate cancer is visualized as a hypoechoic lesion in 60-70%, and as isoec...
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An extremely rare case of seminal vesicle cyst associated with ipsilateral renal dysplasia and ectopic ureter is presented. A 36-year-old patient underwent nephroureterovesiculectomy. Considering the clinical and imaging profile of the patient, a diagnosis of ureterocele with megaureter was initially suspected, but intraoperative findings and defin...
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We demonstrate the evolution of the clinical presentation and outcomes for patients with clinically localized prostate cancer (PC) treated with radical retropubic prostatectomy (RRP) at our department, emphasizing epidemiologic significance of changes during the 10-year period. We assessed the annual trends for changes in patients age, preoperative...
Article
Micropapillary urothelial carcinoma (MUC) is a rare variant of urinary bladder carcinoma associated with highly aggressive behaviour. The aim of this study was to analyse clinicopathological features of MUC particularly a relationship between pathological stage at presentation and proportion of micropapillary component (MPC) in 10 patients with MUC...
Article
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An extremely rare case of seminal vesicle cyst associated with ipsilateral renal dysplasia and ectopic ureter is presented. A 36-year-old patient underwent nephroureterovesiculectomy. Considering the clinical and imaging profile of the patient, a diagnosis of ureterocele with megaureter was initially suspected, but intraoperative findings and defin...
Article
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To estimate the incidence of transrectal ultrasound (TRUS) hyperechoic lesions and of hyperechoic prostate cancer in TRUS-guided biopsy specimens. We prospectively studied 200 patients with total prostate-specific antigen values less than 20 ng/mL and/or positive results on digital rectal examination who had undergone TRUS-guided prostate biopsy. E...
Conference Paper
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Introduction & Objectives. Purpose of this report is to evaluate our experience in the management of localized prostate cancer (PC) with radical retropubic prostatectomy (RRP). Changes and advances in patient selection criteria and clinical outcome data are evaluated and discussed emphasizing epidemiologic significance of annual changes over ten ye...
Conference Paper
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OBJECTIVE: In clinical practice, we are often confronted with a patient in so called “grey zone” (PSA<10 ng/ml) with a decreased free PSA levels, whose biopsies reveal no malignancy but only inflammation. We investigated the relationship between histological inflammation and total PSA (tPSA), freePSA (fPSA) and percent-free PSA (f/tPSA) levels in p...
Article
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Serum levels of total prostate specific antigen (t-PSA) and PSA complexed to antichymotrypsin (PSA-ACT), as well as their corresponding density parameters were measured in prostate cancer (PC) candidates for radical prostatectomy. In these patients blood Chromogranin A (CgA) values were also recorded. The PSA-ACT recordings in presurgically charact...
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We report a patient with ipsilateral synchronous renal cell carcinoma and urothelial carcinoma of the left renal pelvis and ureter. The patient underwent nephrectomy 9 years earlier due to renal cell cancer of the right kidney. Only 25 cases of ipsilateral synchronous renal cell carcinoma and urothelial carcinoma have been reported in the literatur...
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SUMMARY – Two cases of adrenal ganglioneuromas associated with ipsilateral primary kidney cancer, according to literature review a very rare combination, are presented. Both patients underwent adrenalectomy and nephrectomy. Specimens were formalin fixed, paraffin embedded, cut at 5 µm and routinely stained with hematoxylin and eosin. Primary antibo...
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Despite the increasing number of patients being detected with a clinically localized (T1,2) prostate cancer, pelvic lymphadenectomy remains a standard in determining the exact histological staging as a reliable prognostic parameter. Extended lymphadenectomy is superior to limited lymphadenectomy, and with the use of appropriate surgical technique d...
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A rare case of bladder hemangioma showing spontaneous regression in 35-year-old man is reported. After biopsy and fulguration, the hematuria disappeared. The specimen was pathologically diagnosed as cavernous hemangioma. To establish the extent of tumor pelvic angiography was performed and showed no vascular activity in tumor. Lack of vascular acti...
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Asian Journal of Andrology, the top clinical research journal based in China, is a print and online publication that focuses on new basic and clinical (including modern, traditional and epidemiological) research on andrology
Conference Paper
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Introduction & Objectives: Inflammation is a frequent pathological finding in prostate biopsies, performed on men without prostatic malignancy or clinical prostatitis. Although it is known that inflammation can contribute on lack of PSA specificity, there is disagreement in the effect of subclinical, histological inflammation on free PSA values. In...
Conference Paper
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Introduction & Objectives: Transrectal ultrasound guided prostate needle biopsy is the most important diagnostic procedure for early prostate cancer detection. It is a safe diagnostic tool with very few complications and well tolerated by the patients. The aim of the study is to report complication rates after transrectal ultrasound guided prostate...
Article
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Results of ureteral reimplantation in infants with primary vesicoureteral reflux (VUR) were retrospectively reviewed and evaluated. From January 1991 till December 2000, a total of 156 patients with primary VUR underwent ureteral reimplantation at University Department of Urology, Sestre milosrdnice University Hospital, Zagreb, Croatia. The indicat...
