Oded Nahlieli's research while affiliated with Ben-Gurion University of the Negev and other places
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Publications (136)
Background:
The voltage-dependent anion channel 1 protein (VDAC1) plays a role in cellular metabolism and survival. It was found to be down or upregulated (overexpressed) in different malignancies but it was never studied in application to oral lesions. The purpose of this study was to retrospectively evaluate the expression of VDAC1 in biopsies o...
We aimed to collect and analyze available cases of intraoral acantholytic squamous cell carcinoma (aSCC), that consisted of the authors’ cases and cases derived from the existing literature, with an emphasis on the pathological staging and patient outcome. Our research question was whether aSCC is more aggressive than conventional SCC. The literatu...
This chapter describes the common complications associated with interventional sialoendoscopy and endoscopically assisted intraoral extraductal surgeries and presents suggestions of how to avoid and manage these complications. The complications associated with sialoendoscopy stem from different origins than those seen in radical salivary gland surg...
Orbital fractures account for up to 40% of craniofacial injuries. In this article, the authors present the transoral endoscopy-assisted plating technique for treating orbital blowout fractures (OBF). A retrospective analysis of 56 cases treated with transoral endoscopy-assisted approach was performed. Immediate versus delayed surgery decision-makin...
Sodium hypochlorite (NaOCl) is the most common irrigant used in modern endodontics due to the antimicrobial properties against bacteria, the powerful oxidative activity, and the ability to dissolve organic soft tissues. When NaOCl extrudes the apex of the root, commonly referred as "sodium hypochlorite accident," it can lead to devastating outcomes...
This study was performed to test a protocol for trans-implant treatment of chronic recurrent maxillary sinusitis (CRS), via implants with an internal removable sealing screw. The appropriate indications for treatment, optimal number of treatment sessions, and general schedule of treatment and follow-up were assessed. This was a retrospective study...
Acantholytic squamous cell carcinoma (ASCC) is an uncommon variant of squamous cell carcinoma (SCC). It is characterized by a combination of typical SCC and pseudoglandular structures, dyskeratotic cells and prominent acantholysis.
The purpose of this study was to analyze the histochemical and immunohistochemical characteristics of the intraoral va...
We aimed to immunohistochemically characterize the pattern of expression of epithelial markers in rare head and neck squamous cell carcinoma (HNSCC) variants: carcinoma cuniculatum (CC) and adenosquamous carcinoma (ASC). We also present an additional variant of HNSCC with concomitant basaloid and squamous components that has overlapping morphologic...
Background
Sonoelastography (SEG) is a non-invasive, relatively new imaging modality that maps the elastic properties through stiffness of soft tissue. Pathological conditions such as inflammation and neoplasia can change tissue elasticity; as a result, when used in the major salivary glands, this non-invasive modality may provide information that...
Objective:
The objective was to assess the outcome of graftless sinus floor augmentation associated with dental implant placement performed with an implant system that has an internal port and screw, combined with the osteotome technique.
Method and materials:
Between 2012 and 2018, 722 titanium-aluminum-vanadium implants (Ti-6Al-4V ELI, diamete...
Objective:
The present article reports how a dental implant with an internal port dental implant valve approach (DIVA) can be utilized as oroantral port to treat chronic rhinosinusitis (CRS) in a minimally invasive manner.
Method and materials:
Eleven patients (age mean 68.1 years) with CRS were subjected to the transimplant lavage technique. Fo...
In the 1990s and the beginning of the 2000s, the problem analyzed and discussed in articles on salivary gland surgery could reasonably be labeled: “minimally invasive surgery versus gland excision.”. In the 2010s, the discussion has shifted to the question of which minimally invasive method to choose. At the same time, there is no clear borderline...
With the equipment advances, the minimal invasive techniques can be applied in new surgical fields and have more applications. In this chapter, we would like to present a minimally invasive technique for treating orbital blowout fractures. The technique described has been practiced by two medical centers, The Barzilai medical center, Israel and The...
The minimally invasive (MI) implant surgery is based on two innovations: the endoscopic approach to the implantation procedure and the endoscopy-friendly smart implant. The proper changes in the construction of the dental implant may solve three problems, i.e., (1) to reduce risk of complications; (2) to improve the maxillary sinus lifting procedur...
