Ofelia Romero-Cerecero's research while affiliated with Mexican Institute of Social Security and other places

Publications (25)

Article
Ageratina pichinchensis is utilized in traditional medicine for the treatment of dermatomycosis and inflammation. The aim of this study was to evaluate the clinical and mycological effectiveness of the topical administration of an enecalin standardized extract of A. pichinchensis for treating onychomycosis in patients with type 2 diabetes mellitus...
Article
Background: Anxiety is one of the most common mental disorders. It has an impact on the decrease of productivity, the affectation of quality of life, and the increase in health care costs. The study of plant species with medicinal properties to treat anxiety has made significant progress, since they have been evaluated through in vitro, in vivo an...
Article
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Objective: To evaluate the antidepressant effect of Bauhinia blakeana and a standardized fraction in the forced swimming test on mice with neuro-inflammation induced with lipopolysaccharides (LPS). Materials and methods: Evaluation of the antidepressant effect of Bauhinia blakeana hydroalcoholic extract (BbHA) and its fractions was carried out i...
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Galphimine-B (G-B), a compound isolated from Galphimia glauca , has been shown to possess important anxiolytic activity. In this study, we evaluated the effectiveness and tolerability of a G-B standardized extract (experimental treatment) that was administered daily for 10 weeks in patients with moderate or severe Generalized Anxiety Disorder (GAD)...
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Social anxiety is one of the most common disorders found in the population attending the first level of health care. Galphimia glauca has been used for many years in Mexican traditional medicine to treat “nervous disorders”. A standardized extract of this species has been evaluated in clinical studies that have proven its efficacy and safety in pat...
Article
Previous clinical studies have demonstrated the antifungal effectiveness of Ageratina pichinchensis extracts when topically administered to patients with dermatomycosis. The objective of this study was to evaluate the effectiveness and tolerability of a 7% standardized extract of A. pichinchensis (intravaginal) in patients with vulvovaginal candidi...
Article
The plant species Ageratina pichinchensis (Schauer) R.M.King & H.Rob. (Asteraceae) in a wild plant native to Mexico that is utilized in traditional medicine for the treatment of skin problems and for mouth ulcers. The objective of the present study was to evaluate the clinical effectiveness and therapeutic safety of a phytopharmaceutical elaborated...
Article
Previous works have shown that extracts obtained from Ageratina pichinchensis are capable of reducing the time needed for wounds to heal. By means of a randomized, double-blind pilot study, the objective of this work was to evaluate the effectiveness and tolerability of a phytopharmaceutical developed with a standardized extract (5 %, cream formula...
Article
The aerial parts of Ageratina pichinchensis are used in Mexican traditional medicine for the treatment of skin wounds. Recently, it was demonstrated that the aqueous extract of this plant reduced the time required to cicatrize a wound induced in the rat. The same extract showed a capability to induce overgrowth in normal fetal lung cells (MRC-5). T...
Article
Ethnopharmacological relevance: Sphaeralcea angustifolia Cavanilles & Don (Malvaceae), known in Mexico as "Vara de San José", is used in Mexican Traditional Medicine as an anti-inflammatory and, more specifically, for treating rheumatism. Anti-inflammatory properties have been demonstrated in different pharmacological models. Aim of the study: T...
Article
Onychomycosis is a high-prevalence infectious disease that is usually treated with drugs administered chronically via the oral pathway, which produce important side effects. Ageratina pichinchensis, used in traditional medicine to treat dermatophytosis, has shown antifungal activity against Thrichophyton rubrum, and T. mentagrophytes. Clinically, a...
Article
Interdigital tinea pedis is the most frequent presentation, as well as the most severe clinical form of tinea pedis, constituting a therapeutic challenge. The aim of the study was to evaluate the effectiveness and tolerability of two concentrations of Ageratina pichinchensis extract (encecalin content, 0.76 and 1.52%, respectively) on patients with...
Article
The aerial parts of the species Ageratina pichinchensis, popularly known as "axihuitl", have been empirically used in Mexico for wound-healing purposes. The evaluation of an extract from A. pichinchensis (in an in vivo model) demonstrated its capacity to reduce, in a significant manner, the time required for wound healing in rodent skin. This same...
Article
Full-text available
The species Ageratina pichinchensis (Asteraceae) has been used for a long time in Mexican traditional medicine for the treatment of different skin conditions and injuries. In this study, the healing capacity of the plant extracts obtained was evaluated and, in order to understand the mechanism of healing, we also analyzed its effect on cell prolife...
Article
The plant species Ageratina pichinchensis has been used, for many years, in Mexican traditional medicine for the treatment of superficial mycosis. This study compared the therapeutic effectiveness and tolerability of two concentrations of the standardized extract from Ageratina pichinchensis (12.6 and 16.8%) on patients with clinical and mycologica...
Article
Aerial parts of AGERATINA PICHINCHENSIS have been used, in Mexican traditional medicine, as a remedy for the treatment of skin mycosis. Onychomycosis, also known as tinea of the nails or tinea unguium, constitutes an infection of the nails produced by dermatophytes. Clinically, onychomycosis is manifested by changes on the color, texture and thickn...
Article
to analyze the knowledge about phytopharmaceuticals of specialists affiliated to secondary care hospitals in the State of Morelos, Mexico. Material and methods: the study was conducted through a survey in which 278 medical doctors participated. They were randomly selected from Instituto Mexicano del Seguro Social (IMSS), Sistema de Salud de Morelos...
Article
Ageratina pichinchensis has been used for many years in Mexican traditional medicine for the treatment of superficial mycosis. Previous studies have demonstrated the antifungal effectiveness of a hexane extract from aerial parts of this plant on in vitro cultures of Candida albicans, Aspergillium niger, Trichophyton mentagrophytes, and Trichophyton...
Article
Background: Phytopharmaceuticals have long been used as official medicine in different countries around the world. In Mexico, they were recently introduced. One of the most prescribed phytopharmaceuticals is derived from the Hypericum perforatum species. This plant, commonly known as St. John´s Wort, is widely used in traditional herbal medicine fo...
Article
Full-text available
The aim of the study was the identification of the most frequently used plants by patients with DM2 with access to public health services in Morelos, Mexico. A questionnaire was employed with 259 patients with DM2 who regularly utilize medicinal plants as a complementary therapy, and another 259 patients who only use the pharmaceutical prescription...