Article
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Transrectal ultrasound guided prostate needle biopsy is the most important diagnostic procedure for early prostate cancer detection. It is a safe diagnostic tool with very few complications and well tolerated by patients. The aim of the study is to report complication rates after transrectal ultrasound guided prostate needle biopsy. All study patie...
Article
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Prostate cancer continues to be a source of considerable morbidity and mortality for aging men. In recent publications there is emerging evidence that prostate inflammation and/or infection may contribute to prostatic carcinogenesis. Chronic subclinical inflammation is thought to incite carcinogenesis by causing oxidative cell and genome damage, pr...
Article
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Recommendations for antimicrobial treatment and prophylaxis of urinary tract infections (UTI) have been made according to study results on the resistance of the most frequent causative agents of UTI to antimicrobial drugs. The Committee for monitoring bacterial resistance to antibiotics in the Republic of Croatia has been conducting this study sinc...
Article
Recommendations for antimicrobial treatment and prophylaxis of urinary tract infections (UTI) have been made according to study results on the resistance of the most frequent causative agents of UTI to antimicrobial drugs. The Committee for monitoring bacterial resistance to antibiotics in the Republic of Croatia has been conducting this study sinc...
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Due to the rarity of multiple primary synchronous malignancies, the correct and concurring data on their incidence are extremely difficult to find. Recent studies point to renal cell carcinoma as a tumor showing most prominent association with other types of simultaneous or metachronous primary carcinoma. To our knowledge, this is the first case of...
Conference Paper
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INTRODUCTION AND OBJECTIVES: Purpose of this report is to evaluate our experience in radical retropubic prostatectomy. We retrospectively evaluated the preoperative and postoperative data of patients who underwent radical prostatectomy for localised prostate cancer. Changes and advances in patient selection criteria over time and clinical outcome d...
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True hermaphroditism represents a heterogeneous condition in terms of its phenotypic presentation and genetic background. There is a wide spectrum ranging from frankly male to frankly female external genitalia, however, with a predominance of ambiguity. The most frequently observed karyotype is 46,XX, followed by various types of chromosome mosaici...
Conference Paper
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Infekcije mokraćnog sustava ubrajaju se u najčešće bakterijske infekcije, uzrok su značajnog morbiditeta i jedan su od najčešćih razloga propisivanja antimikrobnih lijekova. Oko 50% žena najmanje jedanput u životu ima akutnu infekciju donjih mokraćnih puteva. Cilj terapije je nestanak kliničkih simptoma i iskorjenjivanje infekcije u svrhu sprečavan...
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Radical prostatectomy is a treatment of choice for localized prostatic adenocarcinoma. In most cases, radical prostatectomy is combined with pelvic lymph node dissection. During the last decade, the necessity to perform lymphadenectomy in all patients has been questioned. Lymph node dissection adds the risk of complications, and increases operation...
Article
To determine differences in systemic stress responses in patients undergoing three different types of surgery for benign prostatic hyperplasia (BPH), evaluated by measuring levels of stress variables, i.e. cortisol; acute-phase reactants, i.e. C-reactive protein (CRP) and fibrinogen; and antioxidants, i.e. total antioxidant status (TAS) and superox...
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An exceedingly rare case of a patient with osteogenesis imperfecta and prostate cancer is reported. The patient underwent radical prostatectomy, which had to be stopped due to the extremely narrow space for surgical manipulation. The clinical, diagnostic and operative peculiarities of the case are presented and the relevant literature reviewed.
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Objective: Fusion anomalies of the kidney are rarely encountered and the association of malignant tumors with such conditions is exceedingly rare. Association of tumors with horseshoe kidney is also uncommon, with fewer than 200 cases having been reported in the literature, and the association of tumors with crossed‐fused ectopia is even rarer, wit...
Conference Paper
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Introduction & Objectives: A case of cystic metanephric adenoma (MA) is presented to increase awareness among urologists of this rare entity. MA is extremely rare and its diagnosis should be considered in a patient with well circumscribed multilocular mass. A little more than 80 cases were reported in the literature, but only few illustrated radiol...
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Crossed-fused renal ectopia is an uncommon condition and cases of malignant tumors in such anomalies are extremely rare. A case of renal cell carcinoma in a patient with crossed-fused-ectopia is reported. The patient was successfully treated with partial nephrectomy following isthmus division. Radiologic investigations and operative findings are pr...
Article
Recommendations for antimicrobial treatment and prophylaxis of urinary tract infections (UTI) have been made according to the results of investigation of resistance of the most frequent causative agents of UTI to antimicrobial drugs. This investigation has been conducted for the past seven years by the Committee for monitoring bacterial resistance...
Article
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The purpose of this report is to show our own results of repeat transrectal ultrasound guided biopsies, with special reference to the prevalence of newly diagnosed carcinoma in the transition zone of the prostate. Transrectal ultrasound guided repeat biopsies (six cores laterally plus two cores from transition zones) were performed in 64 patients....