The morbidity following traditional surgery of the salivary glands is well documented and includes postsurgical complications such as the Frey’s syndrome, complete or partial facial nerve damage, facial scarring, greater auricular nerve numbness, sialocoeles and salivary fistula. The avulsion of the salivary duct, secondary strictures, gland swelli...
Objective:
The purpose of this article is to describe long-term results of the dynamic implant valve approach (DIVA) for the dental implant procedures when the implant system with internal ports was used.
Method and materials:
During 2012 to 2015, 378 titanium-aluminum-vanadium implants (Ti6Al4V ELI; diameter 3.75 mm; length 11.5 and 13 mm) were...
Sonography has established itself as the primary imaging technique in the diagnosis of salivary gland diseases. A sonographic examination is generally sufficient to diagnose sialolithiasis. If chronic sialadenitis or sialadenosis is suspected and if sonographic findings turn out to be insufficient, a conventional sialography may be required in spec...
Objective
The current article describes our experience, combined with analysis of the emerging literature, presenting suggestions of how to avoid the complications that may arise during or follow endoscopic or endoscopy-assisted surgery of the salivary glands.
Methods
In a retrospective study, the surgical data of 498 consecutive patients that wer...
Purpose:
This study describes the use of an innovative dynamic implant valve approach (DIVA) for dental implant placement and sinus augmentation procedures.
Materials and methods:
The DIVA implant system was tested in vitro for leakage and mechanical fatigue. A closed sinus elevation procedure with a gel-type bone substitute was performed using...
Salivary gland impairment after radioiodine therapy (RIT) is a well-known iatrogenic artifact that includes recurrent episodes of sialadenitis, hyposalivation, dysgeusia, and dysphagia. Several therapy modalities have been suggested over the years to decrease these effects on the salivary glands. However, in cases where the salivary gland system is...
To conduct a systematic review with meta-analysis to determine the efficacy and safety of sialendoscopy in the treatment of obstructive diseases of the salivary glands in adults.
MEDLINE, EMBASE, and the Cochrane Library (no lower limit to October 2010). Reference lists were searched for identification of relevant studies.
Prospective or retrospect...
The aim of this study was to review the advantages, limitations, and international interdisciplinary expert perspectives and contrasts of salivary gland endoscopy and transoral techniques in the diagnosis and management of salivary gland calculi and their adaptation in North America. The transition from transcervical approaches to strictly sialendo...
A successful outcome of endodontic treatment depends to a large extent on accurate intraoperative findings. Conventionally, micromirrors and microprobes have been used for this purpose. The dental operating microscope (DOM) has been implemented to enhance visibility during dental procedures. However, the microscope, a sizable tool, remains between...
To asses the possibility of an endoscopic technique to diagnose, treat, and maintain the salivary glands in patients with Sjögren syndrome and systemic lupus erythematosus.
A total of 8 patients with Sjögren syndrome and 2 with systemic lupus erythematosus with affected salivary glands were included in the present study. The treatment approach incl...
To describe an innovative miniature visualization surgical endoscope and endoscopic techniques applicable to dental implant procedures.
A newly developed modular dental implant endoscope is introduced, and the first impressions from its use in different implant procedures are reported.
Details of the device that combines an endoscope, irrigation ca...
To assess a combined external lithotripsy-sialoendoscopy method developed for advanced salivary gland sialolithiasis.
A total of 94 patients (43 males and 51 females) underwent these treatment methods. Of these 94 patients, 60 had pathologic features in the submandibular gland and 34 in the parotid gland. A miniature external lithotripter was used,...
This article presents and discusses advanced minimally invasive sialoendoscopy and combined methods: endoscopy, endoscopic-assisted techniques, and external-lithotripsy combined procedures. It also presents rare situations and complications encountered during sialoendoscopic procedures. Sialoendoscopy is a relatively novel technique, which adds sig...
The results of endoscope-assisted parotid surgery are presented as a minimally invasive alternative to parotidectomy for large parotid stones. From 1999 to 2007, 70 patients with parotid sialoliths were treated by minimally invasive surgical techniques in three specialist centres. At surgery a combination of sialoendoscopic and ultrasound examinati...
To describe an innovative endoscopic technique for root canal treatment.
Root canal treatment was performed on 12 patients (15 teeth), using a newly developed endoscope (Sialotechnology), which combines an endoscope, irrigation, and a surgical microinstrument channel.
Endoscopic root canal treatment of all 15 teeth was successful with complete reso...