Citations

... The number of study participants in clinical trials ranged from 10 to 400 participants [11][12][13]. Two studies included patients with a preexisting condition, one included patients with type 2 diabetes mellitus and the other included patients with HIV [14,15]. ...
... Zu den Prinzipien der klientenzentrierten Gesprächspsychotherapie (Rogers, 1951) gehören bedingungsfreies Akzeptieren des "Klienten", einfühlendes Verstehen und Echtheit. Der Schwerpunkt bei der Behandlung einer Panikstörung mit Agoraphobie liegt bei folgenden Themen (Teusch u. ...
... In Mexico, Doctor Mora, Guanajuato is the locality where the first studies in a natural population botanically classified as G. glauca were carried out (Osuna et al. 1999). Subsequent studies showed that plants from this locality have anxiolytic and sedative activities in both, mice (Cardoso-Taketa et al. 2008;Sharma et al. 2012a) and humans (Herrera-Arellano et al. 2012;Romero-Cerecero et al. 2018 with anxiolytic and sedative effects (Cardoso-Taketa et al. 2008;Sharma et al. 2012a). Furthermore, anti-inflammatory effects of these metabolites have been proposed using an in vivo model in mice (González-Cortazar et al. 2014). ...
... Dolorez et al. [26] ont révélé que l'extrait hexanique des graines de Thevetia peruviana était capable de réduire la prise de poids chez les souris présentant une obésité induite par le glutamate mono sodium. En effet, l'administration orale de l'extrait hexanique de T. peruviana pendant 7 semaines était capable de diminuer le gain de poids jusqu'à 24,1% chez les souris sans observer le développement d'une résistance à l'insuline. ...
... Despite its importance, few studies have been conducted to validate only some of its extensive properties. Specifically, they have mainly focused on evaluating its antifungal properties [12][13][14][15][16][17][18][19], its action against different types ...
... Biological effects of topical herbs related to RAS. encecalin comprises a majority compound while galactin is identified as a wound healing promoting compound. This component was capable of constantly encourage cellular proliferation of normal human skin cells (HFS-30).12 ...
... The effectiveness of a standardized extract of A. pichinchensis was proven to heal chronic venous leg ulcers [18]. In another study, a cream containing an extract of A. pichinchensis was topically used by diabetic patients with foot ulcers; the results showed that this treatment decreased the healing time and lesion size, although no significant differences were observed [22]. ...
... NPDR and inflammation phase of diabetic wound healing, namely the early stages of both diseases, are prolonged, associated with persistent infiltration of neutrophils and with increased permeability of blood vessels [10, 56, 57]. Conversely, the proliferation phase of diabetic wound healing is impaired due to insufficient angiogenesis and inhibition of fibroblast proliferation [247][248][249][250], whereas exaggerated angiogenesis and fibrosis occur in PDR (Fig. 4) [38, 39]. ...
... Although the availability of drugs for the treatment and control of diabetes is varied, 80% of the world population uses also plants as medicinal remedy which, according to the World Health Organization (WHO), [1,2] is considered the first alternative treatment for several pathologies in underdeveloped countries. [3][4][5] Traditional herbal medicine may be used in addition to or as alternative pharmacological ...
... For example, in A. espinosarum, Díaz-Peralta et al. [33] recorded up to 20 compounds among the most relevant neo-clerodane diterpenes, flavonols, flavanones and flavones: taxifolin, naringenin, sakuranetin, persicogenin, apigenin, acacetin and kaempferol. In A. pichinchensis, Romero-Cerecero et al. [34] determined chlorogenic acid and glycosylated flavonoids. In A. petiolaris, Bustos-Brito et al. [11] isolated chlorogenic acid, L-chiro-inositol, benzyl 2-hydroxy-6-methoxybenzoate, benzyl 2-hydroxy-3,6-dimethoxybenzoate and 2α-tigloyloxyeperuic acid for the first time. ...