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-In the last decade there has been an exponential rise in the number of patients diagnosed with prostate cancer, probably because of an increase in life expectancy and therefore an expanding popu-lation of men in the susceptible age range (>50 years). Prosmte cancer is a significant cause of morbidiry and mortaliry. The widespread use of diagnostic...
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-Prostate cancer is a significaot cause of morbidiry and mortaliry The natural aging of rhe population and widespread use diagnostic tests such as prostate specific antigen have led to an increase in the numbers ofmen diagnosed with localized prostate cancer Screening to identify organ-confined disease has attracred much public and scientific atten...
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Primary extragonadal germ cell tumors are rare neoplasms affecting young males. They usually present with abdominal retroperitoneal, mediastinal mass with varying symptoms. The rarest among these rare extragonadal germ cell tumors are embryonal cell carcinomas. Three cases of embryonal cell carcinomas are presented to show that the clinical present...
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Fusion anomalies of the kidney are rarely encountered and the association of malignant tumors with such conditions is exceedingly rare. Association of tumors with horseshoe kidney is also uncommon, with fewer than 200 cases having been reported in the literature, and the association of tumors with crossed-fused ectopia is even rarer, with only four...
Article
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Long term efficacy of transurethral incision of the prostate (TUIP) was evaluated in selected patients. A total of 50 patients with symptoms of bladder outlet obstruction caused by smaller benign prostates (estimated weight 30 g or less) were assigned to TUIP. Bilateral incision at "5 and 7" o'clock position was performed in all patients. Preoperat...
Article
The diagnosis of prostatic adenocarcinoma in needle core biopsy is based on major and supportive criteria. One of the supportive criteria is the presence of retraction clefting around neoplastic glands. We analyzed a series of 137 prostatic cancer cases diagnosed by needle core biopsy to determine the frequency, extent and criteria for periacinar r...
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The aim of the study was to compare Gleason scores obtained from sextant preoperative prostate biopsy and radical prostatectomy specimens in patients with localized prostate cancer. Seventy-three patients with prostate biopsy and operated on at our hospital from 2000 till 2002 were included in the study. Definitive postprostatectomy Gleason score w...
Article
A total of 37 patients with well-documented benign prostatic hypertrophy (BPH) were referred to finasteride. In all subjects the prostate volume was > 60 cc. Serum total PSA (TPSA) and free/total PSA (%FPSA) values were recorded at 3-month intervals. After 6 months of treatment, the patients were divided into two groups in accordance with the numer...
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To analyze long-term effects of short and shallow incision of the prostate, a new modification of transurethral incision of the prostate (TUIP), as a method of resolving bladder outlet obstruction and preserving anterograde ejaculation and potency. Fifty patients with symptoms of bladder outlet obstruction caused by a small benign prostate tumor of...
Article
Liposarcoma of the spermatic cord is rare and is usually discovered during hernia repair operation. We report a 71-year-old patient with spermatic cord liposarcoma. The patient presented with a painless mass in the left scrotum measuring up to 25 cm. The mass had gradually been enlarging during the last 6 months. Clinical examination suggested ingu...
Conference Paper
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AIM: to analyze preoperative and postoperative values of prostate cancer stage (TNM) and grade (Gleason score) in our patients PATIENTS AND METHODS: 111 patients aged 50-75 years (mean 62.5 yr) diagnosed with prostate cancer were assigned to radical prostatectomy between 1996 and 2001. Preoperatively all patients had digitorectal examination (posi...
Article
Objective: We report a case that we believe to be the largest example of a testicular mixed germ cell tumor with a clearly defined histology pattern. Clinical presentation and interventions: A 21-year-old patient consulted a urologist concerning a giant testicular mass. At the time of presentation the tumor measured 29 x 20 x 16 cm, with a weigh...
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Twenty patients with newly diagnosed advanced prostatic cancer were treated with monthly injections of a long-acting depot preparation of a luteinizing hormone-releasing hormone analog (triptorelin). The objective of the study was to assess the efficacy, safety and tolerability of the medication used during at least 24 months. Serum testosterone le...
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Balkan endemic nephropathy (BEN) is an acquired, environmental, polytopical disease of the entire urinary tract, with long latency. Tubulointerstitial chronic nephritis, urotheliomas of all localities, and renal cell carcinoma occur with a significantly higher frequency in the affected population. These represent only clinical manifestations of one...
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Twenty years' experience in the substitution of an isolated sigmoid segment after radical cystectomy for bladder carcinoma is described. The indication for surgery was isolated, non-transitional cell bladder cancer. The isolated sigmoid segment is placed longitudinally in the isoperistaltic direction. The study is made up of 73 cases. This operatio...
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409 cases of superficial bladder carcinoma (pTa, pTi, Tis) are reported. They are divided into three groups: 171 patients treated by TUR alone, 124 treated by TUR and local thio-TEPA, and 114 patients treated by TUR and BCG vaccine locally. It was found that the frequency of recurrence fell by 56.7, 41.9 and 26.3%, while the progression of the illn...