Diabetes mellitus is the most prevalent endocrine disease, comprising the third highest cause of disability and morbidity in the Western world. In the past, implant placement was contraindicated in diabetic patients because of increased risk for implant failure and infection. Publications in recent years have shown success rates for dental implants...
Obstructive sialadenitis, with or without sialolithiasis, represents the most common inflammatory disorder of the major salivary glands, and sialolithiasis is one of the major causes of sialadenitis. Calculi in the salivary glands can be found in 1.2% of the general population. Other common causes of salivary gland obstruction are ductal strictures...
A clear differential diagnosis between oral and pharyngeal dysphagia remains an unsolved problem. Disorders of the oral cavity are frequently overlooked when dysphagia/odybophagia complaints are assessed. Surface electromyographic (sEMG) studies were performed on randomly assigned patients with oral and pharyngeal pathology to evaluate their dyspha...
Juvenile recurrent parotitis (JRP) is characterized by intermittent swelling of one or both parotid glands simultaneously or on different occasions. The peak incidence of JRP is between the ages of 3 and 6 years, with predominance among males. The etiology and mechanism are still unknown. The diagnosis is made on a clinical basis and is confirmed b...
To evaluate the application of minimally invasive techniques in the management of salivary stones.
The incidence of salivary calculi is 60 cases/million/year, with most stones situated in the mid or proximal duct. The current treatment of these stones is adenectomy. This paper reports the results of minimally invasive methods of stone removal that...
Objective:
The purpose of this article is to describe innovative surgical techniques for treatment of salivary gland injuries caused by facial rejuvenation procedures.
Methods:
Between 2001 and 2007, a total of 14 patients, all females ages 46 to 70 who suffered from salivary gland injuries caused by facial rejuvenation procedures, were treated,...
Implant-based prosthetic restoration and oral rehabilitation is a very popular modality of treatment, with excellent success rates. Although a relatively safe procedure, implant insertion has its risks, which have been described in the literature. This article describes an as-yet unreported complication following implant insertion-salivary gland in...
This article describes a new endoscopic approach for orbital floor fractures, reduction, and fixation and reports the clinical results.
Ten patients who sustained either a comminuted or trap door orbital floor fracture were treated in 2 medical centers following the same surgical protocol. The indications for orbital reconstruction were limited eye...
Objective:
The purpose of this study was to describe an innovative surgical technique for the removal of posterior and hilar stones of the submandibular salivary duct.
Methods:
Between 1999 and 2005, 172 patients who had sialolithiasis of the submandibular duct were treated primarily by transoral incision and marsupialization of the duct and sal...
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Calcifications found in routine and normal radiographs of the oral and facial region may turn out to be an interesting diagnosis. Although most of the radiopacities may be sialoliths, other differential diagnoses must not be exempted, such as calcified lymph nodes, phleboliths and other vascular calcifications, tuberculosis of lymph nodes or of the...
During the last 13 years, there has been a growing interest in and use of minimally invasive treatment techniques. Salivary gland endoscopes provide an accurate means of diagnosing and providing minimally invasive surgical treatment for salivary gland diseases.
The authors review the relevant literature and provide the history of sialoendoscopy. Th...
Background. During the last. 13 years, there has been a growing interest in and use of minimally invasive treatment techniques. Salivary gland endoscopes provide an accurate means of diagnosing and providing minimally invasive surgical treatment for salvary gland diseases. Methods. The authors review the relevant literature and provide the history...
To explore the usage of salivary gland endoscope technique as a diagnostic tool as well as a novel treatment modality for sialadenitis following radioiodine therapy.
Fifteen patients suffering from sialadenitis of the major salivary glands after I131 therapy for thyroid carcinoma underwent a single procedure of sialoendoscopy under local anesthesia...
Endoscopic applications of Erbium:YAG lasers are still very limited due to lack of appropriate fiber delivery capabilities. Recent reports on potential advantages of this laser for lithotripsy of ureteral stones prompted us to develop an Er:YAG fiber delivery system for endoscopic lithotripsy of salivary stones. We report on the development of this...
The aim of this study was to document sensory changes in the supraorbital, infraorbital, and mental nerve distributions following acute and chronic maxillary and frontal sinusitis.
Seven patients with a total of 14 infected sinuses were included in the study. Neurosensory function was evaluated by measuring the electrical detection threshold for la...
Surface electromyographic (sEMG) studies were performed on 40 adult patients following extraction of lower third and second molars to research the approach and limitations of sEMG evaluation of their odynophagia complaints.
Parameters evaluated during swallowing and drinking include the timing, number of swallows per 100 cc of water, and range (amp...
To provide a description of surface electromyography (sEMG) of spontaneous saliva swallowing (SSS) and monitoring of swallow rate in patients with salivary gland diseases.
Numbers of SSS obtained during 2 hours of sEMG monitoring were compared with sialometry data for healthy volunteers (n = 100), patients with Sjögren syndrome (n = 10), and patien...
We present the case of a sailor who sustained a penetrating grease gun injury to his face, and the challenging subsequent series of events.
Juvenile recurrent parotitis (JRP) is a nonobstructive, nonsuppurative parotid inflammation in young children. Causative factors, such as local autoimmune manifestation, allergy, infection, and genetic inheritance, have been suggested, but none of them has been proved to date. Until now, treatment of JRP was divided into conservative observation an...
To study the effect of dexamethazone and dipyrone on sensory changes in the innervation territories of the inferior alveolar, infraorbital, and lingual nerves caused by third molar extractions.
Fourteen patients (8 men and 6 women) were divided randomly into 2 groups. The first group received dipyrone preoperatively, while the second group received...
Evaluating sensory nerve damage is a challenging and often frustrating process. Diagnosis and follow-up is usually based on the patient's history and gross physical evaluation in addition to simple sensory tests such as brushing or pin prick. Based on evidence accumulated from clinical and animal experiments, quantitative sensory testing (QST) has...
Nerve injury is a well-known complication following oral and maxillofacial surgery. Direct trauma, inflammation and infection are postoperative neural disturbances main causes. The most inflicted nerves associated with endosseous implant placement are those innervating the mandible: the inferior alveolar nerve, the mental nerve and the lingual nerv...
Heat and electrical detection thresholds were assessed in 72 patients suffering from painful temporomandibular disorder. Employing widely accepted criteria, 44 patients were classified as suffering from temporomandibular joint (TMJ) arthralgia (i.e. pain originating from the TMJ) and 28 from myalgia (i.e. pain originating from the muscles of mastic...
We sought to assess the efficacy of sialoendoscopic mechanical retrieval techniques for the treatment of obstructive salivary gland disease. This study documents the authors' long-term experience with mechanical retrieval techniques, the long-term results of the procedures, the technical issues, the techniques that have been used, and the advantage...
Piercing has become so popular during the last 20 to 30 years that many physicians are now treating patients with piercings and dealing with its side effects. We present 3 cases that illustrate the complications of tongue piercing (ie, infection, bleeding, and embedded ornaments). We describe the methods for inserting the ornaments to illustrate th...
This article describes the use of combined endoscopic and ultrasound approach to locate and to extract impacted parotid stones, which cannot be retrieved by intraoral approach alone.
A total of 12 parotid glands from 7 women and 5 men (age range, 35 to 62 years) with parotid sialoliths were treated with the combined method. Eleven of 12 of the proc...
On the basis of this preliminary report series of patients, it seems that the achievement of fixed anchorage for nail prostheses is feasible using the process of osseointegration, the use of standard dental implants, and abutment and maxillofacial rehabilitation laboratory to build the superstructure system. The osseointegrated procedure is relativ...
The most frequent cause of defect in the mandible is tumor-related surgery. Larger defects or anterior arch defects cause severe morbidity due to disturbances in function and esthetics.
To assess the outcome of free tissue transfer for mandible reconstruction.
Since 1998 we operated on 11 patients with mandible defects using the fibula flap as the...
Injury to the oropharynx can be potentially life threatening. Innocent-looking injuries of the oropharynx may result in intravascular thrombosis of the internal carotid artery. The symptoms often appear some time after the initial injury. We present a case in which an apparently minor injury of the oropharynx developed into a life-threatening throm...
The purpose of this study was to assess the sensory function of trigeminal nerve A-beta fibers in suspected soft tissue oral malignancies.
Twenty-three patients referred for the evaluation of an oral lesion suspected of malignancy were included in the study. All lesions were classified as in, near, or out of the nerve territory containing the lesio...
An abstract is unavailable. This article is available as HTML full text and PDF.
The purpose of this study was to reintroduce a rather simple, safe, minimally invasive, and rapid alternative procedure for the treatment of recurrent dislocation of the condyles.
Subjects were 3 patients (5 joints) who suffered from recurrent condyle dislocation. The technique consisted of visually identifying a line from tragus to the eye angle....
This article describes the use of sialoendoscopy for diagnosis and treatment of strictures and kinks in the major salivary glands ducts.
Thirty-four salivary glands with obstruction were diagnosed as having ductal kinks or strictures. Strictures were diagnosed by sialography and sialoendoscopy, kinks were diagnosed mainly by sialography, whereas en...
Skin preparation burns associated with chemical agents are uncommon. They occur most frequently in patients placed in the lithotomic position undergoing gynaecologic or urologic operations, the burn being on the buttocks, and in those undergoing orthopaedic operations, the burn being on the extremities and under a tourniquet. The basic mechanism in...
Superficial or total parotidectomy is always a challenge to the surgeon because of the great amount of attention that is directed toward identifying the facial nerve. The success of the surgery depends on complete resection of the tumor while also preserving the facial nerve. Currently, the accepted technique for identifying the main trunk of the f...
Leiomyosarcoma is a malignant tumor that can arise from smooth muscle or from pluripotential, undifferentiated mesenchymal cells. In the head and neck, smooth muscle is sparse and found mainly in the walls of blood vessels and the erector pili muscles of the skin. The occurrence of leiomyosarcoma in the head and neck region is rare. The purpose of...
Pediatric sialolithiasis is a rare condition. This article characterizes 15 cases in children between 5 and 14 years of age. The diagnoses of this condition were made with routine radiograph and ultrasound, as well as with sialography whenever possible. Sialoendoscopy was performed as a diagnostic and treatment modality. Thirteen of the 15 affected...
The following report describes an unusual iatrogenic contact burn from a heated dental instrument. The potential hazard of inflicting a contact burn using a glass bead sterilizer must be kept in mind.
The endoscopic procedure for placement and activation of a distraction device for mandibular advancement has been previously reported. The purpose of this study was to demonstrate the feasibility of endoscopic exposure, dissection and osteotomy for mandibular set-back. Two cadaver and three anesthetized minipigs were used in this study. Access to t...
To assess the efficacy of the sialoendoscopic technique for treatment of inflammatory salivary gland diseases. This report documents the authors' long-term experience with sialoendoscopy and discusses the long-term results of the procedure, technical issues, and varieties that they have utilized, as well as the advantages and limitations of this mo...
Three cases of accessory parotid gland lesions are reported. The literature concerning accessory gland disease and its diagnosis and treatment is reviewed.
Videoendoscopy is a minimally invasive procedure for the diagnosis and therapy of sialopathies of the major salivary glands. The main indication is sialolithiasis of the submandibular and parotid glands. Sialoendoscopy offers, on the one hand, a diagnostic method for radiolucent calculi in particular and, on the other, can be used to simultaneously...
Purpose:
This article describes the use of endoscopy for diagnostic and surgical intervention in the major salivary glands of patients who have obstructive pathology, reviews past experience with this technique, and describes the microanatomy and pathophysiologic findings encountered during endoscopy of these glands.
Patients and methods:
A tota...
Citations
... Fang ve ark. (2022) Çin'de yaptığı çalışmaya 180 kritik yenidoğanı dahil etmiştir. STABLE ile hemşireler tarafından hastane içi nakli gerçekleşen yenidoğanlar (n=92) girişim grubu olarak belirlenmiştir. ...
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... При неефективності консервативного підходу до лікування на протязі 2 тижнів доцільним є проведення МРТ (КТ)-діагностики та хірургічного втручання з видаленням некротизованих тканин [4]. ...
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... Salivary gland diseases, in which sialolithiasis is one of the major causes of sialadenitis, are increasingly common and account for approximately 50% of major salivary gland diseases. 15,16 Traditional diagnostic methods for sialolithiasis can be applied to visualize the stone directly or indirectly through ductal dilatation before the site of obstruction. 17 However, they would not be ideal for detecting small, noncalcified intraductal stones and unable to distinguish salivary stones from other types of calcifications around the submandibular glands, such as calcified lymph nodes or phleboliths. ...
... In a review, Neronov et al. mentioned 25 cases of IMT, 18 were in the mandible, and 7 were in the maxilla. 16 Although IMTs have rarely been described as primary in the jaws, the epithelioid variant has not been reported. A case of IMT in the maxilla with sarcomatous changes has been reported, but the tumor cells' epithelioid morphology was not described. ...